[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100573612":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":10,"centralContacts":10,"locations":24,"responsibleParty":36,"collaborators":10,"id":40,"slug":41,"hasResults":42,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":10,"eligibilityCriteria":46,"healthyVolunteers":42,"sex":47,"minAge":48,"maxAge":49,"enrollmentInfo":50,"targetDuration":10,"studyType":53,"phases":10,"briefSummary":54,"conditions":55,"keywords":58,"overallStatus":60,"whyStopped":10,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":70},{"fullName":5,"class":6},"Umraniye Education and Research Hospital","OTHER_GOV",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"1",null,"Group pre-incisional: received 0.5% 20 ml bupivacaine preincisional before the nail head was placed",[13],"Procedure: scalp nerve block",{"label":15,"type":10,"description":16,"interventionNames":17},"2","Group post-incisional: received 0.5% 20 ml bupivacaine postcisional after the skin incision was closed",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"PROCEDURE","scalp nerve block","scalp nerve block is performed bilaterally by an anesthesiologist after induction of anesthesia and 5 minutes before head immobilization, according to the technique described by Pinosky et al. Prepare a syringe (20 mL) for scalp blocks. It is performed using 0.35% bupivacaine and 5 mcg epinephrine (1:2,000,000) using a 23-gauge needle inserted at a 45° angle to the skin and penetrating deeply into the outer edge of the scalp.",[9,15],[25],{"facility":5,"status":10,"city":26,"state":27,"zip":28,"country":29,"countryCode":10,"cosmosGeoPoint":30,"geoPoint":35,"contacts":10},"Istanbul","Umraniye","34734","Turkey (Türkiye)",{"type":31,"coordinates":32},"Point",[33,34],28.94966,41.01384,{"lat":34,"lon":33},{"type":37,"investigatorFullName":38,"investigatorTitle":39,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Zeliha Alicikus","Head of Anesthesia and reanimation","100573612","effects-of-scalp-nerve-block-on-postoperative-pain-hemodynamics-and-surgical-stress-response-in-craniotomy-surgery-100573612",false,"NCT06748547","Effects of Scalp Nerve Block on Postoperative Pain, Hemodynamics and Surgical Stress Response in Craniotomy Surgery","Effects of Scalp Nerve Block on Postoperative Pain, Hemodynamics and Surgical","Inclusion Criteria:\n\n* Age range 18-65\n* ASA 1-3 score\n\nExclusion Criteria:\n\n* Chronic hypertension\n* Arrhythmia\n* body mass index (BMI) over 40 kg\u002Fm2\n* Bleeding diathesis\n* Allergy\n* Serious cardiovascular, pulmonary, renal and hepatic disease\n* Local infection at the injection site\n* Alcohol and substance abuse\n* Neurological sequelae, mental retardation\n* GCS under 15\n* Patients admitted to the intensive care unit as intubated\n* Pregnancy\n* Those with a history of chronic pain\n* Scalp infection\n* Use of vozoactive drugs\n* Patients with previous craniotomy\n* Patients who do not accept","ALL","18 Years","65 Years",{"count":51,"type":52},64,"ESTIMATED","OBSERVATIONAL","The hypothesis of this study is that preincisional scalp nerve block will reduce postoperative opioid use and surgical stress response compared to postincisional scalp nerve block in craniotomy surgery with general anesthesia.",[56,57],"Analgesia","Post Operative Pain",[59],"scalp nerve block,Craniotomy,postoperative pain","NOT_YET_RECRUITING","2025-11-16",{"date":63,"type":64},"2025-11-19","ACTUAL",{"date":66,"type":52},"2025-11-30",{"date":68,"type":52},"2026-05-01",{"name":5,"class":6},1]