[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100607700":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":11,"centralContacts":34,"locations":40,"responsibleParty":53,"collaborators":11,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":11,"eligibilityCriteria":61,"healthyVolunteers":57,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":11,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":74,"overallStatus":77,"whyStopped":11,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Taipei Medical University WanFang Hospital","OTHER",[8,16],{"label":9,"type":10,"description":11,"interventionNames":12},"SSSI (active) + iACB and PC-LIA","ACTIVE_COMPARATOR",null,[13,14,15],"Procedure: Supra-Sartorial Subcutaneous Infiltration (SSSI)","Procedure: intermittent adductor canal block (iACB)","Procedure: posterior capsule local infiltration analgesia (PC-LIA)",{"label":17,"type":18,"description":11,"interventionNames":19},"SSSI (sham) + iACB and PC-LIA","PLACEBO_COMPARATOR",[13,14,15],[21,26,30],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":11},"PROCEDURE","Supra-Sartorial Subcutaneous Infiltration (SSSI)","20 mL Ropivacaine or saline infiltrated subcutaneously from lateral to medial, superficial to vastus medialis and sartorius muscle, at femoral triangle apex using inject-as-you-advance technique, avoiding hyperechoic nerves.",[9,17],{"type":22,"name":27,"description":28,"armGroupLabels":29,"otherNames":11},"intermittent adductor canal block (iACB)","A single-shot adductor canal block is first performed post-operatively with 20 mL 0.3% Ropivacaine at the level of femoral triangle apex before inserting a catheter into the canal. The following doses (20 mL each time) start at 9:00 PM on the day of surgery and are intermittently given every 12 hours until day 4.",[9,17],{"type":22,"name":31,"description":32,"armGroupLabels":33,"otherNames":11},"posterior capsule local infiltration analgesia (PC-LIA)","PC-LIA consists of two 10 mL injections of 0.3% ropivacaine delivered intraoperatively to the posteromedial and posterolateral aspects of the posterior capsule before cementation. The target injection plane is the potential space between the posterior capsule and the popliteal artery.",[9,17],[35],{"name":36,"role":37,"phone":38,"phoneExt":11,"email":39},"Shang-Ru Yeoh, MD, MSc","CONTACT","+886-987-850-411","sr.yeoh@gmail.com",[41],{"facility":42,"status":11,"city":43,"state":11,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":11},"Taipei Municipal Wanfang Hospital","Taipei","116","Taiwan","TW",{"type":48,"coordinates":49},"Point",[50,51],121.52639,25.05306,{"lat":51,"lon":50},{"type":54,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100607700","efficacy-of-an-afcn-proxy-block-in-post-tka-multimodal-pain-management-100607700",false,"NCT07191964","Efficacy of an AFCN Proxy Block in Post-TKA Multimodal Pain Management","Efficacy Assessment of Supra-Sartorial Subcutaneous Infiltration (SSSI) as an Anterior Femoral Cutaneous Nerve Proxy Block in the Multimodal Pain Management After Total Knee Arthroplasty: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Adults aged 45-90 undergoing unilateral primary TKA for osteoarthritis.\n* American Society of Anesthesiologists (ASA) physical status I-III.\n* Able to provide informed consent and use NRS pain scales.\n* Surgery scheduled to start before noon to standardize spinal anesthesia recovery.\n\nExclusion Criteria:\n\n* Bilateral or revision TKA.\n* Contraindications to regional anesthesia (e.g., coagulopathy, infection at injection site).\n* Chronic opioid use (\\>30 mg morphine equivalents\u002Fday) or preoperative NRS \\>4.\n* Pre-existing neurological deficits in lower extremities or AFCN-related neuropathy.\n* Allergy to ropivacaine.\n* Pregnancy, breastfeeding, or cognitive impairment affecting assessments.","ALL","45 Years","90 Years",{"count":66,"type":67},90,"ESTIMATED","INTERVENTIONAL",[70],"NA","This randomized controlled trial evaluates the additive effect of Supra-Sartorial Subcutaneous Infiltration (SSSI) when performed in combination with intermittent adductor canal block (iACB) and posterior capsule local infiltration analgesia (PC-LIA) for pain management after total knee arthroplasty (TKA). SSSI, an easy-to-perform tentative proxy block to targeted anterior femoral cutaneous nerve (AFCN) block, is tested in 90 adults (45-90 years) randomized into two arms: active SSSI versus sham SSSI. Primary outcome is pain scores at rest and during movement on postoperative day 0; secondary outcomes include daily pain trajectory at rest and during movement, functional recovery scores, rescue analgesic doses over days 0-3, and quality of recovery assessment on day 4.",[73],"Postoperative Pain Management in Total Knee Arthroplasty",[75,76],"Anterior Femoral Cutaneous Nerve Block","Total Knee Arthroplasty","NOT_YET_RECRUITING","2026-06-29",{"date":80,"type":81},"2026-07-01","ACTUAL",{"date":83,"type":67},"2026-08-01",{"date":85,"type":67},"2027-09-01",{"name":5,"class":6},1]