[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100634897":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":19,"locations":29,"responsibleParty":45,"collaborators":10,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":10,"eligibilityCriteria":55,"healthyVolunteers":51,"sex":56,"minAge":57,"maxAge":10,"enrollmentInfo":58,"targetDuration":61,"studyType":62,"phases":10,"briefSummary":63,"conditions":64,"keywords":66,"overallStatus":73,"whyStopped":10,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Fatih Sultan Mehmet Training and Research Hospital","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"patient who scalp block applied",null,"Patients who receive an ultrasound-guided preoperative scalp block before skull pin placement and surgical incision",{"label":13,"type":10,"description":14,"interventionNames":10},"patient without scalp block applied","Patients who do not receive a scalp block and instead undergo local infiltration anesthesia performed by the surgical team before skull pin placement and surgical incision",[16],{"name":17,"affiliation":5,"role":18},"arzu yıldırım ar, prof","STUDY_DIRECTOR",[20,25],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"sevgi duymaz","CONTACT","+905050000882","celebisevgi95@gmail.com",{"name":26,"role":22,"phone":27,"phoneExt":10,"email":28},"arzu yıldırım ar","+905053822729","dr.arzuyildirim@hotmail.com",[30],{"facility":5,"status":10,"city":31,"state":32,"zip":33,"country":34,"countryCode":10,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"Istanbul","ataşehir","34752","Turkey (Türkiye)",{"type":36,"coordinates":37},"Point",[38,39],28.94966,41.01384,{"lat":39,"lon":38},[42],{"name":43,"role":22,"phone":44,"phoneExt":10,"email":24},"sevgi duymaz, residant doctor","+9005050000882",{"type":46,"investigatorFullName":47,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Sevgi Duymaz","resident doctor","100634897","effects-of-ultrasound-guided-scalp-block-on-opioid-use-hemodynamics-and-postoperative-inflammation-in-craniotomy-100634897",false,"NCT07545655","Effects of Ultrasound-Guided Scalp Block on Opioid Use, Hemodynamics, and Postoperative Inflammation in Craniotomy","Investigation of the Effects of Preoperative Ultrasound-Guided Scalp Block on Perioperative Opioid Consumption, Hemodynamic Stability, and Inflammatory Response in Patients Undergoing Craniotomy With a Skull Pin Head Holder","Inclusion Criteria:\n\n* Aged 18 years and older\n* Scheduled for elective intracranial surgery with skull pin head holder fixation\n* Classified as American Society of Anesthesiologists (ASA) physical status I-III\n* Provided written informed consent in the preoperative period\n\nExclusion Criteria:\n\n* Allergy to local anesthetics\n* Coagulopathy or anticoagulant use\n* Local infection at injection site\n* Pregnancy or breastfeeding\n* Chronic opioid use (\\>3 months) or chronic pain syndrome\n* Severe psychiatric disorders affecting pain assessment\n* Emergency surgery\n* Active infection or rheumatic disease\n* Hematological disease or malignancy (active or within 5 years)\n* Recent use of biological agents, chemotherapy, or corticosteroids (within 30 days)\n* NSAID use within 24 hours before surgery\n* Advanced organ failure (NYHA III-IV, Child-Pugh C, eGFR \\\u003C30 mL\u002Fmin)\n* Refusal to participate\n* Communication difficulties preventing pain assessment","ALL","18 Years",{"count":59,"type":60},60,"ESTIMATED","1 Year","OBSERVATIONAL","This study shows that in craniotomy patients using a skull pin head holder, an ultrasound-guided scalp block reduces perioperative opioid consumption, improves hemodynamic stability, and decreases the inflammatory response.",[65],"Craniotomy Surgery",[67,68,69,70,71,72],"Craniotomy","Ultrasound-guided scalp block","Skull pin head holder","Perioperative opioid consumption","Hemodynamic stability","Inflammatory response","NOT_YET_RECRUITING","2026-04-21",{"date":76,"type":77},"2026-04-22","ACTUAL",{"date":79,"type":60},"2026-04-10",{"date":81,"type":60},"2027-03-10",{"name":5,"class":6},1]