[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100638340":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":50,"collaborators":26,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":26,"eligibilityCriteria":60,"healthyVolunteers":61,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":26,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":74,"overallStatus":80,"whyStopped":26,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"Ain Shams University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Theravex - Xenograft mixture group","EXPERIMENTAL","Patients in this group will undergo internal maxillary sinus lift via the osseodensification technique with simultaneous dental implant placement, utilizing a mixture of Theravex (Bone Bioactive Liquid) and xenograft and as the grafting material.",[13],"Biological: Internal Sinus lifting using Theravex-Xenpgraft mixture",{"label":15,"type":16,"description":17,"interventionNames":18},"Xenograft alone group","ACTIVE_COMPARATOR","Patients in this group will undergo internal maxillary sinus lift via the osseodensification technique with simultaneous dental implant placement, utilizing xenograft alone as the grafting material.",[19],"Biological: Internal Sinus lifting using Xenpgraft alone",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BIOLOGICAL","Internal Sinus lifting using Theravex-Xenpgraft mixture","Application of a grafting mixture consisting of an equine granulate xenograft hydrated with Theravex (Bone Bioactive Liquid) into the osteotomy site.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Internal Sinus lifting using Xenpgraft alone","Application of an equine granulate xenograft alone into the osteotomy site.",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Eslam Osama Hashem, Master's","CONTACT","+201100673726","eslamhashim@dent.asu.edu.eg",[38],{"facility":39,"status":26,"city":40,"state":26,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":26},"Faculty of Dentistry Ain Shams university","Cairo","11566","Egypt","EG",{"type":45,"coordinates":46},"Point",[47,48],31.24967,30.06263,{"lat":48,"lon":47},{"type":51,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Eslam Hashem","Resident","100638340","efficacy-of-adjunctive-theravex-tissue-care-with-xenograft-in-internal-sinus-lifting-100638340",false,"NCT07627633","Efficacy of Adjunctive Theravex Tissue Care® With Xenograft in Internal Sinus Lifting","Efficacy of Adjunctive Theravex Tissue Care® With Xenograft Using Osseodensification in Internal Sinus Lifting: a Randomized Controlled Clinical Study","Inclusion Criteria:\n\n* Patient partially edentulous with maxillary posterior edentulous ridge after extraction of more than 4 months.\n* Both genders will be selected males and females.\n* Adult patients aged between 21 and 50 years of age.\n* Good general health (American Society of Anesthesiology Physical Status I-II).\n* Initial residual alveolar ridge height ranging between 4 to 6 mm according to preoperative CBCT.\n* No previous surgery or radiation treatment on the maxillary sinus\n\nExclusion Criteria:\n\n* Smokers\n* Pregnant and lactating females.\n* Poor oral hygiene (Full-Mouth Plaque Score (FMPS) \\> 20%).\n* Patients with occlusal or malalignment problems.\n* Patients with parafunctional habits.\n* Presence of acute or chronic sinus pathoses or sinus membrane perforation.",true,"ALL","21 Years","50 Years",{"count":66,"type":67},16,"ESTIMATED","INTERVENTIONAL",[70],"NA","The purpose of this clinical study is to evaluate the clinical and radiographic efficacy of Theravex Tissue Care Plus (Bone Bioactive Liquid) as an adjunct to a xenograft in crestal maxillary sinus elevation with simultaneous implant placement using the osseodensification technique. The study will enroll 16 partially edentulous patients who have inadequate posterior maxillary bone height. Participants will randomly undergo the sinus elevation and implant placement utilizing either a xenograft alone or a mixture of the xenograft and Theravex. The main question the study aims to answer is whether the adjunctive use of Theravex with a xenograft enhances vertical bone gain, bone density, and implant stability compared to using a xenograft alone.",[73],"Internal Sinus Lifting",[75,76,73,77,78,79],"Bone Bioactive Liquid","Theravex Tissue Care","Implant","Xenograft","Sinus augmentation","NOT_YET_RECRUITING","2026-05-30",{"date":83,"type":84},"2026-06-04","ACTUAL",{"date":86,"type":67},"2026-10-01",{"date":88,"type":67},"2029-05-01",{"name":5,"class":6},1]