[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100457791":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":34,"locations":42,"responsibleParty":59,"collaborators":25,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":66,"acronym":25,"eligibilityCriteria":67,"healthyVolunteers":64,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":25,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":82,"overallStatus":44,"whyStopped":25,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"University of Gran Rosario","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Low load training with blood flow restriction (LL-BFR) group.","EXPERIMENTAL","All participants in this arm will use a BFR tourniquet system during the execution of two exercises, unilateral dynamic standing and sitting calf-raises, with a training load of 20% 1 repetition maximum (RM), being progressively increased by 5% every four weeks. Dynamic strength testing will be implemented to re-evaluate the current strength level and adequately adjust the load, using the PowerLift app, which was validated by Balsalobre-Fernandez in 2017. For each exercise, each participant will perform four sets with 30 repetitions the first set and 15 repetitions in the subsequent three sets, counting a total of 75 repetitions. All exercises will be performed in full range of motion (full plantar flexion to full dorsal flexion), with an interset rest period of 1 minute. Three minutes rest was provided between exercises.",[13],"Other: Low Load Training with Blood Flow Restriction",{"label":15,"type":16,"description":17,"interventionNames":18},"High load training (HLT) group.","ACTIVE_COMPARATOR","The HLT group will performed the same exercises than the BFR group, however with a training load of 70% 1RM, being progressively increased by 5% every four weeks from 70% to 80%. This protocol will consist of three sets of 6-12 repetitions. Dynamic strength testing will be implemented to re-evaluate the current strength level and adequately adjust the load, using the PowerLift app, which was validated by Balsalobre-Fernandez in 2017. All exercises will be performed in full range of motion, with an interset rest period of 1 minute and a rest period between exercises of 3 minutes.",[19],"Other: High Load Training",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Low Load Training with Blood Flow Restriction","A 12-cm-wide pneumatic nylon tourniquet will be proximally positioned with a snug fit on each thigh. Previously, arterial occlusion pressure (AOP) will be determined using a handheld Doppler Ultrasound in a standing position for each participant. For training routines, cuff pressure will be set to 50% of each individual´s AOP and will be keep inflated during the entire session including the interset rest period of 1 minute. Between the two exercises, the cuff will be deflated for 3 minutes.",[9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"High Load Training","All participants in this arm will do two exercises, unilateral dynamic standing and sitting calf-raises, with a training load of 70% 1RM, being progressively increased by 5% every four weeks from 70% to 80%. This protocol will consist of three sets of 6-12 repetitions with a interset rest period of 1 minute and 3 minutes rest between exercises.",[15],[31],{"name":32,"affiliation":5,"role":33},"Gonzalo Elias, PT","PRINCIPAL_INVESTIGATOR",[35,39],{"name":32,"role":36,"phone":37,"phoneExt":25,"email":38},"CONTACT","543416051190","gelias@ugr.edu.ar",{"name":40,"role":36,"phone":41,"phoneExt":25,"email":25},"Leonardo Intelangelo, MSc, PT","543416758135",[43],{"facility":5,"status":44,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"RECRUITING","Rosario","Santa Fe Province","2000","Argentina","AR",{"type":51,"coordinates":52},"Point",[53,54],-60.63932,-32.94682,{"lat":54,"lon":53},[57,58],{"name":32,"role":36,"phone":37,"phoneExt":25,"email":38},{"name":40,"role":36,"phone":41,"phoneExt":25,"email":25},{"type":33,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Gonzalo Elias","Physiotherapist","100457791","effects-of-low-load-resistance-training-with-blood-flow-restriction-in-patients-with-achilles-tendinopathy-100457791",false,"NCT05241197","Effects of Low-load Resistance Training With Blood Flow Restriction in Patients With Achilles Tendinopathy","Inclusion Criteria:\n\n* Clinical diagnosis of unilateral MAT.\n* Achilles pain \\> 3 months.\n* Age ranging between 18 to 50 years, both genders.\n* Read and speak Spanish well enough to provide informed consent and follow study instructions.\n* Can attend in-clinic treatments 2-3 x weekly for the next 12 weeks.\n\nExclusion Criteria:\n\n* Any ankle or foot surgery.\n* History of Achilles rupture.\n* Heel pain in the last 3 months.\n* Systemic disorders\u002Fdiseases.\n* History of deep venous thrombosis, hypertension or blood clotting disorder.\n* Body mass index \\> 30kg\u002Fm2.\n* Self-report of pregnancy.\n* Drug use (local steroid injection or systemic fluoroquinolones).\n* Pain \\\u003C 2\u002F10 of average pain on NPRS.\n* VISA A score \\> 90%.\n* Unable to perform any of the exercises of the study.","ALL","18 Years","50 Years",{"count":72,"type":73},52,"ESTIMATED","INTERVENTIONAL",[76],"NA","Midportion Achilles tendinopathy (MAT) is a common overuse injury of the lower extremity characterized by the presence of pain, restricted function and interruption of sport activities. Conservative management of MAT has been suggested as the first line of treatment. Actually, there are several exercise programs with beneficial effects on pain and function among which high load training stands out. However, this training modality is inherently difficult to implement in certain populations and pathological conditions due to their inability to tolerate this mechanical stress. In this sense, low load training with blood flow restriction (BFR-LLT) emerges as an effective option in producing hypertrophic adaptations with low intensities (30% 1RM). However, this training modality has not yet been studied in tendon pathology. The aim of this study is to evaluate the potential clinical effects of BFR-LLT in comparison with HLT in patients with chronic MAT.",[79,80,81],"Achilles Tendinopathy","Achilles Tendon Pain","Tendon Injuries",[83,84],"Blood Flow Restriction","Rehabilitation","2024-12-03",{"date":87,"type":88},"2024-12-06","ACTUAL",{"date":90,"type":88},"2022-04-29",{"date":92,"type":73},"2026-08",{"name":5,"class":6},1]