[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100637767":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":15,"locations":21,"responsibleParty":40,"collaborators":10,"id":43,"slug":44,"hasResults":45,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":10,"eligibilityCriteria":49,"healthyVolunteers":45,"sex":50,"minAge":51,"maxAge":10,"enrollmentInfo":52,"targetDuration":10,"studyType":55,"phases":10,"briefSummary":56,"conditions":57,"keywords":10,"overallStatus":60,"whyStopped":10,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":70},{"fullName":5,"class":6},"Chinese Academy of Medical Sciences, Fuwai Hospital","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Remimazolam",null,"General anesthesia is remimazolam-based, combined with other intravenous agents.",{"label":13,"type":10,"description":14,"interventionNames":10},"Control","General anesthesia is propofol-based, combined with other intravenous agents.",[16],{"name":17,"role":18,"phone":19,"phoneExt":10,"email":20},"Jia Shi, M.D.","CONTACT","+86 10 88322467","shijia@fuwai.com",[22],{"facility":23,"status":10,"city":24,"state":25,"zip":26,"country":27,"countryCode":28,"cosmosGeoPoint":29,"geoPoint":34,"contacts":35},"State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College","Beijing","Beijing Municipality","100037","China","CN",{"type":30,"coordinates":31},"Point",[32,33],116.39723,39.9075,{"lat":33,"lon":32},[36,38],{"name":17,"role":18,"phone":37,"phoneExt":10,"email":20},"86 10 88322467",{"name":17,"role":39,"phone":10,"phoneExt":10,"email":10},"PRINCIPAL_INVESTIGATOR",{"type":39,"investigatorFullName":41,"investigatorTitle":42,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SHI Jia","Vice Chair, Department of Anesthesiology","100637767","effects-of-remimazolam-on-neurocognitive-function-in-patients-undergoing-cardiovascular-surgery-100637767",false,"NCT07598019","Effects of Remimazolam on Neurocognitive Function in Patients Undergoing Cardiovascular Surgery","Effects of Remimazolam on Neurocognitive Function in Patients Undergoing Cardiovascular Surgery (the EFFICACY Study)","Inclusion Criteria:\n\n1. Male or female adult patients aged 60 years or older\n2. Receiving elective cardiovascular surgery with cardiopulmonary bypass\n3. Written Informed consent provided\n\nExclusion Criteria:\n\n1. Deep hypothermia circulatory arrest\n2. Breastfeeding or pregnancy\n3. Mental or legal disability\n4. Terminal illness with a life expectancy of less than 3 months\n5. Unable to receive neuro-cognitive evaluation due to language, vision, or hearing impairments","ALL","60 Years",{"count":53,"type":54},210,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to explore the effect of remimazolam-based total intravenous anesthesia on postoperative neurocognitive function in patients who undergo cardiovascular surgery.\n\nThe main question this study tries to answer is: Does remimazolam influence the incidence of postoperative delirium in cardiovascular surgery? Participants already apply remimazolam-based total intravenous anesthesia as part of their regular medical treatment for general anesthesia to perform cardiac surgery will answer questionnaires about cognitive function after surgery.",[58,59],"Neurocognitive Disorder","Cardiac Surgery","NOT_YET_RECRUITING","2026-05-13",{"date":63,"type":64},"2026-05-20","ACTUAL",{"date":66,"type":54},"2026-06-15",{"date":68,"type":54},"2027-12-30",{"name":5,"class":6},1]