[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100634240":3},{"organization":4,"armGroups":7,"interventions":16,"overallOfficials":31,"centralContacts":35,"locations":22,"responsibleParty":43,"collaborators":22,"id":46,"slug":47,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":22,"eligibilityCriteria":52,"healthyVolunteers":48,"sex":53,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":22,"studyType":59,"phases":60,"briefSummary":62,"conditions":63,"keywords":65,"overallStatus":69,"whyStopped":22,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":22},{"fullName":5,"class":6},"Boston University Charles River Campus","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Rhythmic auditory stimulation during walking","EXPERIMENTAL","All participants will be exposed to different walking conditions including music, metronome, and no music or metronome",[13,14,15],"Behavioral: Rhythmic Auditory Stimulation with music","Behavioral: Rhythmic Auditory Stimulation with metronome","Behavioral: Control",[17,23,27],{"type":18,"name":19,"description":20,"armGroupLabels":21,"otherNames":22},"BEHAVIORAL","Rhythmic Auditory Stimulation with music","Walking to rhythmic Auditory Stimulation with music",[9],null,{"type":18,"name":24,"description":25,"armGroupLabels":26,"otherNames":22},"Rhythmic Auditory Stimulation with metronome","walking to rhythmic Auditory Stimulation with metronome",[9],{"type":18,"name":28,"description":29,"armGroupLabels":30,"otherNames":22},"Control","Walking to no music or metronome",[9],[32],{"name":33,"affiliation":5,"role":34},"Deepak Kumar, PT, PhD","PRINCIPAL_INVESTIGATOR",[36,40],{"name":33,"role":37,"phone":38,"phoneExt":22,"email":39},"CONTACT","617-358-3037","kumard@bu.edu",{"name":41,"role":37,"phone":22,"phoneExt":22,"email":42},"Yiwen Yang, DPT","ywyang@bu.edu",{"type":34,"investigatorFullName":44,"investigatorTitle":45,"investigatorAffiliation":5,"oldNameTitle":22,"oldOrganization":22},"Deepak Kumar","Associate Professor","100634240","effects-of-music-during-walking-on-pain-and-muscle-activation-in-people-with-chronic-pain-due-to-knee-osteoarthritis-100634240",false,"NCT07537114","Effects of Music During Walking on Pain and Muscle Activation in People With Chronic Pain Due to Knee Osteoarthritis","Effects of Music-Based Rhythmic Auditory Stimulation During Walking on Nociceptive Signaling and Muscle Activation in People With Chronic Pain Due to Knee Osteoarthritis","Inclusion Criteria:\n\n* Have activity related pain\n* Experience morning knee stiffness ≤ 30 minutes\n* Knee pain on most days for 3 months or more\n* Able to walk at least 20 minutes with assistance\n* Average overall knee pain severity of ≥= 4 on a 11-point numeric rating scale during previous week\n* BMI ≤ 40\n* Able to communicate using English at a level to understand the study procedures and informed consent\n\nExclusion Criteria:\n\n* Contraindications to exercise\n* Joint replacement in either hip, knee, or ankle\n* History of other disease that may involve the index joint including inflammatory joint disease such as rheumatoid arthritis, seronegative spondyloarthropathy (eg, ankylosing spondylitis, psoriatic arthritis, inflammatory bowel disease related arthropathy), crystalline disease (eg, gout or pseudogout), lupus erythematosus, knee joint infections, Paget's disease affecting the knee, or knee joint tumors.\n* Previous knee osteotomy in either knee\n* Other health conditions that impact motor functioning or prevent participation (e.g., stroke, Parkinson's disease, Alzheimer's disease, Multiple Sclerosis, diabetic neuropathy, etc.)\n* Corticosteroid or hyaluronic acid injections in either knee in the previous 3 months\n* Pregnancy (self-report)\n* Suspected or known drugs or alcohol abuse\n* Mini-mental State Examination (MMSE) score \\\u003C 24\n* Hearing impairments\n* Pain in lower back or legs that is greater than knee pain","ALL","50 Years","85 Years",{"count":57,"type":58},20,"ESTIMATED","INTERVENTIONAL",[61],"NA","The purpose of this research study is to compare muscle activation, changes in pain sensitivity, and brain function, between different walking conditions, including walking to music, walking to metronome, and walking without music or metronome.",[64],"Knee Osteoarthritis",[66,67,68],"music","rhythmic auditory stimulation","knee pain","NOT_YET_RECRUITING","2026-04-17",{"date":72,"type":73},"2026-04-22","ACTUAL",{"date":75,"type":58},"2026-08",{"date":77,"type":58},"2027-07",{"name":5,"class":6}]