[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100639653":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":28,"centralContacts":32,"locations":38,"responsibleParty":58,"collaborators":25,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":64,"acronym":25,"eligibilityCriteria":65,"healthyVolunteers":62,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":25,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":79,"overallStatus":41,"whyStopped":25,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Universidade Federal Fluminense","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Royal Jelly + Propolis Group","EXPERIMENTAL","Participants will receive 4 capsules per day, providing the dosage of 300mg of royal jelly + 500mg propolis for 2 months (8 weeks).",[13],"Dietary Supplement: Royal Jelly + Propolis Group",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo Group","PLACEBO_COMPARATOR","The placebo group will receive 4 capsules per day (containing microcrystalline cellulose and magnesium stearate in colored gelatin capsules capable of masking the appearance of the internal content), at the same time for 2 months.",[19],"Dietary Supplement: Placebo",[21,26],{"type":22,"name":23,"description":17,"armGroupLabels":24,"otherNames":25},"DIETARY_SUPPLEMENT","Placebo",[15],null,{"type":22,"name":9,"description":11,"armGroupLabels":27,"otherNames":25},[9],[29],{"name":30,"affiliation":5,"role":31},"Ludmila Cardozo, PhD","STUDY_DIRECTOR",[33],{"name":34,"role":35,"phone":36,"phoneExt":25,"email":37},"Denise Mafra, PhD","CONTACT","+5521985683003","dmafra30@gmail.com",[39],{"facility":40,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Denise Mafra","RECRUITING","Niterói","Rio de Janeiro","24220-900","Brazil","BR",{"type":48,"coordinates":49},"Point",[50,51],-43.10361,-22.88333,{"lat":51,"lon":50},[54],{"name":55,"role":35,"phone":56,"phoneExt":25,"email":57},"Ludmila cardozo","+55987333185","ludmilacardozo@id.uff.br",{"type":59,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100639653","effects-of-propolis-and-royal-jelly-supplementation-on-inflammatory-and-oxidative-stress-markers-in-patients-with-systemic-arterial-hypertension-100639653",false,"NCT07596966","EFFECTS OF PROPOLIS AND ROYAL JELLY SUPPLEMENTATION ON INFLAMMATORY AND OXIDATIVE STRESS MARKERS IN PATIENTS WITH SYSTEMIC ARTERIAL HYPERTENSION","Inclusion Criteria:\n\n* Diagnosis of stage 1 and 2 hypertension\n* Regular treatment for more than 6 months\n* There have been no changes in medication doses over the last three months.\n\nExclusion Criteria:\n\n* Autoimmune and infectious diseases, diabetes\n* Chronic kidney disease, liver disease, cancer and AIDS\n* Pregnant women\n* Use of catabolic drugs or antibiotics\n* Use of antioxidant vitamin supplements, prebiotics, probiotics, symbiotic\n* Habitual intake of royal jelly and propolis","ALL","18 Years","75 Years",{"count":70,"type":71},48,"ESTIMATED","INTERVENTIONAL",[74],"NA","The study aims to evaluate the effect of the royal jelly and propolis on inflammation and oxidative stress in participants with systemic arterial hypertension. A longitudinal double-blind randomized clinical trial will be carried out, involving hypertensive participants for two months.",[77,78],"Systemic Arterial Hypertension","Inflammation",[80,81,82,83,84],"inflammation","royal jelly","propolis","hypertension","oxidative stress","2026-05-12",{"date":87,"type":88},"2026-05-19","ACTUAL",{"date":90,"type":88},"2025-10-15",{"date":92,"type":71},"2027-12-10",{"name":5,"class":6},1]