[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100507160":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":32,"centralContacts":33,"locations":44,"responsibleParty":58,"collaborators":32,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":32,"eligibilityCriteria":68,"healthyVolunteers":64,"sex":69,"minAge":70,"maxAge":32,"enrollmentInfo":71,"targetDuration":32,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":80,"overallStatus":83,"whyStopped":32,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"The First Hospital of Jilin University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"rTMS","ACTIVE_COMPARATOR","Patients are treated with repetitive transcranial magnetic stimulation (rTMS).",[13],"Device: Repetitive Transcranial Magnetic Stimulation",{"label":15,"type":16,"description":17,"interventionNames":18},"sham-rTMS","SHAM_COMPARATOR","Patients are treated with sham repetitive transcranial magnetic stimulation (sham-rTMS).",[19],"Device: Sham Repetitive Transcranial Magnetic Stimulation",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Repetitive Transcranial Magnetic Stimulation","rTMS is applied using a transcranial magnetic stimulator with a figure-of-8 coil once per day for 10 consecutive days. rTMS is delivered to the right dorsolateral prefrontal cortex (DLPFC) at a frequency of 1 Hz for 20 minutes (1200 total pulses).",[9],[9],{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"Sham Repetitive Transcranial Magnetic Stimulation","Sham-rTMS is performed in the same way as the treatment group except that the coil is rotated 90° away from the scalp.",[15],[15],null,[34,40],{"name":35,"role":36,"phone":37,"phoneExt":38,"email":39},"Yi Yang, MD, PhD","CONTACT","13756661217","0086","doctor_yangyi@163.com",{"name":41,"role":36,"phone":42,"phoneExt":38,"email":43},"Zhen-Ni Guo, MD, PhD","18186872986","zhen1ni2@163.com",[45],{"facility":46,"status":32,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":32},"First Hospital of Jilin University","Changchun","Jilin","130000","China","CN",{"type":53,"coordinates":54},"Point",[55,56],125.32278,43.88,{"lat":56,"lon":55},{"type":59,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":32,"oldOrganization":32},"SPONSOR_INVESTIGATOR","Yi Yang","Vice President of First Hospital of Jilin University","100507160","effects-of-rtms-on-the-anxiety-state-of-older-patients-with-gad-100507160",false,"NCT05883774","Effects of rTMS on the Anxiety State of Older Patients With GAD","Effects of Repetitive Transcranial Magnetic Stimulation on the Anxiety State of Older Patients With Generalized Anxiety Disorder","Inclusion Criteria:\n\n* 1）Age≥60 years, regardless of gender.\n* 2）Meets the diagnostic criteria for generalized anxiety disorder in the Diagnostic and Statistical Manual of Mental Disorders Fifth Edition (DSM-V) developed by the American Psychiatric Association.\n* 3）HAMA score≥14 and HAMD-17 items score \\\u003C17.\n* 4）No adjustment in the type and dose of anti-anxiety medication in the 3 months prior to randomization.\n* 5）Willing to participate and sign the informed consent.\n\nExclusion Criteria:\n\n* 1）Traumatic brain injury or other conditions affecting the brain, such encephalitis, brain tumors, or intracranial hypertension.\n* 2）Previous history of epilepsy, family history of epilepsy or presence of seizure provoking factors or alcohol abuse.\n* 3）History of other psychiatric disorders such as current post-traumatic stress disorder, substance use disorder (within 6 months), bipolar disorder and obsessive-compulsive disorder.\n* 4）Unstable mental state with impulses toward self-harm or suicide.\n* 5）Presence of intracranial metal implant, cochlear implant, built-in pulse generator (such as cardiac pacemaker), etc.\n* 6）Medical or surgical disorders that are severe or unstable.\n* 7）Pregnancy or breastfeeding.\n* 8\\) Those who are participating in other clinical research or has participated in other clinical research or has participated in this study within 3 months prior to enrollment.\n* 9\\) Other conditions that the researchers think are not suitable for the project.","ALL","60 Years",{"count":72,"type":73},100,"ESTIMATED","INTERVENTIONAL",[76],"NA","The purpose of this study is to evaluate the effects of low-frequency repetitive transcranial magnetic stimulation on anxiety state in older patients with generalized anxiety disorder.",[79],"Generalized Anxiety Disorder",[81,82],"repetitive transcranial magnetic stimulation","generalized anxiety disorder","NOT_YET_RECRUITING","2024-10-01",{"date":86,"type":87},"2024-10-02","ACTUAL",{"date":89,"type":73},"2024-12-01",{"date":91,"type":73},"2025-12-01",{"name":60,"class":6},1]