[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100628313":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":29,"locations":35,"responsibleParty":47,"collaborators":25,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":55,"acronym":25,"eligibilityCriteria":56,"healthyVolunteers":53,"sex":57,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":25,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":69,"overallStatus":76,"whyStopped":25,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"Lahore University of Biological and Applied Sciences","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Pain neuroscience education + core stabilization","EXPERIMENTAL","Participants receive core stabilization exercises combined with structured pain neuroscience education three times per week for four weeks",[13],"Other: Pain neuroscience education + core stabilization",{"label":15,"type":16,"description":17,"interventionNames":18},"Core stabilisation exercises only","ACTIVE_COMPARATOR","Participants receive core stabilization exercises alone three times per week for four weeks without pain neuroscience education.",[19],"Other: Core stabilization exercises",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Core stabilization exercises","The control group participated in an exercise program which was founded on the principle of FITT. The participants attended 3 sessions a week in a span of four weeks. The sessions were 45 minutes long and occurred at an intermediate intensity, 10 reps per set. In the case of the intervention group, the hot pack application was applied to the area of pain followed by 10 minutes of trans-cutaneous electrical nerve stimulation (TENS) and maitland's grade I and II postero-anterior glide to manage pain. Subsequently, a structured core stabilization exercise program (bridging, bird- dog position, single knee-to-chest, curl-up, and side bridge exercises) was performed by participants",[15],null,{"type":6,"name":9,"description":27,"armGroupLabels":28,"otherNames":25},"The intervention group met thrice a week in the course of four weeks as the FITT principle dictates. All sessions took 45 minutes and were moderate in their intensity with 10 repetitions per set. The initial treatment was a 10 minutes hot pack application and a 10 minutes trans-cutaneous electrical nerve stimulation (TENS). In addition to these modalities, participants engaged in an organized program of core stabilization exercises and maitland's grade I and II postero-anterior glide to manage pain. CSE included bridging, bird-dog position, single knee-to-chest, curl-ups, and side bridges. Parallel to the exercise component, a structured module of Pain Neuroscience Education (PNE) based on the biopsychosocial model was delivered weekly, focusing on the social, psychological, and physical dimensions of pain and functional recovery.",[9],[30],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},"Maham Khalid","CONTACT","03334164339","mahamkhalid651@gmail.com",[36],{"facility":37,"status":25,"city":38,"state":25,"zip":25,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":25},"Ghurki trust and teaching hospital","Lahore","Pakistan","PK",{"type":42,"coordinates":43},"Point",[44,45],74.35071,31.558,{"lat":45,"lon":44},{"type":48,"investigatorFullName":49,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Dr. Hufsa Tariq","Assistant professor","100628313","effects-of-pain-neuroscience-education-on-pain-kinesiophobia-in-patients-with-non-specific-low-back-pain-100628313",false,"NCT07460011","Effects of Pain Neuroscience Education on Pain, Kinesiophobia in Patients With Non Specific Low Back Pain","Inclusion Criteria:\n\n\\-\n\nParticipants included in this study were male and female patients aged between 20 and 55 years diagnosed with chronic non-specific low back pain of mechanical origin lasting three months or more.\n\nIndividuals experiencing pain localized between the costal margin and gluteal folds without radiating symptoms or specific pathological causes were considered eligible.\n\nParticipants with low back pain that has persisted for more than three months reported pain intensity of greater than three months.\n\nThe study will involve those who have mechanical low back pain, which is defined as pain that is impacted by posture, movement, and physical activity but does not have a specific cause\n\nExclusion Criteria:\n\n* Participants with a history of spinal fractures, previous spine injury, malignant tumors, spondylolisthesis, or spondylolysis were excluded from this study.\n\nThe conditions associated with structural instability, neurological involvement, or serious underlying pathology.\n\nIndividuals with a history of malignant tumors involving the spine were excluded because cancer-related pain.\n\nPregnant women were also excluded from the study due to physiological, hormonal, and bio-mechanical changes that occur during pregnancy, which may alter spinal loading, pain perception, and movement patterns","ALL","20 Years","55 Years",{"count":61,"type":62},62,"ESTIMATED","INTERVENTIONAL",[65],"NA","Chronic non-specific low back pain (NSLBP) is a highly prevalent musculoskeletal condition and a leading cause of disability worldwide. Psychological factors such as fear-avoidance beliefs and kinesiophobia significantly contribute to pain chronicity, reduced physical activity, and functional limitations. Pain Neuroscience Education (PNE) is a biopsychosocial educational approach designed to reconceptualize pain as a protective output of the nervous system rather than solely a marker of tissue damage.\n\nThis randomized controlled trial aims to determine the effect of Pain Neuroscience Education combined with Core Stabilization Exercises on pain intensity and kinesiophobia in patients with chronic non-specific low back pain. A total of 62 participants aged 20-55 years with mechanical low back pain lasting ≥3 months will be randomly allocated into two groups: (1) Core Stabilization Exercises plus PNE (experimental group) and (2) Core Stabilization Exercises alone (control group). The intervention duration will be four weeks, with three sessions per week.\n\nPrimary outcomes include pain intensity measured by the Numeric Pain Rating Scale (NPRS) and kinesiophobia measured using the Fear-Avoidance Beliefs Questionnaire (FABQ). Assessments will be conducted at baseline and post-intervention. The study hypothesizes that the addition of PNE will produce greater reductions in fear-avoidance beliefs and pain intensity compared to exercise therapy alone.",[68],"Non Specific Low Back Pain",[70,71,72,73,74,75],"Pain","Kinesiophobia","Pain neuroscience education","Core stabilization","Numeric pain rating scale","Fear avoidance belief questionnaire","NOT_YET_RECRUITING","2026-03-04",{"date":79,"type":80},"2026-03-10","ACTUAL",{"date":82,"type":62},"2026-03-02",{"date":84,"type":62},"2026-09-02",{"name":5,"class":6},1]