[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100637605":3},{"organization":4,"armGroups":7,"interventions":26,"overallOfficials":30,"centralContacts":37,"locations":43,"responsibleParty":62,"collaborators":30,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":30,"eligibilityCriteria":72,"healthyVolunteers":68,"sex":73,"minAge":74,"maxAge":75,"enrollmentInfo":76,"targetDuration":30,"studyType":79,"phases":80,"briefSummary":82,"conditions":83,"keywords":30,"overallStatus":87,"whyStopped":30,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"Universidade Federal do Para","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Placebo","PLACEBO_COMPARATOR","The placebo group received an application of placebo gel for the control of post-bleaching tooth sensitivity.",[13],"Other: Placebo",{"label":15,"type":16,"description":17,"interventionNames":18},"KF2 - Potassium nitrate","ACTIVE_COMPARATOR","The KF2 group received an application of 5% potassium nitrate and 2% sodium fluoride for the control of post-bleaching tooth sensitivity.",[19],"Other: KF2 - Potassium nitrate",{"label":21,"type":22,"description":23,"interventionNames":24},"Jucá - Libidibia ferrea gel","EXPERIMENTAL","The Jucá group received an experimental 0.5% Libidibia ferrea gel for the control of post-bleaching tooth sensitivity.",[25],"Other: Jucá - Libidibia ferrea gel",[27,31,34],{"type":6,"name":9,"description":28,"armGroupLabels":29,"otherNames":30},"Before bleaching treatment with 35% hydrogen peroxide, participants in the placebo group received a placebo gel without active ingredients, applied under the same conditions described for the experimental gel.",[9],null,{"type":6,"name":15,"description":32,"armGroupLabels":33,"otherNames":30},"Prior to bleaching treatment with 35% hydrogen peroxide, participants in the KF2 group will receive an application of a desensitizing gel containing 5% potassium nitrate and 2% sodium fluoride on the labial surfaces of the maxillary and mandibular central incisors, lateral incisors, and canines, and on the buccal surfaces of the maxillary and mandibular premolars, for 10 minutes.",[15],{"type":6,"name":21,"description":35,"armGroupLabels":36,"otherNames":30},"Prior to bleaching treatment with 35% hydrogen peroxide, participants in the Jucá group will receive an application of the experimental 0.5% Libidibia ferrea gel on the labial surfaces of the maxillary and mandibular central incisors, lateral incisors, and canines, and on the buccal surfaces of the maxillary and mandibular premolars, for 10 minutes.",[21],[38],{"name":39,"role":40,"phone":41,"phoneExt":30,"email":42},"Cecy M Silva","CONTACT","+55 (91) 3201-7563","cecymsilva@gmail.com",[44],{"facility":45,"status":30,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"UFPA","Belém","Pará","66075-110","Brazil","BR",{"type":52,"coordinates":53},"Point",[54,55],-48.50444,-1.45583,{"lat":55,"lon":54},[58],{"name":59,"role":40,"phone":60,"phoneExt":30,"email":61},"Federal University of Pará","55(91) 3201-7390","ppgo@ufpa.br",{"type":63,"investigatorFullName":64,"investigatorTitle":65,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"PRINCIPAL_INVESTIGATOR","Cecy Martins Silva","Professor of the Graduate Program in Dentistry at the Federal University of Pará","100637605","efficacy-of-an-experimental-gel-based-on-libidibia-ferrea-on-post-bleaching-tooth-sensitivity-100637605",false,"NCT07599514","Efficacy of an Experimental Gel Based on Libidibia Ferrea on Post-bleaching Tooth Sensitivity","Efficacy of an Experimental Gel Based on Libidibia Ferrea in Controlling Post-bleaching Tooth Sensitivity: a Randomized Clinical Trial.","Inclusion Criteria:\n\nGood oral hygiene; Absence of active caries lesions; No previous tooth bleaching treatment; Absence of dental hypersensitivity; Not being pregnant; Presence of at least 28 teeth in the oral cavity.\n\nExclusion Criteria:\n\nVolunteers undergoing orthodontic treatment; Presence of periodontal disease; Dental cracks or fractures; Restorations or prostheses on anterior teeth; Extensive restorations in molars; Gastroesophageal disorders; Severe intrinsic tooth discoloration; Presence of dentin exposure in anterior and\u002For posterior teeth.","ALL","18 Years","40 Years",{"count":77,"type":78},75,"ESTIMATED","INTERVENTIONAL",[81],"NA","This randomized, parallel, single-blind, placebo-controlled clinical trial aims to investigate the effects of an experimental 0.5% Libidibia ferrea gel on the control of post-bleaching tooth sensitivity and its influence on bleaching efficacy. Seventy-five selected volunteers will be randomly allocated into three groups: CT (placebo gel), KF2 (5% potassium nitrate and 2% sodium fluoride), and JUC (experimental Libidibia ferrea gel). Each group will receive the corresponding desensitizing treatment, and the assigned product will be actively applied to the labial surfaces of the anterior teeth and the buccal surfaces of the first premolars for 10 minutes. Subsequently, all groups will undergo an in-office tooth bleaching protocol with 35% hydrogen peroxide, consisting of two sessions with three 15-minute applications each, with a 7-day interval between sessions. Postoperative sensitivity will be recorded daily by the patients for 14 days using a visual analog scale (VAS), while tooth color will be measured using a spectrophotometer at baseline and one week after the end of treatment. Data will be subjected to statistical analysis according to sample distribution, with a statistical power of 80% and a significance level of 5%.",[84,85,86],"Tooth Bleaching","Pain","Dentin Desensitizing Agents","NOT_YET_RECRUITING","2026-05-19",{"date":90,"type":91},"2026-05-22","ACTUAL",{"date":93,"type":78},"2026-06-13",{"date":95,"type":78},"2027-03-30",{"name":5,"class":6},1]