[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100579204":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":32,"centralContacts":33,"locations":39,"responsibleParty":56,"collaborators":32,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":66,"eligibilityCriteria":67,"healthyVolunteers":62,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":32,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":80,"overallStatus":42,"whyStopped":32,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"University of Salerno","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Real tDCS group","EXPERIMENTAL","Partecipants receive anodal tDCS over the cerebellum area (2 cm under the inion, using a 7 × 5 cm sponge electrode), with the cathode being applied either to the right deltoid muscle (arm 1: cerebellar stimulation) or over the spinal lumbar enlargement (2 cm under T11; arm 2: cerebellar-spinal stimulation) using a sponge electrode of the same size as the anode for 5 days\u002Fweek for 2 weeks",[13],"Device: Anodal transcranial direct current stimulation (a-tDCS)",{"label":15,"type":16,"description":17,"interventionNames":18},"Sham group","SHAM_COMPARATOR","Partecipants receive sham stimulation over the cerebellum area (2 cm under the inion, using a 7 × 5 cm sponge electrode), with the cathode being applied either to the right deltoid muscle (arm 1: cerebellar stimulation) or over the spinal lumbar enlargement (2 cm under T11; arm 2: cerebellar-spinal stimulation) using a sponge electrode of the same size as the anode for 5 days\u002Fweek for 2 weeks",[19],"Device: Sham stimulation",[21,28],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Anodal transcranial direct current stimulation (a-tDCS)","tDCS is delivered by a battery-driven constant current stimulator throught a pair of saline soaked surface sponge electrodes. The active electrode (anode) is placed on the scalp over the over the cerebellum area (2 cm under the inion, using a 7 × 5 cm sponge electrode), with the cathode being applied either to the right deltoid muscle (arm 1: cerebellar stimulation) or over the spinal lumbar enlargement (2 cm under T11; arm 2: cerebellar-spinal stimulation) using a sponge electrode of the same size as the anode. Durng real stilumation a costant current of 2mA is applied for 20 minutes.",[9],[27],"Active stimulation",{"type":22,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"Sham stimulation","For the sham condition the electrode placement is the same of active tDCS but the electric current is ramped down 5 seconds after the beginning of the stimulation",[15],null,[34],{"name":35,"role":36,"phone":37,"phoneExt":32,"email":38},"Roberto Erro MD, PhD","CONTACT","089673073","rerro@unisa.it",[40],{"facility":41,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Centro per le Malattie Neurodegenerative (CEMAND) Dipartimento di Medicina e chirurgia, Sezione Neuroscienze, Università di Salerno","RECRUITING","Salerno","Sa","84131","Italy","IT",{"type":49,"coordinates":50},"Point",[51,52],14.79328,40.67545,{"lat":52,"lon":51},[55],{"name":35,"role":36,"phone":37,"phoneExt":32,"email":38},{"type":57,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":32,"oldOrganization":32},"PRINCIPAL_INVESTIGATOR","Roberto Erro","Principal Investigator","100579204","efficacy-and-safety-of-transcranial-direct-current-stimulation-in-multiple-system-atrophy-cerebellar-variant-100579204",false,"NCT06821256","Efficacy and Safety of Transcranial dIrect Current stiMulation in Multiple System Atrophy-Cerebellar Variant","Efficacy and Safety of Transcranial dIrect Current stiMulation (tDCS) on Cerebellar Symptoms in Multiple System Atrophy-Cerebellar Variant (MSA-C) (STIM-MSA)","STIM-MSA","Inclusion Criteria:\n\n* Multiple system atrophy cerebellar variant according with the Movemente Disorder Society criteria (Wenning et al 2022)\n* Ability to walk either indipendently or with a minimum support\n\nExclusion Criteria:\n\n* Presence of electrical stimulators (for example, pacemaker, Deep Brain Stimulation, DBS)\n* Difficult in understanding Italian language\n* Presence of severe sensory deficits (for example, visual or hearing impairments)\n* History of drug abuse\n* History of severe psychiatric disorders\n* History of transient ischemic attacks\n* Cortical or sub-cortical vascular lesions\n* Seizures or severe heart problems and previous neurosurgical operations\n* Pregnancy","ALL","40 Years","90 Years",{"count":72,"type":73},30,"ESTIMATED","INTERVENTIONAL",[76],"NA","This is a double-blind, randomized, sham-controlled clinical trial that aim to verify the safety and the efficacy of anodal transcranial direct current stimulation (tDCS) cerebellar symptoms in Multiple System Atrophy type C (MSA).",[79],"Multiple System Atrophy - Cerebellar Subtype (MSA-C)",[81,82],"Multiple System Atrophy type C (MSA-C),","Transcranial direct current stimulation (tDCS)","2026-04-28",{"date":85,"type":86},"2026-04-29","ACTUAL",{"date":88,"type":86},"2023-07-03",{"date":90,"type":73},"2027-12",{"name":5,"class":6},1]