[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100612922":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":25,"locations":25,"responsibleParty":31,"collaborators":35,"id":44,"slug":45,"hasResults":46,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":46,"sex":52,"minAge":53,"maxAge":54,"enrollmentInfo":55,"targetDuration":25,"studyType":58,"phases":59,"briefSummary":61,"conditions":62,"keywords":25,"overallStatus":64,"whyStopped":25,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":25},{"fullName":5,"class":6},"University of Pisa","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Left hemisphere lesion group","EXPERIMENTAL","The stroke patients with left hemisphere lesion will be performing the bilateral robotic treatment with the exoskeleton ALEx-RS followed by a standard manual treatment",[13,14],"Device: Bilateral robotic treatment for the upper limbs","Behavioral: Standard physiotherapy",{"label":16,"type":10,"description":17,"interventionNames":18},"Right hemisphere lesion group","The stroke patients with right hemisphere lesion will be performing the bilateral robotic treatment with the exoskeleton ALEx-RS followed by a standard manual treatment",[13,14],[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","Bilateral robotic treatment for the upper limbs","Patients will perform a specific sequence of exercises with the exoskeleton for the upper limbs ALEx-RS, including passive and active-assisted movements, unilateral and bilateral reaching tasks with visual feedback, and symmetric and asymmetric bimanual coordination tasks.",[9,16],null,{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":25},"BEHAVIORAL","Standard physiotherapy","After the robotic treatment, patients will undergo 20 minutes of conventional treatment consisting of passive and active-assisted mobilization with the help of a physiotherapist.",[9,16],{"type":32,"investigatorFullName":33,"investigatorTitle":34,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Carmelo Chisari","Professor",[36,38,40,42],{"name":37,"class":6},"Azienda Ospedaliero, Universitaria Pisana",{"name":39,"class":6},"Villa Beretta Rehabilitation Center",{"name":41,"class":6},"Fondazione Don Carlo Gnocchi Onlus",{"name":43,"class":6},"Ospedale Policlinico San Martino","100612922","efficacy-of-a-bilateral-robotic-treatment-in-chronic-patients-100612922",false,"NCT07259876","Efficacy of a Bilateral Robotic Treatment in Chronic Patients","Efficacy and Neurophysiological Correlates of a Bilateral Robotic Treatment for the Upper Limbs in Patients With Chronic Stroke Outcomes","BUILT","Inclusion Criteria:\n\n* Subjects aged between 18 and 80 years, of either sex\n* Subjects able to understand and provide, or have provided on their behalf, informed consent\n* History of a single unilateral ischemic or hemorrhagic cerebrovascular event in the chronic phase (\\> 6 months)\n* Subjects with mild to moderate functional impairment of the right or left upper limb (ability to perform antigravity active movements)\n\nExclusion Criteria:\n\n* Subjects with cognitive deficits that impair understanding of the required tasks (MMSE score corrected for age and education \\\u003C 24\u002F30)\n* Subjects with severe visual deficits\n* Subjects with upper limb spasticity preventing the use of robotic devices (spasticity measured using the Modified Ashworth Scale \\> 3)\n* Inability or unwillingness to provide informed consent\n* Left-handed subjects","ALL","18 Years","80 Years",{"count":56,"type":57},60,"ESTIMATED","INTERVENTIONAL",[60],"NA","The goal of this clinical trial is to evaluate how manual dominance influences the effectiveness of bilateral robotic treatment in right-handed patients with chronic stroke.\n\nResearchers will compare the outcome of a bilateral robotic treatment for the upper limbs in left vs right hemisphere lesions following stroke.\n\nParticipants will:\n\n* perform a bilateral robotic treatment for the upper limb (15 sessions in three weeks) followed by 20-minutes standard manual rehabilitative sessions\n* be evaluated before and after treatment with clinical scales, resting- state EEG and kinematic measurements",[63],"Stroke","NOT_YET_RECRUITING","2026-04-27",{"date":67,"type":68},"2026-04-28","ACTUAL",{"date":70,"type":57},"2026-07",{"date":72,"type":57},"2026-12",{"name":5,"class":6}]