[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100605957":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":11,"centralContacts":23,"locations":29,"responsibleParty":54,"collaborators":11,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":11,"eligibilityCriteria":63,"healthyVolunteers":59,"sex":64,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":11,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":11,"overallStatus":76,"whyStopped":11,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"Princess Nourah Bint Abdulrahman University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Hijama Group","EXPERIMENTAL",null,[13],"Procedure: Wet-cupping",{"label":15,"type":16,"description":11,"interventionNames":11},"Control Group","NO_INTERVENTION",[18],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":11},"PROCEDURE","Wet-cupping","The intervention consists of three sessions of wet cupping therapy (Hijama), administered once every month over three consecutive months. This study's protocol is distinguished by its standardized, medically supervised approach, designed to align traditional Hijama practices with modern clinical trial standards.\n\nKey features that distinguish this intervention include:\n\nStandardized Procedure: The Hijama protocol follows a detailed, consistent method including suction, superficial skin incisions, and reapplication of suction, followed by honey dressing. All sessions use disposable, single-use instruments and follow strict infection control measures.\n\nTiming Based on Prophetic Recommendation: Cupping is performed on the 17th, 19th, or 21st day of the Islamic lunar month, which is rooted in Islamic tradition and rarely standardized in scientific studies.\n\nCertified Practitioner and Setting: Procedures are conducted by a licensed Hijama practitioner with",[9],[24],{"name":25,"role":26,"phone":27,"phoneExt":11,"email":28},"Nouran Aleyeidi","CONTACT","+966504304577","naaleyeidi@pnu.edu.sa",[30],{"facility":31,"status":11,"city":32,"state":33,"zip":34,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"King Abdullah bin Abdulaziz University Hospital","Riyadh","Central","13249","Saudi Arabia","SA",{"type":38,"coordinates":39},"Point",[40,41],46.72185,24.68773,{"lat":41,"lon":40},[44,46,49,52],{"name":25,"role":26,"phone":45,"phoneExt":11,"email":28},"0504304577",{"name":47,"role":48,"phone":11,"phoneExt":11,"email":11},"Hanan Dahlawi","PRINCIPAL_INVESTIGATOR",{"name":50,"role":51,"phone":11,"phoneExt":11,"email":11},"Hanadi Bakhsh","SUB_INVESTIGATOR",{"name":53,"role":51,"phone":11,"phoneExt":11,"email":11},"Mamoun Elawad",{"type":48,"investigatorFullName":55,"investigatorTitle":56,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"Nouran Abdullah Aleyeidi","Dr.","100605957","effects-of-wet-cupping-on-polycystic-ovary-syndrome-patients-100605957",false,"NCT07169292","Effects of Wet-Cupping on Polycystic Ovary Syndrome Patients","Effects of Wet-Cupping on Polycystic Ovary Syndrome Patients: A Randomized Controlled Trial","Inclusion Criteria\n\n* Female participants.\n* Aged 20 to 40 years.\n* Diagnosed with Polycystic Ovary Syndrome (PCOS) according to the Rotterdam criteria.\n* Willing to participate in the study and provide informed consent.\n* Not using any of the following in the last month: (Hormonal medications for menstruation, Herbal menstrual remedies or Metformin).\n\nExclusion Criteria\n\n* Known diagnosis of uncontrolled thyroid dysfunction.\n* Diagnosis of diabetes mellitus.\n* Elevated FSH levels above 20 mIU\u002FmL.\n* Hyperprolactinemia with serum levels above 1000 mIU\u002FL.\n* Pregnant or lactating women.\n* Known coagulation disorders.\n* Anemia with hemoglobin levels less than 10 g\u002FdL.\n* History of undergoing dry cupping, wet cupping, or acupuncture in the past 6 months.\n* History of surgical removal of both ovaries or the uterus.\n* Other causes of hyperandrogenism, including:\n* Late-onset non-classic 21-hydroxylase deficiency (excluded clinically; lab investigation if clinically indicated).\n* Ovarian androgen-secreting tumors.\n* Use of anabolic or androgenic drugs.\n* Cushing's syndrome.\n* Hypothalamic or pituitary disorders causing amenorrhea.\n* Primary ovarian insufficiency.","FEMALE","20 Years","40 Years",{"count":68,"type":69},60,"ESTIMATED","INTERVENTIONAL",[72],"NA","The goal of this clinical trial is to evaluate whether wet cupping therapy (Hijama) can improve reproductive and metabolic outcomes in women diagnosed with Polycystic Ovary Syndrome (PCOS). This study will be conducted among female participants aged 20-40 years who have been diagnosed with PCOS according to the Rotterdam criteria.\n\nThe main questions it aims to answer are:\n\nCan wet cupping therapy regulate menstrual cycles in women with PCOS?\n\nCan it increase the pregnancy rate in married participants with PCOS-related infertility?\n\nResearchers will compare outcomes between a wet cupping group and a control group to determine whether Hijama has significant effects on reproductive, hormonal, and metabolic markers.\n\nParticipants will:\n\nUndergo screening and eligibility evaluation using a checklist\n\nBe randomized into either the wet cupping (intervention) or control group\n\nReceive lifestyle counseling (diet and physical activity)\n\nFor the intervention group:\n\nReceive one Hijama session performed by a certified practitioner\n\nUndergo follow-up at 4 and 12 weeks for clinical, hormonal, and ultrasound assessments\n\nFor all participants:\n\nComplete laboratory tests, ultrasound scans, and questionnaires on PCOS symptoms and quality of life\n\nReport any side effects during and after the study period",[75],"Polycystic Ovarian Syndrome (PCOS)","NOT_YET_RECRUITING","2025-09-05",{"date":79,"type":80},"2025-09-11","ACTUAL",{"date":82,"type":69},"2026-01-01",{"date":84,"type":69},"2026-12-31",{"name":5,"class":6},1]