[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100635065":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":19,"locations":19,"responsibleParty":20,"collaborators":19,"id":24,"slug":25,"hasResults":26,"nctId":27,"briefTitle":28,"officialTitle":29,"acronym":19,"eligibilityCriteria":30,"healthyVolunteers":31,"sex":32,"minAge":33,"maxAge":34,"enrollmentInfo":35,"targetDuration":19,"studyType":38,"phases":39,"briefSummary":41,"conditions":42,"keywords":45,"overallStatus":49,"whyStopped":19,"lastUpdateSubmitDate":50,"lastUpdatePostDateStruct":51,"startDateStruct":54,"completionDateStruct":56,"leadSponsor":58,"locationsCount":19},{"fullName":5,"class":6},"Assiut University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Autologous Fat Grafting","EXPERIMENTAL","Participants in this arm will undergo penile girth enhancement via autologous fat grafting. Approximately 40-80 mL of fat will be harvested from the patient's lower abdomen using a multiperforated cannula. The fat is then purified with physiological saline and mechanically refined to reduce globule size. Finally, the prepared fat is injected into the penile subdartos space across four quadrants using a blunt 18-gauge cannula to ensure uniform distribution.",[13],"Procedure: Autologous Fat Grafting",[15],{"type":16,"name":9,"description":17,"armGroupLabels":18,"otherNames":19},"PROCEDURE","Approximately 40-80 mL of body fat is harvested from the patient's lower abdomen using a multiperforated cannula. The harvested fat is repeatedly washed with sterile physiological saline to remove blood and debris, then undergoes mechanical refinement to reduce globule size. Finally, the refined fat is transferred to 3-mL syringes and injected into the four quadrants of the penile dartos layer (just above the tunica albuginea) using a blunt 18-gauge cannula.",[9],null,{"type":21,"investigatorFullName":22,"investigatorTitle":23,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"PRINCIPAL_INVESTIGATOR","Mohamed Assem Hussein","Resident at Andrology Department, Assiut University","100635065","efficacy-and-stability-of-autologous-fat-grafting-for-penile-girth-augmentation-100635065",false,"NCT07547839","Efficacy and Stability of Autologous Fat Grafting for Penile Girth Augmentation","Efficacy and Stability of Autologous Fat Grafting for Penile Girth Augmentation: Clinical and Radiologic Follow-up","Inclusion Criteria:\n\n* Male individuals dissatisfied with their penile girth\n* Mid-shaft penile circumference at flaccid state less than 11 cm\n* Regular coital activity\n* Age between 21-60 years old\n\nExclusion Criteria:\n\n* Mid-shaft penile circumference at flaccid state more than 11 cm\n* Congenital penile deformities\n* Previous penile augmentation\n* Inflammatory skin infection (balanitis)\n* Blood disorder such as hemophilia, leukemia, or lymphoma\n* Psychiatric disorder such as body dysmorphic disorder, bipolar disorder, obsessive compulsive disorder (OCD), or depression",true,"MALE","21 Years","60 Years",{"count":36,"type":37},25,"ESTIMATED","INTERVENTIONAL",[40],"NA","The primary aim of this study is to evaluate the clinical and radiological efficacy and long-term stability of autologous fat grafting as a method for girth augmentation. The procedure involves extracting approximately 40-80 mL of fat from the patient's lower abdomen. This harvested fat is repeatedly washed , and then injected into the penile dartos layer to enhance penile circumference.\n\nThe study will enroll male individuals between 21-60 years old who have regular coital activity, are dissatisfied with their penile girth, and have a flaccid mid-shaft penile circumference of less than 11 cm.\n\nResearchers will measure the clinical success of the procedure by tracking the mean change in penile mid-shaft circumference. Additionally, high-resolution ultrasonography will be used at 6 weeks post-operatively to objectively assess the survival and thickness of the transplanted fat layer. Finally, at a three-month follow-up, patient satisfaction will be evaluated to measure improvements in aesthetic outcomes and functional satisfaction.",[43,44],"Penile Girth Augmentation","Fat Graft",[43,9,46,47,48],"Fat Transfer","Penile Enhancement","Ultrasonography","NOT_YET_RECRUITING","2026-04-17",{"date":52,"type":53},"2026-04-23","ACTUAL",{"date":55,"type":37},"2026-05",{"date":57,"type":37},"2027-06",{"name":5,"class":6}]