[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100578585":3},{"organization":4,"armGroups":7,"interventions":28,"overallOfficials":41,"centralContacts":42,"locations":48,"responsibleParty":61,"collaborators":63,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":72,"eligibilityCriteria":73,"healthyVolunteers":68,"sex":74,"minAge":75,"maxAge":76,"enrollmentInfo":77,"targetDuration":41,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":87,"overallStatus":91,"whyStopped":41,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"Egas Moniz - Cooperativa de Ensino Superior, CRL","OTHER",[8,14,19,24],{"label":9,"type":10,"description":11,"interventionNames":12},"tDCS True Modulation","EXPERIMENTAL","Participants will be delivered true treatment for 20 minutes each session",[13],"Device: tDCS",{"label":15,"type":16,"description":17,"interventionNames":18},"tDCS Sham group","SHAM_COMPARATOR","Sham group will be delivers a simulated treatment; the current will be applied for only 60 seconds, with the setup remaining in place for 20 minutes.",[13],{"label":20,"type":10,"description":21,"interventionNames":22},"tVNS True","For true tVNS stimulation, the technique will be performed with the electrodes positioned on the upper concha of the left ear, using gel for better current distribution.",[23],"Device: tVNS",{"label":25,"type":16,"description":26,"interventionNames":27},"tVNS Sham","For sham tVNS stimulation, the technique will be performed in the same way as true stimulation; however, the device will be programmed to deliver 0 Hz.",[23],[29,36],{"type":30,"name":31,"description":32,"armGroupLabels":33,"otherNames":34},"DEVICE","tDCS","For true tDCS, the technique will be performed with the anode over the right dorsolateral prefrontal cortex and the cathode over the left dorsolateral prefrontal cortex, positioned at F4 and F3, respectively, according to the International 10\u002F20 Electrode Placement System. The current intensity will be set to 2 milliamperes (mA) for 20 minutes over five consecutive days.",[15,9],[35],"transcranial Direct Current Stimulation",{"type":30,"name":37,"description":21,"armGroupLabels":38,"otherNames":39},"tVNS",[25,20],[40],"transcutaneous Vagus Nerve Stimulation",null,[43],{"name":44,"role":45,"phone":46,"phoneExt":41,"email":47},"Luciano Maia Alves Ferreira, PhD","CONTACT","+351913548646","lucianomaia@egasmoniz.edu.pt",[49],{"facility":50,"status":41,"city":51,"state":52,"zip":41,"country":53,"countryCode":54,"cosmosGeoPoint":55,"geoPoint":60,"contacts":41},"Egas Moniz Scholl Of Health and Science","Almada","Setúbal District","Portugal","PT",{"type":56,"coordinates":57},"Point",[58,59],-9.1569,38.67902,{"lat":59,"lon":58},{"type":62,"investigatorFullName":41,"investigatorTitle":41,"investigatorAffiliation":41,"oldNameTitle":41,"oldOrganization":41},"SPONSOR",[64],{"name":65,"class":6},"Universidade Federal de Alfenas","100578585","effects-of-transcranial-electrical-stimulation-in-chronic-stress-100578585",false,"NCT06813209","Effects of Transcranial Electrical Stimulation in Chronic Stress","Effects of Transcranial Electrical Stimulation by Continuous Current on the Right and Left Dorsolateral Prefrontal Cortex Associated or Not With Non-invasive Vagus Nerve Stimulation in Adult Individuals With Chronic Stress","NEUROSTIM","Inclusion Criteria:\n\n* individuals previously diagnosed with stress.\n* Obtain a score above 4 on the Lipp Adult Stress Symptom Inventory (ISSL);\n* Must be able to read and understand the purpose of the research and respond to the assessment instruments.\n* Must acknowledge and agree with the informed consent form.\n\nExclusion Criteria:\n\n* smokers;\n* be pregnant;\n* initiation and\u002For change in psychotropic drug dosage in the last three months;\n* use of anxiolytics or antidepressants;\n* substance dependence;\n* history of dizziness or seizures;\n* signs of severity and\u002For indications for hospitalization or psychotherapy;\n* diagnosis of depression; diagnosis of anxiety; bipolar mood disorder with depressive, manic, or hypomanic symptoms in the past year;\n* schizophrenia or other psychotic disorders;\n* autism;\n* diagnosis of epilepsy or use of anticonvulsants;\n* contraindications for tDCS (metal implants, tumor, previous brain surgery, significant cranioencephalic anatomical alterations);\n* contraindications for non-invasive vagus nerve stimulation (cochlear implant, ear plastic surgery, ear malformation);\n* adverse effects detected in the group treated with tDCS and tVNS, including itching, tingling, headache, burning sensation, and discomfort.","ALL","18 Years","50 Years",{"count":78,"type":79},100,"ESTIMATED","INTERVENTIONAL",[82],"NA","This clinical trial aims to determine if Transcranial electrical stimulation by direct current (tDCS) and transauricular Vagus Nerve Stimulation (tVNS) treatments are effective in reducing stress symptoms, distress and improving sleep quality in adults. The main questions it aims to answer are:\n\n* Determine if tDCS effectively reduces the intensity of stress symptoms in adults.\n* Determine if tDCS is effective in reducing levels of distress in adults.\n* Determine if tDCS is effective in improving sleep quality.\n* Determine if tVNS is effective in reducing the intensity of stress symptoms in adults.\n* Determine if tVNS is effective in reducing levels of distress in adults.\n* Determine if tVNS is effective in improving sleep quality.",[85,86],"Stress","Sleep",[88,31,89,90,37],"Transcranial electrical stimulation by direct current","non-invasive vagus nerve stimulation","stress","NOT_YET_RECRUITING","2025-02-03",{"date":94,"type":95},"2025-02-06","ACTUAL",{"date":97,"type":79},"2025-03-01",{"date":99,"type":79},"2027-04",{"name":5,"class":6},1]