[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100607243":3},{"organization":4,"armGroups":7,"interventions":29,"overallOfficials":33,"centralContacts":41,"locations":53,"responsibleParty":76,"collaborators":33,"id":80,"slug":81,"hasResults":82,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":86,"eligibilityCriteria":87,"healthyVolunteers":88,"sex":89,"minAge":90,"maxAge":33,"enrollmentInfo":91,"targetDuration":33,"studyType":94,"phases":95,"briefSummary":97,"conditions":98,"keywords":33,"overallStatus":56,"whyStopped":33,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":112},{"fullName":5,"class":6},"National Health Research Institutes, Taiwan","OTHER",[8,14,19,24],{"label":9,"type":10,"description":11,"interventionNames":12},"MBSR","ACTIVE_COMPARATOR","Mindfulness-Based Stress Reduction",[13],"Behavioral: MBSR",{"label":15,"type":10,"description":16,"interventionNames":17},"MBWC","Mindfulness-Based Well-Being Curriculum",[18],"Behavioral: MBWC",{"label":20,"type":10,"description":21,"interventionNames":22},"MBCI","Mindfulness-Based Curriculum for Insomnia",[23],"Behavioral: MBCI",{"label":25,"type":6,"description":26,"interventionNames":27},"BSI","Brain Stimulation Intervention",[28],"Device: BSI",[30,34,36,38],{"type":31,"name":9,"description":11,"armGroupLabels":32,"otherNames":33},"BEHAVIORAL",[9],null,{"type":31,"name":15,"description":16,"armGroupLabels":35,"otherNames":33},[15],{"type":31,"name":20,"description":21,"armGroupLabels":37,"otherNames":33},[20],{"type":39,"name":25,"description":26,"armGroupLabels":40,"otherNames":33},"DEVICE",[25],[42,48],{"name":43,"role":44,"phone":45,"phoneExt":46,"email":47},"Ai-Ling Hsu, PhD.","CONTACT","+886-5-6327369","143","alhsu@nhri.edu.tw",{"name":49,"role":44,"phone":50,"phoneExt":51,"email":52},"Changwei W. Wu, PhD.","+886-2-66202589","10518","sleepbrain@tmu.edu.tw",[54,69],{"facility":55,"status":56,"city":57,"state":33,"zip":58,"country":59,"countryCode":60,"cosmosGeoPoint":61,"geoPoint":66,"contacts":67},"Shuang Ho Biomedical Park, Taipei Medical University","RECRUITING","New Taipei City","235603","Taiwan","TW",{"type":62,"coordinates":63},"Point",[64,65],121.45703,25.06199,{"lat":65,"lon":64},[68],{"name":49,"role":44,"phone":50,"phoneExt":51,"email":52},{"facility":70,"status":71,"city":72,"state":33,"zip":73,"country":59,"countryCode":60,"cosmosGeoPoint":33,"geoPoint":33,"contacts":74},"National Center for Geriatrics and Welfare Research","NOT_YET_RECRUITING","Yunlin","632007",[75],{"name":43,"role":44,"phone":45,"phoneExt":46,"email":47},{"type":77,"investigatorFullName":78,"investigatorTitle":79,"investigatorAffiliation":5,"oldNameTitle":33,"oldOrganization":33},"PRINCIPAL_INVESTIGATOR","Ai-Ling Hsu","Assistant Investigator","100607243","effects-of-mindfulness-or-brain-stimulation-intervention-for-late-life-adults-in-taiwan-urban-and-rural-areas-100607243",false,"NCT07186023","Effects of Mindfulness or Brain Stimulation Intervention for Late-life Adults in Taiwan Urban and Rural Areas","Intervention Evaluation for Late-life Depression in Taiwan Urban and Rural Areas: Long-term Tracking and Prediction of Non-pharmaceutical Interventions by Smart AI Technologies","PredictNPI","Inclusion Criteria for individuals participating in mindfulness-based Interventions:\n\n* Literate or have received an education above the elementary level.\n* Have normal or corrected vision and hearing, able to communicate and understand explanations.\n* Right-handed individuals as assessed by the Edinburgh Handedness Inventory.\n\nExclusion Criteria for individuals participating in mindfulness-based Interventions:\n\n* Individuals with dementia, stroke, cerebrovascular disease, brain injury, epilepsy, or Parkinson's disease.\n* Individuals with neurological system disorders.\n* Individuals with alcohol or drug dependence.\n* Individuals with other major physical illnesses, such as diabetes, heart failure, or endocrine abnormalities, or those who have experienced an acute myocardial infarction within the past three months.\n* Individuals with metal objects in the body that cannot undergo magnetic resonance imaging (MRI), such as cardiac pacemakers, vascular clips, hearing aids, artificial joints, steel pins, etc.\n* Individuals with Claustrophobia.\n* Individuals in pregnancy or possibility of pregnancy.\n\nInclusion Criteria for individuals participating in brain stimulation Intervention:\n\n* Individuals diagnosed with major depressive disorder by psychiatrists according to the Diagnostic and Statistical Manual, and who can cooperate with the psychiatric outpatient clinic regulations.\n* Literate or have received an education above the elementary level.\n* Have normal or corrected vision and hearing, able to communicate and understand explanations.\n* Right-handed individuals as assessed by the Edinburgh Handedness Inventory.\n* Individuals are prescribed brain stimulation therapy by clinical physicians.\n\nExclusion Criteria for individuals participating in brain stimulation Intervention:\n\n* Individuals with dementia, stroke, cerebrovascular disease, brain injury, epilepsy, or Parkinson's disease.\n* Individuals with neurological system disorders.\n* Individuals with alcohol or drug dependence.\n* Individuals with other major physical illnesses, such as diabetes, heart failure, or endocrine abnormalities, or those who have experienced an acute myocardial infarction within the past three months.\n* Individuals with metal objects in the body that cannot undergo magnetic resonance imaging (MRI), such as cardiac pacemakers, vascular clips, hearing aids, artificial joints, steel pins, etc.\n* Individuals with Claustrophobia.\n* Individuals in pregnancy or possibility of pregnancy.",true,"ALL","55 Years",{"count":92,"type":93},124,"ESTIMATED","INTERVENTIONAL",[96],"NA","This randomized controlled trial will examine the effects of mindfulness-based interventions and brain stimulation interventions on cognitive function and psychological well-being in older adults. The study will employ a comprehensive assessment approach incorporating psychological evaluations, behavioral assessments, psychophysiological measurements, and neuroimaging analyses to characterize the outcome of nonpharmaceutical interventions in improving geriatric well-being or reducing depression severity.",[99,100,101,102,26],"Late-Life Adults","Late-Life Prodromal Depression","Late-Life Depression","Mindfulness","2025-09-15",{"date":105,"type":106},"2025-09-22","ACTUAL",{"date":108,"type":106},"2025-08-01",{"date":110,"type":93},"2028-12",{"name":5,"class":6},2]