[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100595603":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":11,"centralContacts":25,"locations":31,"responsibleParty":49,"collaborators":53,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":60,"acronym":61,"eligibilityCriteria":62,"healthyVolunteers":58,"sex":63,"minAge":64,"maxAge":11,"enrollmentInfo":65,"targetDuration":11,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":11,"overallStatus":34,"whyStopped":11,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Karlsburg Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"All participants negative pressure ventilation and positive pressure ventilation","EXPERIMENTAL",null,[13,14],"Device: Negative pressure ventilation","Device: positive pressure ventilation",[16,21],{"type":17,"name":18,"description":19,"armGroupLabels":20,"otherNames":11},"DEVICE","Negative pressure ventilation","All participants are ventilated with negative pressure ventilation first",[9],{"type":17,"name":22,"description":23,"armGroupLabels":24,"otherNames":11},"positive pressure ventilation","All participants are ventilated using positive pressure ventilation after negative pressure ventilation",[9],[26],{"name":27,"role":28,"phone":29,"phoneExt":11,"email":30},"Matthias Heringlake, Prof. Dr. med.","CONTACT","038355 70-2500","Heringlake@drguth.de",[32],{"facility":33,"status":34,"city":35,"state":11,"zip":11,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Klinikum Karlsburg","RECRUITING","Karlsburg","Germany","DE",{"type":39,"coordinates":40},"Point",[41,42],13.61007,53.97172,{"lat":42,"lon":41},[45],{"name":46,"role":28,"phone":47,"phoneExt":11,"email":48},"Matthias Heringlake, Prof. Dr. Med.","004938355702500","aneathesie.karlsburg@drguth.de",{"type":50,"investigatorFullName":51,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Prof. Dr. Matthias Heringlake","Head of department for anesthesiology and critical care",[54],{"name":55,"class":6},"University Hospital Freiburg","100595603","effects-of-negative-pressure-ventilation-onto-hemodynamics-and-right-ventricular-funktion-in-patients-after-implantation-of-a-left-ventricular-assist-device-100595603",false,"NCT07034599","Effects of Negative Pressure Ventilation Onto Hemodynamics and Right Ventricular Funktion in Patients After Implantation of a Left Ventricular Assist Device.","NPV LVAD","Inclusion Criteria:\n\n* All patients after implantation of a durable left ventricular assist device\n\nExclusion Criteria:\n\n* Complication during surgery like bleeding, emergency, inability to fit the cuirass, unavailability of an investigator, unstable condition regarding circulation or ventilation","ALL","18 Years",{"count":66,"type":67},30,"ESTIMATED","INTERVENTIONAL",[70],"NA","All patients undergoing an implantation of a durable left ventricular assist device and monitored by pulmonary artery catheter showing no adverse events after surgery are included in the study and ventilated for 15 minutes using extra thoracic negative pressure ventilation and usual intrathoracic positive pressure ventilation. Hemodynamics changes between both ventilation modes, especially focussing on right ventricular function and measured by a pulmonary artery catheter, are compared.",[73,74,75],"Critical Illness","Heart Failure","LVAD","2026-02-13",{"date":78,"type":79},"2026-02-18","ACTUAL",{"date":81,"type":79},"2025-10-01",{"date":83,"type":67},"2026-12-01",{"name":5,"class":6},1]