[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100577815":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":30,"centralContacts":34,"locations":40,"responsibleParty":58,"collaborators":25,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":25,"eligibilityCriteria":67,"healthyVolunteers":63,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":25,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":25,"overallStatus":43,"whyStopped":25,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"Kaohsiung Veterans General Hospital.","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"combined FSH and LH","EXPERIMENTAL","Participants receive combined FSH and LH during controlled ovarian stimulation in IVF cycle",[13],"Drug: FSH and LH",{"label":15,"type":16,"description":11,"interventionNames":17},"FSH alone","ACTIVE_COMPARATOR",[18],"Drug: FSH",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","FSH and LH","In the study group, participants receive FSH and LH in IVF cycle",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"FSH","In the control group, participants receive FSH alone in IVF cycle",[15],[31],{"name":32,"affiliation":5,"role":33},"Kuan-Hao Tsui","STUDY_CHAIR",[35],{"name":36,"role":37,"phone":38,"phoneExt":25,"email":39},"Li-Te Lin","CONTACT","+88673464027","litelin1982@gmail.com",[41],{"facility":42,"status":43,"city":44,"state":25,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Kaohsiung Veterans General Hospital","RECRUITING","Kaohsiung City","81362","Taiwan","TW",{"type":49,"coordinates":50},"Point",[51,52],120.31333,22.61626,{"lat":52,"lon":51},[55,56],{"name":36,"role":37,"phone":38,"phoneExt":25,"email":39},{"name":32,"role":37,"phone":57,"phoneExt":25,"email":25},"+886-7-3422121",{"type":59,"investigatorFullName":36,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Attending doctor, Department of Obstetrics and Gynecology","100577815","effects-of-lh-and-fsh-on-metabolic-regulation-in-cumulus-cells-100577815",false,"NCT06803199","Effects of LH and FSH on Metabolic Regulation in Cumulus Cells","Investigation of the Combined Effects of Luteinizing Hormone and Follicle-Stimulating Hormone on Metabolic Regulation in Cumulus Cells","Inclusion Criteria:\n\n* Age 35-40 years\n* BMI 18-30 kg\u002Fm2\n* planning to undergo IVF cycles\n\nExclusion Criteria:\n\n* Primary ovarian insufficiency\n* history of oophorectomy\n* receiving oocyte donation\n* Chromosome anomaly\n* Congenital uterine anomaly\n* Severe intrauterine adhesion\n* Malignancy\n* Using hormone therapy or supplements in recent 3 months","FEMALE","35 Years","40 Years",{"count":72,"type":73},60,"ESTIMATED","INTERVENTIONAL",[76],"NA","The combined use of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) has improved IVF pregnancy rates in infertile women aged 35-40, but its mechanisms remain unclear. This prospective study will examine how FSH and LH combined treatment affects cumulus cell energy metabolism. Sixty participants will be divided into two groups receiving either combined therapy or FSH alone. The study will analyze patient characteristics, infertility history, and compare mitochondrial function in cumulus cells to evaluate treatment effectiveness.",[79],"Unrecognized Condition","2025-01-27",{"date":82,"type":83},"2025-01-31","ACTUAL",{"date":85,"type":83},"2024-12-01",{"date":87,"type":73},"2027-12-31",{"name":5,"class":6},1]