[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100640646":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":33,"locations":42,"responsibleParty":58,"collaborators":60,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":70,"acronym":25,"eligibilityCriteria":71,"healthyVolunteers":68,"sex":72,"minAge":73,"maxAge":25,"enrollmentInfo":74,"targetDuration":25,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":85,"overallStatus":91,"whyStopped":25,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"Universidade Federal Fluminense","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Propolis + Royal jelly Group","EXPERIMENTAL","They will receive 4 capsules per day, providing 300 mg of royal jelly per day and 500 mg of propolis per day.",[13],"Dietary Supplement: Propolis + Royal Jelly",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo Group","PLACEBO_COMPARATOR","They will receive 4 capsules per day, providing daily delivery of the active formulation vehicle (microcrystalline cellulose and magnesium stearate in colored gelatin capsules capable of masking the appearance of the internal contents).",[19],"Dietary Supplement: Placebo",[21,26],{"type":22,"name":23,"description":11,"armGroupLabels":24,"otherNames":25},"DIETARY_SUPPLEMENT","Propolis + Royal Jelly",[9],null,{"type":22,"name":27,"description":17,"armGroupLabels":28,"otherNames":25},"Placebo",[15],[30],{"name":31,"affiliation":5,"role":32},"Ludmila Cardozo","PRINCIPAL_INVESTIGATOR",[34,39],{"name":35,"role":36,"phone":37,"phoneExt":25,"email":38},"Denise Mafra","CONTACT","+5521985683003","dmafra30@gmail.com",{"name":31,"role":36,"phone":40,"phoneExt":25,"email":41},"+5521987333185","ludmilacardozo@id.uff.br",[43],{"facility":44,"status":25,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"Denise mafra","Niterói","Rio de Janeiro","24220-900","Brazil","BR",{"type":51,"coordinates":52},"Point",[53,54],-43.10361,-22.88333,{"lat":54,"lon":53},[57],{"name":31,"role":36,"phone":40,"phoneExt":25,"email":41},{"type":59,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR",[61,64],{"name":62,"class":63},"Conselho Nacional de Desenvolvimento Científico e Tecnológico","OTHER_GOV",{"name":65,"class":63},"Rio de Janeiro State Research Supporting Foundation (FAPERJ)","100640646","effects-of-royal-jelly-and-propolis-on-metabolomic-signatures-inflammation-and-cardiovascular-risk-in-patients-with-coronary-artery-disease-100640646",false,"NCT07596992","Effects of Royal Jelly and Propolis on Metabolomic Signatures, Inflammation, and Cardiovascular Risk in Patients With Coronary Artery Disease.","Inclusion Criteria:\n\n* Both sexes\n* Over 18 years of age;\n* Diagnosed with Coronary Artery Disease: confirmed by coronary angiography, coronary computed tomography angiography, or functional testing with ischemic load);\n* Participants who are asymptomatic or have angina limited to functional class III will be considered;\n* Patients who have already undergone coronary revascularization and angioplasty may participate;\n* the last acute coronary event must have occurred more than one year ago.\n\nExclusion Criteria:\n\n* Unstable Coronary Artery Disease;\n* Pre-operative coronary artery bypass grafting or awaiting elective angioplasty;\n* Unstable angina;\n* NYHA functional class III or higher;\n* Advanced chronic kidney disease (creatinine clearance \\\u003C 30 ml\u002Fmin\u002F1.73 m²);\n* Individuals with autoimmune diseases.","ALL","18 Years",{"count":75,"type":76},50,"ESTIMATED","INTERVENTIONAL",[79],"NA","The aim of this project is to evaluate the effect of bioactive compound sources, propolis and royal jelly, on metabolomics, inflammation, and cardiovascular risk markers in participants with coronary artery disease. A longitudinal double-blind randomized clinical trial will be carried out, involving CAD participants for two months.",[82,83,84],"Coronary Artery Disease (CAD)","Oxidative Stress","Inflammation",[86,87,88,89,90],"royal jelly","propolis","coronary artery disease","oxidative stress","inflammation","NOT_YET_RECRUITING","2026-05-12",{"date":94,"type":95},"2026-05-19","ACTUAL",{"date":97,"type":76},"2026-05-18",{"date":99,"type":76},"2028-12",{"name":5,"class":6},1]