[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100642530":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":37,"locations":45,"responsibleParty":75,"collaborators":26,"id":77,"slug":78,"hasResults":79,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":26,"eligibilityCriteria":83,"healthyVolunteers":84,"sex":85,"minAge":86,"maxAge":87,"enrollmentInfo":88,"targetDuration":26,"studyType":91,"phases":92,"briefSummary":94,"conditions":95,"keywords":98,"overallStatus":108,"whyStopped":26,"lastUpdateSubmitDate":109,"lastUpdatePostDateStruct":110,"startDateStruct":113,"completionDateStruct":115,"leadSponsor":117,"locationsCount":118},{"fullName":5,"class":6},"Vrije Universiteit Brussel","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Manual Abdominal Mobilization","EXPERIMENTAL","Participants receive standardized abdominal manual mobilization techniques applied by a physiotherapist, once per week over three menstrual cycles. Session duration: 20 min",[13],"Procedure: Abdominal manual mobilization",{"label":15,"type":16,"description":17,"interventionNames":18},"Sham Manual Therapy","SHAM_COMPARATOR","Participants receive superficial manual contact in the same anatomical regions without therapeutic intent or pressure, once per week over three menstrual cycles. Session duration matches the experimental group.",[19],"Procedure: Sham manual contact",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Abdominal manual mobilization","Abdominal mobilization (10 min): Patient supine, knees flexed. Therapist's ulnar hand borders placed on lower abdomen. During expiration, a cranial manual push is applied following the respiratory cycle; the maneuver is repeated during inspiration. Hands are then placed over the lower ribs at the diaphragmatic domes; a caudal push is applied during inspiration and repeated during expiration.\n\nBroad ligament mobilization (5 min): Patient supine, knees flexed. Therapist's cephalad hand placed over broad ligament landmarks; other hand holds the patient's legs. Opposing hand movements create an abdominal stretch. Lateral uterine mobilizations performed abdominally on both sides.\n\nHypopressive abdominal exercises (5 min): Therapist guides patient through hypopressive technique: exhale, breath-hold, false thoracic inspiration, abdominal draw-in, transverse abdominis contraction. Hold 10 seconds, then release. Position: standing, knees flexed, hands pressing on thighs.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Sham manual contact","Superficial skin contact applied to the abdominal region without therapeutic pressure or mobilization, intended to mimic the experimental intervention in terms of time and positioning.",[15],[32,35],{"name":33,"affiliation":5,"role":34},"Steven Provyn, PhD","STUDY_CHAIR",{"name":36,"affiliation":5,"role":34},"Bart Roelands, PhD",[38,43],{"name":39,"role":40,"phone":41,"phoneExt":26,"email":42},"Barnavol Aurélie","CONTACT","+32486714996","aurelie.barnavol@vub.be",{"name":33,"role":40,"phone":44,"phoneExt":26,"email":26},"+32475454214",[46,65],{"facility":5,"status":26,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"Brussels","Brussels Capital","1090","Belgium","BE",{"type":53,"coordinates":54},"Point",[55,56],4.34878,50.85045,{"lat":56,"lon":55},[59,63],{"name":60,"role":40,"phone":61,"phoneExt":26,"email":62},"Steven Prof. Provyn, PhD","+475454214","steven.Provyn@vub.be",{"name":64,"role":40,"phone":41,"phoneExt":26,"email":42},"Aurélie Barnavol",{"facility":66,"status":26,"city":47,"state":48,"zip":67,"country":50,"countryCode":51,"cosmosGeoPoint":68,"geoPoint":70,"contacts":71},"Isek He2B","1160",{"type":53,"coordinates":69},[55,56],{"lat":56,"lon":55},[72,73],{"name":64,"role":40,"phone":41,"phoneExt":26,"email":42},{"name":60,"role":40,"phone":44,"phoneExt":26,"email":74},"steven.provyn@vub.be",{"type":76,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100642530","effects-of-physiotherapy-on-ultrasound-and-clinical-parameters-in-women-with-dysmenorrhea-100642530",false,"NCT07645196","Effects of Physiotherapy on Ultrasound and Clinical Parameters in Women With Dysmenorrhea","Effects of Physiotherapy on Ultrasound and Clinical Parameters in Women With Dysmenorrhea With or Without Endometriosis","Inclusion Criteria:\n\n* female sex\n* aged 18 to 50 years\n* clinical diagnosis of dysmenorrhea (cyclic pelvic pain during menstruation)\n\nExclusion Criteria:\n\n* Pregnancy or breastfeeding\n* Delivery less than 1 year prior to enrollment\n* History of abdominal or pelvic surgery within the past 3 months\n* Diagnosis of fibromyalgia, diabetes, or cancer\n* Ongoing manual therapy treatment of the abdominal or genital area",true,"FEMALE","18 Years","50 Years",{"count":89,"type":90},80,"ESTIMATED","INTERVENTIONAL",[93],"NA","Dysmenorrhea affects up to 90% of women of reproductive age and represents a significant public health concern. Beyond prostaglandin-mediated uterine contractions, dysmenorrhea involves central sensitization mechanisms and myofascial components, including abdominal trigger points. Despite growing interest in physiotherapy for chronic pelvic pain, objective data on tissue-level changes induced by manual therapy remain scarce.\n\nThis randomized single-blind sham-controlled trial aims to evaluate the effects of abdominal manual mobilization techniques on (1) tissue stiffness measured by shear wave elastography at the uterine cervix and bilateral abdominal regions, and (2) clinical outcomes including pain intensity and quality of life in women with dysmenorrhea, with or without endometriosis.\n\nParticipants will be randomly assigned to either a treatment group receiving standardized abdominal manual therapy or a sham group receiving superficial manual contact. Assessments will be conducted over three menstrual cycles using shear wave elastography, the Numeric Rating Scale (NRS), and the SF-36 questionnaire.",[96,97],"Dysmenorrhea","Endometriosis",[96,99,100,101,102,103,104,105,106,107],"endometriosis","Shear wave elastography","Manual therapy","Physiotherapy","Abdominal mobilization","Tissue stiffness","Chronic pelvic pain","Central sensitization","Menstrual pain","NOT_YET_RECRUITING","2026-06-08",{"date":111,"type":112},"2026-06-12","ACTUAL",{"date":114,"type":90},"2026-09",{"date":116,"type":90},"2028-09",{"name":5,"class":6},2]