[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100596874":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":11,"centralContacts":34,"locations":11,"responsibleParty":40,"collaborators":11,"id":42,"slug":43,"hasResults":44,"nctId":45,"briefTitle":46,"officialTitle":46,"acronym":11,"eligibilityCriteria":47,"healthyVolunteers":44,"sex":48,"minAge":49,"maxAge":50,"enrollmentInfo":51,"targetDuration":11,"studyType":54,"phases":55,"briefSummary":57,"conditions":58,"keywords":62,"overallStatus":73,"whyStopped":11,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":11},{"fullName":5,"class":6},"Universitat Jaume I","OTHER",[8,14,17,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Early responders selfapplied completed","EXPERIMENTAL",null,[13],"Behavioral: UJI Online Transdiagnostic Protocol",{"label":15,"type":10,"description":11,"interventionNames":16},"Early responders selfapplied interrupted",[13],{"label":18,"type":10,"description":11,"interventionNames":19},"Late responders selfapplied",[13],{"label":21,"type":10,"description":11,"interventionNames":22},"Late responders blended",[23],"Behavioral: UJI On Line Transdiagnostic Hibrid Protocol",[25,30],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":11},"BEHAVIORAL","UJI Online Transdiagnostic Protocol","Is a manualized treatment for emotional disorders delivered through an interactive multimedia platform. The self applied format consists of 12 self applied modules (psychoeducation, emotional processing, cognitive flexibility training, exposure, coping strategies, maladaptive behaviors, avoidance, etc)",[9,15,18],{"type":26,"name":31,"description":32,"armGroupLabels":33,"otherNames":11},"UJI On Line Transdiagnostic Hibrid Protocol","Hybrid format: 12 self applied modules with two synchronous videoconference sessions with a trained therapist",[21],[35],{"name":36,"role":37,"phone":38,"phoneExt":11,"email":39},"Fernanda Longo Elia, Psychologist","CONTACT","+541159643668","FERLONGO1@GMAIL.COM",{"type":41,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100596874","efficacy-of-a-personalized-response-based-transdiagnostic-intervention-for-emotional-disorders-delivered-via-the-internet-a-protocol-for-an-adaptive-randomized-controlled-trial-100596874",false,"NCT07051148","Efficacy of a Personalized, Response-based Transdiagnostic Intervention for Emotional Disorders Delivered Via the Internet: A Protocol for an Adaptive Randomized Controlled Trial","Inclusion Criteria:\n\n* Spanish speakers\n* OASIS score +\u002F= 8\n* ODSIS score +\u002F= 7\n* Access to Internet\n* Email\n\nExclusion Criteria:\n\n* Severe mental disorder: schizophrenia\u002Fbipolar disorder\n* Active substance abuse\n* High suicide risk\n* Ongoing psychological\u002Fpharmacological treatment\n* Interfering physical illness","ALL","18 Years","70 Years",{"count":52,"type":53},366,"ESTIMATED","INTERVENTIONAL",[56],"NA","This adaptive randomized controlled trial evaluates the efficacy of a transdiagnostic, internet-delivered psychological intervention for emotional disorders, tailored to patient´s early clinical response. 366 adults with clinically significant symptoms of depression and\u002For anxiety will begin a 12 module self-applied program. Based on sympton reduction after the first three modules, participants will be classified as early or late responders and randomized into different experimental arms. The main hypothesis is that a hybrid format (self-applied modules plus synchronous sessions with a therapist) will yield better outcomes for late responders. Outcomes include symptom reduction, emotional regulation and internet based therapheutic alliance.",[59,60,61],"Emotional Disorders","Anxiety","Depression, Unipolar",[63,64,65,66,59,67,68,69,70,71,72],"transdiagnostic","internet based therapy","anxiety","depression","adaptive intervention","blended treatment","digital interventions","personalization","personalized treatment","adaptive trial","NOT_YET_RECRUITING","2026-05-21",{"date":76,"type":77},"2026-05-27","ACTUAL",{"date":79,"type":53},"2027-05-01",{"date":81,"type":53},"2030-07",{"name":5,"class":6}]