[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100633262":3},{"organization":4,"armGroups":7,"interventions":31,"overallOfficials":43,"centralContacts":47,"locations":53,"responsibleParty":72,"collaborators":30,"id":75,"slug":76,"hasResults":77,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":81,"eligibilityCriteria":82,"healthyVolunteers":83,"sex":84,"minAge":30,"maxAge":30,"enrollmentInfo":85,"targetDuration":30,"studyType":88,"phases":89,"briefSummary":91,"conditions":92,"keywords":94,"overallStatus":56,"whyStopped":30,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":109},{"fullName":5,"class":6},"Universidad Rey Juan Carlos","OTHER",[8,14,20,26],{"label":9,"type":10,"description":11,"interventionNames":12},"realtDCS&exercise Group","EXPERIMENTAL","24 sessions of reactive exercise simulatenously with anodal tDCS over the motor cortex contralteral to the most affected side.",[13],"Other: real tDCS and exercise",{"label":15,"type":16,"description":17,"interventionNames":18},"shamtDCS&exercise Group","PLACEBO_COMPARATOR","24 sessions of reactive exercise simulatenously with sham tDCS over the motor cortex contralteral to the most affected side.",[19],"Other: Sham tDCS and exercise",{"label":21,"type":22,"description":23,"interventionNames":24},"Exercise Group","ACTIVE_COMPARATOR","24 sessions of reactive exercise.",[25],"Other: Exercise",{"label":27,"type":28,"description":29,"interventionNames":30},"Control Group","NO_INTERVENTION","No interventio. Only evaluations before and after 5 weeks time.",null,[32,35,39],{"type":6,"name":33,"description":11,"armGroupLabels":34,"otherNames":30},"real tDCS and exercise",[9],{"type":6,"name":36,"description":37,"armGroupLabels":38,"otherNames":30},"Sham tDCS and exercise","24 sessions of reactive exercise with sham tDCS",[15],{"type":6,"name":40,"description":41,"armGroupLabels":42,"otherNames":30},"Exercise","24 sessions of reactive exercise",[21],[44],{"name":45,"affiliation":5,"role":46},"Miguel Angel Fernández del Olmo, PhD","PRINCIPAL_INVESTIGATOR",[48],{"name":49,"role":50,"phone":51,"phoneExt":30,"email":52},"Eduardo Villamil Cabell, PhD","CONTACT","+34 666 66 81 05","eduardo.villamil@urjc.es",[54],{"facility":55,"status":56,"city":57,"state":58,"zip":59,"country":60,"countryCode":61,"cosmosGeoPoint":62,"geoPoint":67,"contacts":68},"Center of Sport Research","RECRUITING","Fuenlabrada","Madrid","28992","Spain","ES",{"type":63,"coordinates":64},"Point",[65,66],-3.79415,40.28419,{"lat":66,"lon":65},[69],{"name":45,"role":50,"phone":70,"phoneExt":30,"email":71},"600077866","miguel.delolmo@urjc.es",{"type":46,"investigatorFullName":73,"investigatorTitle":74,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"Miguel Fernández del Olmo","Professor","100633262","effects-of-physical-exercise-combined-with-transcranial-direct-current-stimulation-in-parkinsons-disease-100633262",false,"NCT07524400","Effects of Physical Exercise Combined With Transcranial Direct Current Stimulation in Parkinson's Disease","Effects of the Combination of Physical Exercise and Transcranial Direct Current Stimulation on Motor Function and Underlying Neurophysiological Mechanisms in Parkinson's Disease","ExtDCSPARK","Inclusion Criteria:\n\nClinical diagnosis of idiopathic Parkinson's disease, established according to the UK Parkinson's Disease Society Brain Bank Criteria.\n\nAbility to understand and comply with study procedures.\n\nStable antiparkinsonian medication regimen prior to study participation.\n\nExclusion Criteria:\n\nSignificant cognitive impairment, defined as a score \\\u003C 23 on the Mini-Mental State Examination (MMSE).\n\nBelow-average premorbid intelligence, defined as a score \\\u003C 40 on the Vocabulary subtest of the Wechsler Adult Intelligence Scale - Third Edition (WAIS-III).\n\nClinically significant depression, defined as a score \\> 10 on the Geriatric Depression Scale (GDS-15).\n\nCurrent treatment with cholinesterase inhibitors.\n\nPresence of severe cardiovascular disease, including but not limited to:\n\nCongestive heart failure\n\nIschemic heart disease\n\nCardiac pacemaker\n\nOrthostatic hypotension\n\nUncontrolled diabetes mellitus.\n\nHistory of stroke or traumatic brain injury.\n\nHistory of seizure disorder or epilepsy.\n\nPresence or prior implantation of a deep brain stimulation (DBS) device.\n\nHistory of major orthopedic surgery that could interfere with motor performance or gait.\n\nPresence of implanted electronic devices, including cardiac pacemakers, incompatible with study procedures.",true,"ALL",{"count":86,"type":87},100,"ESTIMATED","INTERVENTIONAL",[90],"NA","A controlled, blinded, and randomized clinical study will be carried out in a large sample of people with Parkinson's disease, where the combined effects of physical exercise and transcranial direct curren stimlation (tDCS) on motor function will be evaluated.",[93],"Parkinson' Disease",[95,96,97,98,99],"exercises training","transcranial direct electrical stimulation","cue training","cortical excitability","Transcranial Magnetic Stimulation","2026-04-06",{"date":102,"type":103},"2026-04-13","ACTUAL",{"date":105,"type":87},"2026-05-10",{"date":107,"type":87},"2026-08-30",{"name":5,"class":6},1]