[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100640335":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":34,"responsibleParty":49,"collaborators":19,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":19,"eligibilityCriteria":57,"healthyVolunteers":53,"sex":58,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":19,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":71,"overallStatus":37,"whyStopped":19,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Riphah International University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"photobiomodulation","EXPERIMENTAL","The intervention involves the application of low-level laser therapy (LLLT), also referred to as photobiomodulation (PBM), using a diode laser device with the intensity in the range of 1 to 500 mW . The laser was applied in continuous-wave mode directly to the skin over the knee joint at multiple anatomical points, including the medial, lateral, superior, and inferior aspects of the patella, covering 8 to 9 specific locations. Total treatment time will be 10 minutes, delivered with a spot size 13 Effects of Photobiomodulation o knee hemarthosis in children with Hemophilia ranging from 0.04 to 0.07 cm². During the procedure, patients are positioned in a supine posture with the knee slightly flexed (20-30°) to allow optimal access to the target areas.",[13],"Radiation: photobiomodulation",[15],{"type":16,"name":9,"description":17,"armGroupLabels":18,"otherNames":19},"RADIATION","Photobiomodulation is a non-invasive therapy that uses low-level light (typically from lasers or LEDs) to stimulate cellular activity and promote healing. It works by enhancing mitochondrial function, increasing energy (ATP) production, and reducing inflammation. This therapy is commonly used for pain relief, tissue repair, and improving recovery in various clinical conditions.",[9],null,[21],{"name":22,"affiliation":5,"role":23},"Zaira Zeeshan, MS","PRINCIPAL_INVESTIGATOR",[25,30],{"name":26,"role":27,"phone":28,"phoneExt":19,"email":29},"Imran Amjad, PhD","CONTACT","03324390125","imran.amjad@riphah.edu.pk",{"name":31,"role":27,"phone":32,"phoneExt":19,"email":33},"Muhammad Asif Javed, PhD*","+923224209422","a.javed@riphah.edu.pk",[35],{"facility":36,"status":37,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":19},"Sundas Foundation","RECRUITING","Sialkot","Punjab Province","5100","Pakistan","PK",{"type":44,"coordinates":45},"Point",[46,47],74.53134,32.49268,{"lat":47,"lon":46},{"type":50,"investigatorFullName":19,"investigatorTitle":19,"investigatorAffiliation":19,"oldNameTitle":19,"oldOrganization":19},"SPONSOR","100640335","effects-of-photobiomodulation-in-hemophilia-patients-100640335",false,"NCT07579585","Effects of Photobiomodulation in Hemophilia Patients.","Effects of Photobiomodulation on Knee Hemarthosis in Patients With Hemophilia.","Inclusion Criteria:\n\n* Hemophilia patients with knee hemarthosis\n* Patients of age 9-14 yrs will be taken\n* Bothmaleand female population will be included\n\nExclusion Criteria:\n\n* Presence of open wounds at or near the treatment site.\n* Kneejoint subluxation.\n* Presence of congenital or acquired skeletal deformities.\n* Children diagnosed with cardiopulmonary dysfunctions.\n* Children with neurological deficits","ALL","9 Years","14 Years",{"count":62,"type":63},24,"ESTIMATED","INTERVENTIONAL",[66],"NA","Hemophilia is a genetic bleeding disorder that commonly leads to knee hemarthrosis, causing pain, swelling, and reduced joint mobility in children. While standard treatments include clotting factor replacement and physiotherapy, additional non-invasive approaches are being explored. This study aims to evaluate the effects of photobiomodulation on knee hemarthrosis in male hemophilia patients aged 9-14 years. It focuses on determining whether this therapy can reduce pain and swelling and improve joint range of motion when used alongside",[69,70],"Hemarthrosis, Knee","Hemophilia",[72,73,70],"Photobiomodulation","Hemarthrosis","2026-05-05",{"date":76,"type":77},"2026-05-12","ACTUAL",{"date":79,"type":77},"2026-04-05",{"date":81,"type":63},"2026-07-10",{"name":5,"class":6},1]