[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100602617":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":26,"responsibleParty":41,"collaborators":26,"id":43,"slug":44,"hasResults":45,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":45,"sex":51,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":26,"studyType":57,"phases":58,"briefSummary":60,"conditions":61,"keywords":65,"overallStatus":72,"whyStopped":26,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":26},{"fullName":5,"class":6},"Suez Canal University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Bioactive Glass Group","EXPERIMENTAL","Patients in this group will undergo maxillary sinus floor augmentation using bioactive glass bone graft material (UNIGRAFT, Biomed Inc., USA). The procedure will be performed via open sinus lift approach.",[13],"Device: Bioactive Glass Bone Graft (UNIGRAFT)",{"label":15,"type":16,"description":17,"interventionNames":18},"Xenograft Group","ACTIVE_COMPARATOR","Patients in this group will undergo maxillary sinus floor augmentation using a conventional xenograft material via open sinus lift approach.",[19],"Device: Xenograft Bone Graft (Bio-Oss)",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Bioactive Glass Bone Graft (UNIGRAFT)","A bioactive glass bone graft material (UNIGRAFT, Biomed Inc., USA) used for maxillary sinus floor augmentation via open sinus lift technique.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Xenograft Bone Graft (Bio-Oss)","A commercially available bovine-derived xenograft material (Bio-Oss, Geistlich Pharma) used for maxillary sinus floor augmentation via open sinus lift technique.",[15],[32],{"name":33,"affiliation":5,"role":34},"Mohamed A Elsholkamy, Professor","PRINCIPAL_INVESTIGATOR",[36],{"name":37,"role":38,"phone":39,"phoneExt":26,"email":40},"Mostafa A Elfeky, BDS","CONTACT","+201000543404","mostafa_elfeky@dent.suez.edu.eg",{"type":42,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100602617","efficacy-of-bioactive-glass-vs-xenograft-in-maxillary-sinus-augmentation-100602617",false,"NCT07125846","Efficacy of Bioactive Glass vs. Xenograft in Maxillary Sinus Augmentation","Clinical, Radiographic and Histologic Assessment of the Efficacy of Bioactive Glass as a Novel Grafting Material in Maxillary Sinus Floor Augmentation: A Randomized Controlled Study","BIOXENO","Inclusion Criteria:\n\n* Patients requiring maxillary sinus floor augmentation for dental implant placement.\n* Residual alveolar bone height ≤ 4 mm in posterior maxilla (SA4 classification).\n* Age between 20 to 65 years.\n* Good general health and able to attend scheduled follow-up visits.\n* Signed written informed consent.\n\nExclusion Criteria:\n\n* Presence of systemic conditions that could affect bone healing (e.g., uncontrolled diabetes, osteoporosis).\n\nHistory of radiotherapy in the head and neck region.\n\n* Heavy smoking (more than 10 cigarettes\u002Fday).\n* Active sinus pathology or previous sinus surgery.\n* Pregnant or breastfeeding women.\n* Use of medications affecting bone metabolism (e.g., bisphosphonates or corticosteroids).\n* Poor oral hygiene or untreated periodontal disease.","ALL","20 Years","65 Years",{"count":55,"type":56},20,"ESTIMATED","INTERVENTIONAL",[59],"NA","This randomized controlled study aims to evaluate the clinical, radiographic, and histologic efficacy of using bioactive glass bone graft (UNIGRAFT by Biomed Inc., USA) compared to a conventional xenograft in maxillary sinus augmentation procedures. A total of 20 patients classified as SA4 according to the Misch classification will be enrolled and randomly allocated into two groups. Outcomes will be assessed using Cone Beam Computed Tomography (CBCT) for vertical bone gain and, where applicable, histologic analysis. The study is conducted at the Faculty of Dentistry, Suez Canal University.",[62,63,64],"Alveolar Bone Loss","Maxillary Sinus Disease","Tooth Loss",[66,67,68,69,70,71],"Maxillary Sinus Augmentation","Bioactive Glass","Xenograft","Sinus Lift","Bone Grafting","Dental Implant","NOT_YET_RECRUITING","2025-08-14",{"date":75,"type":76},"2025-08-15","ACTUAL",{"date":78,"type":56},"2025-10-15",{"date":80,"type":56},"2026-04-01",{"name":5,"class":6}]