[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100596495":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":20,"locations":19,"responsibleParty":26,"collaborators":19,"id":30,"slug":31,"hasResults":32,"nctId":33,"briefTitle":34,"officialTitle":35,"acronym":36,"eligibilityCriteria":37,"healthyVolunteers":32,"sex":38,"minAge":39,"maxAge":40,"enrollmentInfo":41,"targetDuration":19,"studyType":44,"phases":45,"briefSummary":47,"conditions":48,"keywords":19,"overallStatus":53,"whyStopped":19,"lastUpdateSubmitDate":54,"lastUpdatePostDateStruct":55,"startDateStruct":58,"completionDateStruct":60,"leadSponsor":62,"locationsCount":19},{"fullName":5,"class":6},"Universidade do Estado do Pará","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Rehabilitation for long covid","EXPERIMENTAL","Physioterapy protocol",[13],"Other: physiothreapy protocol",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"physiothreapy protocol","Aerobic training (treadmill or exercise bike) for 15 minutes, anaerobic training at the weight training station, performing exercises for the upper limbs (bench press and front pull) and lower limbs (180º leg press and extension chair) with weight determined by the 1 Repetition Maximum (1RM) test, performing 3 sets of 12-15 repetitions (depending on the session) and respiratory muscle training using POWERbreathe (30-40% of the MIP performed in the manovacuometry test).",[9],null,[21],{"name":22,"role":23,"phone":24,"phoneExt":19,"email":25},"Luiz Magno Falcão, Research and coordinator","CONTACT","+5591982379488","fabiofalcao@uepa.br",{"type":27,"investigatorFullName":28,"investigatorTitle":29,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"PRINCIPAL_INVESTIGATOR","Luiz Fábio Magno Falcão, PhD","Researcher","100596495","effects-os-physiotherapeutic-rehabilitation-on-function-autonomic-and-inflammatory-in-patients-with-long-covid-100596495",false,"NCT07046208","Effects os Physiotherapeutic Rehabilitation on Function Autonomic and Inflammatory in Patients With Long Covid","Effects os Physiotherapeutic Rehabilitation on Cardiovascular Autonomic Modulation and Biomarkers Inflammatory and Cardiac Conditions in Patients With Long Covid","LongCovidRehab","Inclusion Criteria:\n\n* both sexes\n* aged 20 and 59 years\n* clinical evaluation and undergoing clinical follow-up of Post COVID-19.\n* least one persistent COVID-19-related symptom.\n\nExclusion Criteria:\n\n* incomplete data.\n* presence of a pacemaker\n* use of antihypertensive drugs that alter HRV\n* persistent pulmonary alterations\n* persistent desaturation\n* anaemia or presence of reinfection.","ALL","20 Years","59 Years",{"count":42,"type":43},58,"ESTIMATED","INTERVENTIONAL",[46],"NA","Introduction: Long COVID is characterized by persistent symptoms that persist for weeks or months after the acute phase of infection, with a significant impact on the cardiovascular and autonomic systems. Objectives: This study aims to evaluate the effects of a physiotherapeutic rehabilitation protocol on cardiovascular autonomic modulation and on inflammatory and cardiac biomarkers in patients with Long COVID. Methodology: This is a controlled clinical trial, carried out in a cardiorespiratory rehabilitation outpatient clinic, involving individuals with a clinical diagnosis of Long COVID undergoing a protocol of 20 aerobic, anaerobic and respiratory rehabilitation sessions. Heart rate variability (HRV) variables will be analyzed using linear and non-linear methods, in addition to serum levels of CKMB, LDH, ferritin and C-reactive protein. Expected results: Rehabilitation is expected to provide an improvement in autonomic function and a reduction in inflammatory and cardiac markers, contributing to the understanding of the pathophysiological mechanisms of Long COVID and helping to propose evidence-based therapeutic strategies.",[49,50,51,52],"Long COVID","Heart Rate Variability (HRV)","Cardiac Biomarkers","Inflammatory Biomarkers","NOT_YET_RECRUITING","2025-06-29",{"date":56,"type":57},"2025-07-01","ACTUAL",{"date":59,"type":43},"2025-08-11",{"date":61,"type":43},"2026-09-30",{"name":5,"class":6}]