[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100560048":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":7,"centralContacts":7,"locations":13,"responsibleParty":27,"collaborators":7,"id":31,"slug":32,"hasResults":33,"nctId":34,"briefTitle":35,"officialTitle":36,"acronym":7,"eligibilityCriteria":37,"healthyVolunteers":33,"sex":38,"minAge":39,"maxAge":7,"enrollmentInfo":40,"targetDuration":7,"studyType":43,"phases":7,"briefSummary":44,"conditions":45,"keywords":7,"overallStatus":48,"whyStopped":7,"lastUpdateSubmitDate":49,"lastUpdatePostDateStruct":50,"startDateStruct":53,"completionDateStruct":55,"leadSponsor":57,"locationsCount":58},{"fullName":5,"class":6},"Karlsburg Hospital","OTHER",null,[9],{"type":10,"name":11,"description":12,"armGroupLabels":7,"otherNames":7},"DEVICE","Negative Pressure Ventilation","Substitution of positive pressure ventilation by negative pressure ventilation",[14],{"facility":15,"status":7,"city":16,"state":17,"zip":18,"country":19,"countryCode":20,"cosmosGeoPoint":21,"geoPoint":26,"contacts":7},"Klinikum Karlsburg, Klinik für Anästhesiologie","Karlsburg","Mecklenburg-Vorpommern","17495","Germany","DE",{"type":22,"coordinates":23},"Point",[24,25],13.61007,53.97172,{"lat":25,"lon":24},{"type":28,"investigatorFullName":29,"investigatorTitle":30,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","Prof. Dr. Matthias Heringlake","Principal Investigator","100560048","effects-of-negative-pressure-ventilation-on-right-ventricular-function-in-cardiological-patients-100560048",false,"NCT06572072","Effects of Negative Pressure Ventilation on Right Ventricular Function in Cardiological Patients","Effects of Negative Pressure Ventilation on Right Ventricular Function in Cardiological Patients With Reduced Right Ventricular Function.","Inclusion Criteria:\n\n* patients planned for tricuspidal clipping\n\nExclusion Criteria:\n\n* ventilatory of hemodynamic instability\n* fitting of cuirass not possible\n* unavailability of examiner","ALL","18 Years",{"count":41,"type":42},30,"ESTIMATED","OBSERVATIONAL","Patients receives induction of general anesthesia for interventional tricuspidal clipping and standard monitoring for this procedure including arterial and central venous line and transesophageal ultrasound. A cuirass for extrathoracal negative pressure ventilation is placed onto the chest but not switched on. During usual positive pressure ventilation a ventilatory, a hemodynamic and a 3D full volume ultrasounddataset of the right and left ventricle is recorded and severity of tricuspidal regurgitation examined. Afterwards negative pressure ventilation is started and positive pressure ventilation reduced as far as possible without reduction of tidal volumes. The same dataset of ventilation, hemodynamics and ultrasound is collected again during negative pressure ventilation. Afterwards the cuirass gets removed, study finished and everything proceeds as during standard procedure.",[11,46,47],"Right Ventricular Dysfunction","Right Ventricular Failure","NOT_YET_RECRUITING","2024-08-23",{"date":51,"type":52},"2024-08-26","ACTUAL",{"date":54,"type":42},"2024-09-01",{"date":56,"type":42},"2025-09-01",{"name":5,"class":6},1]