[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100568309":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":23,"centralContacts":30,"locations":35,"responsibleParty":53,"collaborators":12,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":60,"acronym":12,"eligibilityCriteria":61,"healthyVolunteers":62,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":12,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":75,"overallStatus":37,"whyStopped":12,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"University of Guelph","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Normal sleep","NO_INTERVENTION","During this arm, participants will be asked to come to the lab for testing after a night of normal sleep. Normal sleep will be defined as participants habitual sleep-wake timing.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Partial sleep deprivation","EXPERIMENTAL","During this arm, participants will be asked to come to the lab for testing after a night of partial sleep deprivation. Participants will be asked to fall asleep at their habitual bedtime but wake up early (\\~40% of normal sleep duration).",[18],"Other: Partial sleep deprivation",[20],{"type":6,"name":14,"description":21,"armGroupLabels":22,"otherNames":12},"Participants will be asked to come to the lab for testing after a night of partial sleep deprivation. Participants will be asked to fall asleep at their habitual bedtime but wake up early (\\~40% of normal sleep duration).",[14],[24,27],{"name":25,"affiliation":5,"role":26},"Julian Bommarito, MSc","STUDY_DIRECTOR",{"name":28,"affiliation":5,"role":29},"Philip Millar, PhD","PRINCIPAL_INVESTIGATOR",[31],{"name":25,"role":32,"phone":33,"phoneExt":12,"email":34},"CONTACT","9052209829","jbomma01@uoguelph.ca",[36],{"facility":5,"status":37,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"RECRUITING","Guelph","Ontario","N1G 2W1","Canada","CA",{"type":44,"coordinates":45},"Point",[46,47],-80.25599,43.54594,{"lat":47,"lon":46},[50,51],{"name":25,"role":32,"phone":33,"phoneExt":12,"email":34},{"name":25,"role":52,"phone":12,"phoneExt":12,"email":12},"SUB_INVESTIGATOR",{"type":29,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":12,"oldOrganization":12},"Philip Millar","Associate Professor","100568309","effects-of-partial-sleep-deprivation-on-cardiac-output-during-cycling-100568309",false,"NCT06679543","Effects of Partial Sleep Deprivation on Cardiac Output During Cycling","Inclusion Criteria:\n\n* Free of known cardiovascular or metabolic diseases or sleep disorders\n* No history of smoking (within the past 3 months)\n* Able to engage in physical activity assessed through the physical activity readiness questionnaire (PAR-Q+)\n* No prescription of chronic medications other than oral contraceptives\n* Able to abide by sleep protocols for all visits\n* Individuals who are not allergic to ultrasound gel\n* Individuals who are not pregnant\n\nExclusion Criteria:\n\n* Individuals diagnosed with cardiovascular or metabolic disease or sleep disorders\n* Has a history of smoking (within the past 3 months)\n* Not ready to engage in physical activity as assessed by the PAR-Q+\n* Individuals prescribed chronic medications other than oral contraceptives\n* Unable to abide by sleep protocols for any testing visit\n* Allergic to ultrasound gel\n* Pregnancy",true,"ALL","18 Years","50 Years",{"count":67,"type":68},30,"ESTIMATED","INTERVENTIONAL",[71],"NA","The goal of this clinical trial is to determine if attenuations in cardiac output drive the blunted blood pressure response during cycling exercise following a night of partial sleep deprivation in young healthy adults (%50 females). The secondary outcome is to assess sex differences. The main questions it aims to answer are:\n\n* Do reductions in plasma volume drive reductions in cardiac output and therefore blood pressure during exercise following a night of partial sleep deprivation?\n* Do sex differences exist?\n\nParticipants will:\n\n* Visit the lab after a night of normal sleep and a night of partial sleep deprivation.\n* Keep a daily diary of their sleep and food\u002Fbeverage intake.\n* Perform maximal and submaximal exercise on a cycle ergometer.",[74],"Sleep Deprivation",[76,77,78,79],"exercise blood pressure","cardiac output","plasma volume","sleep deprivation","2026-04-27",{"date":82,"type":83},"2026-04-28","ACTUAL",{"date":85,"type":83},"2025-01-02",{"date":87,"type":68},"2026-12",{"name":5,"class":6},1]