[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100623834":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":26,"responsibleParty":37,"collaborators":26,"id":39,"slug":40,"hasResults":41,"nctId":42,"briefTitle":43,"officialTitle":43,"acronym":26,"eligibilityCriteria":44,"healthyVolunteers":41,"sex":45,"minAge":46,"maxAge":47,"enrollmentInfo":48,"targetDuration":26,"studyType":51,"phases":52,"briefSummary":54,"conditions":55,"keywords":59,"overallStatus":62,"whyStopped":26,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":26},{"fullName":5,"class":6},"Second Affiliated Hospital of Nanchang University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"treatment group","EXPERIMENTAL","The full-automatic ischemic preconditioning therapeutic instrument was used to pressurize the patients ' upper arms ( experimental group pressure = 200 mmHg ) for 5 minutes, and then breathe out for 5 minutes, which was an ischemia-reperfusion cycle. Each training was performed for 5 consecutive cycles, once in the morning and once in the afternoon, twice a day, at least 5 days a week, for a total of 4 weeks.",[13],"Device: Automatic ischemic preconditioning therapeutic apparatus",{"label":15,"type":16,"description":17,"interventionNames":18},"control group","SHAM_COMPARATOR","Participants in this group will use a sham training device that is identical in appearance, sound, and sense of wear to the experimental device. The treatment plan was consistent with the experimental group in time and process : wearing a cuff for 5 minutes, rest for 5 minutes, a total of 5 cycles. The key difference is that during the so-called ' pressure ', the cuff is inflated to a pressure of only 60 mmHg to simulate the sense of operation of the device and a slight sense of skin contact. The treatment frequency, cycle and execution personnel were the same as those of the experimental group.",[19],"Device: Sham Ischemic Preconditioning Device",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Automatic ischemic preconditioning therapeutic apparatus","The patient 's upper arms were pressurized for 5 minutes( Test group pressure = 200 mmHg ), and then breathed for 5 minutes. It was an ischemia-reperfusion cycle. Each training was performed for 5 consecutive cycles, 1 in the morning and 1 in the afternoon, 2 times \u002F day, at least 5 days a week, for a total of 4 weeks.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Sham Ischemic Preconditioning Device","A sham training device that is identical in appearance, sound, and wear sensation to the experimental device. During the \"pressure\" phase, the cuff is inflated to a non-ischemic low pressure (60 mmHg) to mimic device operation. The treatment schedule (cycles, frequency, duration) is identical to the experimental arm.",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Liang Xie","CONTACT","+86 18679162717","Ndefy14067@ncu.edu.cn",{"type":38,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100623834","efficacy-and-safety-evaluation-of-remote-ischemic-adaptation--intermittent-pressure-stimulation--in-the-treatment-of-insomnia-after-stroke-100623834",false,"NCT07401784","Efficacy and Safety Evaluation of Remote Ischemic Adaptation ( Intermittent Pressure Stimulation ) in the Treatment of Insomnia After Stroke","Inclusion Criteria:\n\n* Age 18-80 years old ;\n* In line with the diagnostic criteria of ischemic stroke, with reference to the ' Chinese guidelines for the diagnosis and treatment of acute ischemic stroke ' diagnosed ischemic stroke ;\n* Despite adequate sleep opportunities, patients still have difficulty in falling asleep or maintaining sleep, staying asleep at least 3 times a week for at least 3 months, which leads to pain or impaired daytime function.\n* PSQI score ≥ 6 and ISI score ≥ 8 ;\n* All research contents have been understood and informed consent has been signed.\n\nExclusion Criteria:\n\n* Insomnia before stroke ;\n* Patients with mental disorders, bipolar disorder or depression, generalized anxiety disorder and other mental disorders ;\n* Patients were pregnant or lactating women ;\n* Other reasons identified by the researchers are not suitable for patients ;","ALL","18 Years","80 Years",{"count":49,"type":50},40,"ESTIMATED","INTERVENTIONAL",[53],"NA","The incidence of post-stroke depression is high, which will affect the rehabilitation of neurological function, damage cognitive function, and increase the risk of subsequent stroke recurrence. The guidelines recommend that in addition to antiplatelet, blood pressure control, lipid-lowering and other treatments, secondary prevention of post-stroke depression should also be strengthened. Moreover, after the occurrence of post-stroke depression, methods such as medication and psychotherapy have their own limitations, such as potential adverse drug reactions and limited psychotherapy. Therefore, it is necessary to pay attention to the prevention of post-stroke depression.\n\nThe remote ischemic adaptation therapy applied in our study is a safe, non-invasive and convenient physical therapy. By transiently and repeatedly applying ischemia-reperfusion stimulation to both upper arms, it induces a systemic protective response, improves the brain 's tolerance to ischemia and hypoxia, and exerts a protective effect on multiple organs such as the brain and heart. The RIC therapeutic instrument has been national patented and has been maturely applied to the prevention and treatment of acute cerebral infarction, which can promote the rehabilitation of neurological function. In addition, it also has certain curative effect in the treatment of cerebrovascular stenosis, refractory hypertension, depression, insomnia, anxiety and so on.",[56,57,58],"Cerebral Apoplexy","Depression Anxiety Disorder","Cerebrovascular Disease",[60,61,57,58],"Remote ischemic adaptation technology","cerebral apoplexy","NOT_YET_RECRUITING","2026-02-03",{"date":65,"type":66},"2026-02-10","ACTUAL",{"date":68,"type":50},"2026-01-27",{"date":70,"type":50},"2027-12-30",{"name":5,"class":6}]