[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100590627":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":34,"centralContacts":38,"locations":45,"responsibleParty":61,"collaborators":63,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":29,"eligibilityCriteria":73,"healthyVolunteers":74,"sex":75,"minAge":76,"maxAge":77,"enrollmentInfo":78,"targetDuration":29,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":29,"overallStatus":47,"whyStopped":29,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Chung Shan Medical University","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Placebo","PLACEBO_COMPARATOR","The composition of placebo capsules is same as the experimental capsules, except that they don't contain probiotics.",[13],"Dietary Supplement: Placebo",{"label":15,"type":16,"description":17,"interventionNames":18},"Low dose of ABKefir","EXPERIMENTAL","Low dose of probiotics, 5×10\\^9 CFU\u002Fcapsule",[19],"Dietary Supplement: Probiotics (ABKefir)",{"label":21,"type":16,"description":22,"interventionNames":23},"High dose of ABKefir","High dose of probiotics, 1×10\\^10 CFU\u002Fcapsule",[19],[25,30],{"type":26,"name":9,"description":27,"armGroupLabels":28,"otherNames":29},"DIETARY_SUPPLEMENT","Take a capsule of placebo within 30 minutes after breakfast, and once a day.",[9],null,{"type":26,"name":31,"description":32,"armGroupLabels":33,"otherNames":29},"Probiotics (ABKefir)","Take a capsule of ABKefir within 30 minutes after breakfast, and once a day.",[21,15],[35],{"name":36,"affiliation":5,"role":37},"Hsin-Chi Pan, MS student","PRINCIPAL_INVESTIGATOR",[39],{"name":40,"role":41,"phone":42,"phoneExt":43,"email":44},"Chin-Lin Hsu, Professor","CONTACT","04-24730022","12222","clhsu@csmu.edu.tw",[46],{"facility":5,"status":47,"city":48,"state":49,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"RECRUITING","Taichung","South","402","Taiwan","TW",{"type":54,"coordinates":55},"Point",[56,57],120.6839,24.1469,{"lat":57,"lon":56},[60],{"name":40,"role":41,"phone":42,"phoneExt":43,"email":44},{"type":62,"investigatorFullName":29,"investigatorTitle":29,"investigatorAffiliation":29,"oldNameTitle":29,"oldOrganization":29},"SPONSOR",[64],{"name":65,"class":66},"SYNBIO TECH INC. Kaohsiung Taiwan","UNKNOWN","100590627","effects-of-probiotics-on-symptoms-of-constipation-in-adults-with-functional-constipation-100590627",false,"NCT06969872","Effects of Probiotics on Symptoms of Constipation in Adults With Functional Constipation","The Effects of ABKefir on Functional Constipation in Subjects: a Randomized, Double-blind, Placebo-controlled Trial","Inclusion Criteria:\n\n* male or female\n* aged 18-75 years old\n* fulfill Rome IV criteria for functional constipation\n* have not participated in similar research in the past three months\n\nExclusion Criteria:\n\n* Personal or family history of colon cancer, celiac disease, and inflammatory bowel disease\n* Irritable bowel syndrome diagnosed during colonoscopy\n* Those who are pregnant recently (including men and women), or are pregnant or breastfeeding women.\n* Taking antidepressants, anti-anxiety drugs and other psychotropic drugs.\n* Long-term medication is required to improve constipation\n* Those diagnosed with myocardial infarction, cerebral infarction, malignant tumor and\u002For other serious diseases are not suitable for participating in the study.\n* Allergic symptoms to probiotics or any ingredients\n* Having a history of serious mental illness\n* Drug-related crimes or alcohol problems\n* Have recently traveled to areas where parasitic diseases are prevalent.",true,"ALL","18 Years","75 Years",{"count":79,"type":80},165,"ESTIMATED","INTERVENTIONAL",[83],"NA","The purpose of this study was to evaluate the efficacy of 1 capsules of ABKefir per day on symptoms of constipation in subjects with functional constipation by clinical trial.",[86],"Functional Constipation (FC)","2025-12-29",{"date":89,"type":90},"2026-01-02","ACTUAL",{"date":92,"type":90},"2024-12-27",{"date":94,"type":80},"2026-09-30",{"name":5,"class":6},1]