[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100630509":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":22,"centralContacts":27,"locations":34,"responsibleParty":55,"collaborators":32,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":32,"eligibilityCriteria":65,"healthyVolunteers":61,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":32,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":32,"overallStatus":37,"whyStopped":32,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Assiut University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Behavioral Therapy for chronic cough","EXPERIMENTAL","About 30 patients suffering from chronic cough persisting for more than eight weeks that is refractory to standard medical treatment for common causes of chronic cough, including asthma, gastroesophageal reflux disease",[13],"Behavioral: Behavioral Therapy",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"BEHAVIORAL","Behavioral Therapy","to evaluate the efficacy of behavioral therapy for chronic cough in patients with laryngeal hyperresponsiveness in order to assess its role as a non-pharmacological management strategy. This will provide an efficient plan of therapy for such challenging condition.",[9],[21],"Laryngeal hyperresponsiveness",[23],{"name":24,"affiliation":25,"role":26},"Eman Sayed Hassan, Professor","Head of Phoniatric unit,ENT Department,Faculty of Medicine, Assiut University","STUDY_CHAIR",[28],{"name":29,"role":30,"phone":31,"phoneExt":32,"email":33},"Mohamed Shaaban Mohamed Mahfouz, Resident","CONTACT","+201094817965",null,"mhamedshaaban6@gmail.com",[35],{"facility":36,"status":37,"city":38,"state":32,"zip":32,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"Assuit University hospitals","RECRUITING","Asyut","Egypt","EG",{"type":42,"coordinates":43},"Point",[44,45],31.18368,27.18096,{"lat":45,"lon":44},[48,51],{"name":24,"role":30,"phone":49,"phoneExt":32,"email":50},"+201004082014","eshh2003@aun.edu.eg",{"name":52,"role":30,"phone":53,"phoneExt":32,"email":54},"Mohamed Fawzy Hassan, Professor","+201003032335","adam@aun.edu.eg",{"type":56,"investigatorFullName":57,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":32,"oldOrganization":32},"PRINCIPAL_INVESTIGATOR","Mohamed Shaaban Mohamed","Resident at of Phoniatric, ENT Department,Faculty of Medicine","100630509","efficacy-of-behavioral-therapy-for-chronic-refractory-cough-100630509",false,"NCT07488598","Efficacy of Behavioral Therapy for Chronic Refractory Cough","Efficacy of Behavioral Therapy for Chronic Refractory Cough in Patients With Laryngeal Hyperresponsiveness","Inclusion Criteria:\n\n* Eligible participants are adults aged ≥18 years i.e. normal chest radiograph.\n* participants with chronic cough persisting for more than eight weeks that is refractory to standard medical treatment for common causes of chronic cough, including asthma, gastroesophageal reflux disease .\n* Participants are required to exhibit clinical features suggestive of laryngeal hyperresponsiveness, such as cough triggered by phonation, laughter, cold air, or irritant exposure, with associated laryngeal symptoms including throat irritation, dysphonia, or frequent throat clearing.\n\nExclusion Criteria:\n\n* Patients are excluded if they are current smokers or had ceased smoking within six months\n* patients have evidence of active pulmonary or cardiac disease, recent respiratory tract infection, recent angiotensin-converting enzyme inhibitor use.\n* significant structural laryngeal pathology, neurological disorders affecting cough reflex control, or inability to comply with study procedures.\n* Head \\&neck pathology e.g sinusitis, glottal insufficiency or primary muscle tension dysphonia","ALL","18 Years","50 Years",{"count":70,"type":71},30,"ESTIMATED","INTERVENTIONAL",[74],"NA","Chronic cough is defined as cough persisting for more than eight weeks. It is a common clinical problem that significantly impairs patients' physical, psychological, and social quality of life. Chronic cough remains a diagnostic and therapeutic challenge despite systematic evaluation and treatment of common etiologies such as asthma, gastroesophageal reflux disease",[77],"Chronic Cough","2026-04-19",{"date":80,"type":81},"2026-04-23","ACTUAL",{"date":83,"type":81},"2026-03-10",{"date":85,"type":71},"2027-05-10",{"name":5,"class":6},1]