[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100611654":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":33,"centralContacts":38,"locations":48,"responsibleParty":67,"collaborators":28,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":28,"eligibilityCriteria":76,"healthyVolunteers":72,"sex":77,"minAge":78,"maxAge":79,"enrollmentInfo":80,"targetDuration":28,"studyType":83,"phases":84,"briefSummary":86,"conditions":87,"keywords":89,"overallStatus":98,"whyStopped":28,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":108},{"fullName":5,"class":6},"Lincoln University College","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Intra articular steroid injection","EXPERIMENTAL","Participants will receive intra-articular injections of corticosteroid such as methylprednisolone in order to reduce inflammation and manage pain.",[13],"Procedure: Intra articular steroid injection",{"label":15,"type":10,"description":16,"interventionNames":17},"Intra articular PRP","Participants will receive PRP, derived from the own blood of patient, which will be processed in laboratory to concentrate platelets containing growth factors to provide support in tissue repair.",[18],"Procedure: Intra articular PRP",{"label":20,"type":10,"description":21,"interventionNames":22},"Intra articular dextrose prolotherapy","Participants will receive dextrose prolotherapy injections, in which a hypertonic dextrose solution that is typically 25% will be injected into the knee joint in order to stimulate joint tissue regeneration.",[23],"Other: Intra articular dextrose prolotherapy",[25,29,31],{"type":26,"name":9,"description":11,"armGroupLabels":27,"otherNames":28},"PROCEDURE",[9],null,{"type":26,"name":15,"description":16,"armGroupLabels":30,"otherNames":28},[15],{"type":6,"name":20,"description":21,"armGroupLabels":32,"otherNames":28},[20],[34],{"name":35,"affiliation":36,"role":37},"Shahid Sarwar","Lincolin university college Malaysia","PRINCIPAL_INVESTIGATOR",[39,44],{"name":40,"role":41,"phone":42,"phoneExt":28,"email":43},"Shahid Sarwar, PhD Scholar","CONTACT","00923002647738","shahidsarwar.phdscholar@lincoln.edu.my",{"name":45,"role":41,"phone":46,"phoneExt":28,"email":47},"Sana Atta, MS","00923095402052","sanaatta33@gmail.com",[49],{"facility":50,"status":28,"city":51,"state":52,"zip":53,"country":54,"countryCode":55,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"Health Sciences","Lahore","Punjab Province","64200","Pakistan","PK",{"type":57,"coordinates":58},"Point",[59,60],74.35071,31.558,{"lat":60,"lon":59},[63,65,66],{"name":40,"role":41,"phone":42,"phoneExt":28,"email":64},"Shahid_sarwar99@yahoo.comshahidsarwar.phdscholar@lincoln.edu.my",{"name":45,"role":41,"phone":46,"phoneExt":28,"email":47},{"name":40,"role":37,"phone":28,"phoneExt":28,"email":28},{"type":37,"investigatorFullName":68,"investigatorTitle":69,"investigatorAffiliation":5,"oldNameTitle":28,"oldOrganization":28},"Shahid sarwar","PhD Scholar","100611654","effects-of-steroid-dextrose-prolotherapy-and-platelet-rich-plasma-injections-in-knee-joint-oa-patients-100611654",false,"NCT07243392","Effects of Steroid, Dextrose Prolotherapy, and Platelet-Rich Plasma Injections in Knee Joint OA Patients","A Comparative Study on Effects of Steroid, Dextrose Prolotherapy, and Platelet-Rich Plasma Injections to Lessen Pain in Knee Osteoarthritis Patients","Inclusion Criteria:Inclusion criteria include patients aged 40-80 years, diagnosed with knee OA having Kellgren- Lawrence grades 2-4(Gelber, 2024) having history of persistent knee pain from at least last six months -\n\nPatients Exclusion reporting with history of recent knee surgery, patients suffering from inflammatory joint diseases for example rheumatoid arthritis, having any active body infection, diabetic patients with de ranged HbA1c, pregnant and breast-feeding females will be excluded.:\n\n\\-","ALL","40 Years","80 Years",{"count":81,"type":82},72,"ESTIMATED","INTERVENTIONAL",[85],"NA","The novelty of thisstudy lies in its comparative assessment of three latest intra-articular injection therapies including steroid injections, dextrose prolotherapy, and PRP, for knee OA associated impairments, with a focus on long-term efficacy and safety profile. While prior studies may have assessed one or two of these treatments individually therefore this protocol is systematically designed.",[88],"Knee Osteoarthritis",[90,91,92,93,94,95,96,97],"Osteoarthristis","Osteoarthritis, Knee","pain","steroids","Platelet-Rich Plasma","Injections, Intra-Articular","Regenerative Medicine.","Prolotherapy","NOT_YET_RECRUITING","2025-11-17",{"date":101,"type":102},"2025-11-21","ACTUAL",{"date":104,"type":82},"2025-11-28",{"date":106,"type":82},"2026-09-01",{"name":5,"class":6},1]