[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100600024":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":29,"locations":35,"responsibleParty":55,"collaborators":26,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":26,"eligibilityCriteria":63,"healthyVolunteers":59,"sex":64,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":26,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":76,"overallStatus":38,"whyStopped":26,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"The First Affiliated Hospital with Nanjing Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Auricular acupuncture treatment group","EXPERIMENTAL","On the basis of conventional nursing, patients are treated with bilateral auricular acupuncture points (Seirin Pyonex Needles φ 0.2 mm × 1.2 mm) before chemotherapy.\n\nSpecific operation: 1 treatment before each chemotherapy treatment, and 2 treatments a week in the 2nd and 3rd weeks of the chemotherapy interval. The patient was instructed to press the acupuncture point for 3 times\u002Fd, the pressure time was 5min, and the local swelling pain was tolerated by the patient. The doctor took the needle out for the patient after leaving it for 3 days. Treatment was continued for 4 cycles of chemotherapy, followed up for 2 months after treatment completion, and routine care was carried out during treatment.",[13],"Device: Auricular acupuncture treatment",{"label":15,"type":16,"description":17,"interventionNames":18},"Sham acupuncture group","SHAM_COMPARATOR","The treatment regimen is the same as that of the auricular acupuncture treatment group, but with a sham acupuncture (Seirin Pyonex Needles).",[19],"Device: Sham acupuncture group",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Auricular acupuncture treatment","Auricular acupuncture is an innovative intradermal acupuncture, which can directly use the meridian system of the ear skin to directly transmit the received stimulation to the lesion. Its stimulation time is long, and the amount of stimulation is strong. Studies have shown that needle pricking continuously delivers an adequate dose of acupuncture stimulation by continuously stimulating Aβ, Aδ, and\u002For C afferent fibers from the skin and transmitting them to the brain nucleus through the ventrolateral cord of the spinal cord. It is also believed that by stimulating the cranial nerves, especially the auricular branch of the vagus nerve, the effect of sensory afferent peripheral stimulation can be enhanced, and the analgesic effect of the auricular acupoints can be achieved.",[9],null,{"type":22,"name":15,"description":17,"armGroupLabels":28,"otherNames":26},[15],[30],{"name":31,"role":32,"phone":33,"phoneExt":26,"email":34},"Wei Li, Ph.D","CONTACT","025-68307102","real.lw@163.com",[36],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Jiangsu Provincial People's Hospital","RECRUITING","Nanjing","Jiangsu","210000","China","CN",{"type":45,"coordinates":46},"Point",[47,48],118.77778,32.06167,{"lat":48,"lon":47},[51,53],{"name":31,"role":32,"phone":52,"phoneExt":26,"email":34},"25-68307102",{"name":31,"role":54,"phone":26,"phoneExt":26,"email":26},"PRINCIPAL_INVESTIGATOR",{"type":56,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100600024","efficacy-of-auricular-acupuncture-therapy-in-the-prevention-of-cipn-in-breast-cancer-100600024",false,"NCT07092111","Efficacy of Auricular Acupuncture Therapy in the Prevention of CIPN in Breast Cancer","Efficacy of Auricular Acupuncture Therapy Via the Seirin Pyonex Needles in the Prevention of Chemotherapy-Induced Peripheral Neuropathy(CIPN) in Breast Cancer","Inclusion Criteria:\n\n* Patients with breast cancer diagnosed with stage I-III;\n* Planned to receive 4 cycles of taxane chemotherapy and have not taken neurostable drugs within three months;\n* 18 years old≤ age≤ 75 years old, female;\n* Subjects voluntarily participate in this trial and sign the informed consent form.\n\nExclusion Criteria:\n\n* Patients who have had acupuncture treatment in the past;\n* After examination by a doctor, there is a local infection at or near the acupuncture site, which is not suitable for acupuncture.\n* Platelets\\\u003C 50,000\u002FμL;\n* Patients with CIPN≥1 grade 1 (NCI-CTCAE);\n* Peripheral neuropathy or other neuropathic pain caused by diabetes mellitus or other factors related to HIV infection.","FEMALE","18 Years","75 Years",{"count":68,"type":69},110,"ESTIMATED","INTERVENTIONAL",[72],"NA","Evaluate the Efficacy of Auricular Acupuncture Therapy via the Seirin Pyonex Needles in the Prevention of Chemotherapy-Induced Peripheral Neuropathy in Breast Cancer",[75],"Chemotherapy-Induced Peripheral Neuropathy in Breast Cancer",[77,78,79],"chemotherapy-induced peripheral neuropathy","auricular acupuncture","breast cancer","2025-07-21",{"date":82,"type":83},"2025-07-29","ACTUAL",{"date":85,"type":83},"2024-07-01",{"date":87,"type":69},"2025-09",{"name":5,"class":6},1]