[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100598223":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":27,"centralContacts":31,"locations":41,"responsibleParty":54,"collaborators":18,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":64,"eligibilityCriteria":65,"healthyVolunteers":66,"sex":67,"minAge":68,"maxAge":69,"enrollmentInfo":70,"targetDuration":18,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":82,"overallStatus":88,"whyStopped":18,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"Sinop University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Chiropractic Manipulation Group (CMG)","EXPERIMENTAL","Participants in this group will receive chiropractic manipulation specifically applied to the thumb. The intervention will be administered twice a week for 4 weeks by a trained physiotherapist experienced in manual therapy techniques. Each session will involve standardized manipulation techniques aimed at improving thumb mobility, hand grip strength, sensory function, and overall hand function. No additional interventions or therapies will be provided during the study period.",[13],"Other: Thumb Manipulation",{"label":15,"type":16,"description":17,"interventionNames":18},"Control Group (CG)","NO_INTERVENTION","Participants in the control group will not receive any intervention or treatment during the 4-week study period. They will continue their usual daily activities without any specific therapy applied. Outcome measurements will be conducted at the same time points as the intervention group to allow for comparison.",null,[20],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"Thumb Manipulation","This intervention consists of chiropractic manipulation techniques applied specifically to the thumb joint. The manipulation will be performed by a trained physiotherapist twice weekly for 4 weeks. The procedure aims to improve thumb joint mobility, hand grip strength, sensory function, and overall hand function. Each session includes standardized manual therapy maneuvers targeting the thumb's range of motion and soft tissue mobility without the use of any devices or medications. The intervention differs from other manual therapies by focusing solely on the thumb region.",[9],[25,26],"Chiropractic Thumb Manipulation","Manual Thumb Mobilization",[28],{"name":29,"affiliation":5,"role":30},"SEFA H HATIK","PRINCIPAL_INVESTIGATOR",[32,37],{"name":33,"role":34,"phone":35,"phoneExt":18,"email":36},"SEFA H HATIK, Asst. Prof.","CONTACT","+905058761553","haktanhtk@gmail.com",{"name":38,"role":34,"phone":39,"phoneExt":18,"email":40},"OMER D KIZIL, PhD.","+905415233691","omerdiclekizil@gmail.com",[42],{"facility":5,"status":18,"city":43,"state":18,"zip":18,"country":44,"countryCode":18,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Sinop","Turkey (Türkiye)",{"type":46,"coordinates":47},"Point",[48,49],35.16253,42.02683,{"lat":49,"lon":48},[52,53],{"name":33,"role":34,"phone":35,"phoneExt":18,"email":36},{"name":33,"role":30,"phone":18,"phoneExt":18,"email":18},{"type":55,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"SPONSOR_INVESTIGATOR","SEFA HAKTAN HATIK","Asst. Professor","100598223","effects-of-thumb-manipulation-on-hand-grip-strength-function-and-sensation-100598223",false,"NCT07068698","Effects of Thumb Manipulation on Hand Grip Strength, Function, and Sensation","The Effects of Thumb Manipulation on Hand Grip Strength, Hand Function, and Sensory Parameters","THUMBFUN","Inclusion Criteria:\n\n* Aged between 18 and 50\n* Willing to participate in the study\n* Have signed the informed consent form\n* Able to use verbal and written communication skills\n\nExclusion Criteria:\n\n* Having contraindications that may prevent manipulation\n* Having a history of congenital or acquired orthopedic or neurological conditions affecting the upper extremity\n* Having a history of rheumatological diseases\n* Having a history of trauma or surgery affecting the upper extremity",true,"ALL","18 Years","50 Years",{"count":71,"type":72},60,"ESTIMATED","INTERVENTIONAL",[75],"NA","This randomized controlled study will aim to investigate the effects of thumb manipulation on hand grip strength, function, and sensation in healthy individuals. A total of 60 volunteers aged between 18 and 50 years will be recruited from Ortadağ Special Education and Rehabilitation Center. Participants will be randomly assigned to either a chiropractic manipulation group (n=30) or a control group (n=30), with an equal distribution of males and females in each group. The intervention group will receive thumb manipulation twice weekly for 4 weeks, while the control group will not receive any intervention. Outcome measures will include two-point discrimination (assessed with a discriminator), hand grip strength (measured using a dynamometer), pinch strength (evaluated with a pinch meter), and hand function (measured by the Duruöz Hand Index). Statistical analyses will be performed with a significance level set at p\\\u003C0.05. It is expected that participants in the manipulation group will show greater improvements in all measured parameters compared to the control group, suggesting a positive effect of thumb manipulation on hand-related sensorimotor functions in healthy individuals.",[21,78,79,80,81],"Hand Grip Strength","Hand Sensory Function","Hand Function in Healthy Individuals","Sensory Function",[83,84,85,86,87],"Thumb manipulation","Chiropractic","Hand grip strength","Hand function","Healthy individuals","NOT_YET_RECRUITING","2025-07-07",{"date":91,"type":92},"2025-07-16","ACTUAL",{"date":94,"type":72},"2025-07-06",{"date":96,"type":72},"2025-09-06",{"name":56,"class":6},1]