[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100582704":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":22,"centralContacts":27,"locations":32,"responsibleParty":49,"collaborators":10,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":11,"healthyVolunteers":53,"sex":58,"minAge":59,"maxAge":10,"enrollmentInfo":60,"targetDuration":10,"studyType":63,"phases":10,"briefSummary":64,"conditions":65,"keywords":67,"overallStatus":35,"whyStopped":10,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"Instituto de Investigacion Sanitaria La Fe","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Study cohort",null,"Inclusion Criteria:\n\n* patients with AAA under follow-up who are going to be treated with EVAR.\n* signed informed consent to perform CTA, CEUS and for the determination of biomarkers.\n\nExclusion Criteria:\n\n* patients with inflammatory abdominal aortic aneurysms or ruptured aneurysm.",[13],"Diagnostic Test: CTA",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DIAGNOSTIC_TEST","CTA","The levels of biomarkers are determined before (within 30 days prior to the procedure) and after the implantation of the stent (24-48 hours, 1 month, 3 months, 6 months, and at 1 year), along with the performance of a contrast-enhanced ultrasound. Additionally, a follow-up CT angiography is performed to validate the concordance, that is, to assess if there are changes in the biomarker values determined one month after the implantation of the stent compared to the baseline values that may suggest the presence of complications (endoleaks, infection, thrombosis, etc.).",[9],[21],"Ultrasound image enhancement",[23],{"name":24,"affiliation":25,"role":26},"Juan Manuel Sanchís García","Hospital Universitario La Fe","PRINCIPAL_INVESTIGATOR",[28],{"name":24,"role":29,"phone":30,"phoneExt":10,"email":31},"CONTACT","+34 961245655","sanchis_juagar@gva.es",[33],{"facility":34,"status":35,"city":36,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"Hospital La Fe","RECRUITING","Valencia","46026","Spain","ES",{"type":41,"coordinates":42},"Point",[43,44],-0.37966,39.47391,{"lat":44,"lon":43},[47],{"name":24,"role":29,"phone":48,"phoneExt":10,"email":31},"+34961245655",{"type":50,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100582704","efficacy-of-biomarkers-and-ceus-versus-cta-in-aaa-follow-up-post-evar-100582704",false,"NCT06866769","Efficacy of Biomarkers and CEUS Versus CTA in AAA Follow-up Post-EVAR","Comparación De La Eficacia Entre Biomarcadores Y Ecografía Con Contraste Frente a Angio-TC En El Seguimiento De Aneurismas De Aorta Abdominal (AAA) Tras Reparación Endovascular (EVAR)","EVAR-markers","ALL","18 Years",{"count":61,"type":62},60,"ESTIMATED","OBSERVATIONAL","This prospective observational study evaluates the efficacy of contrast-enhanced ultrasound and biomarker determination in the follow-up of patients with abdominal aortic aneurysm (AAA) treated with Endovascular Aneurysm Repair (EVAR). Currently, computed tomography angiography (CTA) is the standard for follow-up, although it has disadvantages such as radiation exposure and the use of iodinated contrasts. Contrast-enhanced ultrasound (CEUS), free of radiation and nephrotoxicity, and biomarkers could reduce the need for CTA minimizing the associated risks. Biomarkers will be measured before and after EVAR and CEUS will be performed at various time points and compared with CTA results to validate concordance and effectiveness in detecting endoleaks and aneurysm remodeling. The objectives include determining the efficacy of these combined methods and establishing a follow-up protocol that reduces exposure to radiation and iodinated contrast agents.",[66],"Abdominal Aortic Aneurysm Without Rupture",[68,69,70,71,72],"Abdominal Aortic Aneurysm (AAA)","Endovascular Aneurysm Repair (EVAR)","Contrast-enhanced ultrasound (CEUS)","Computed tomography angiography (CTA)","Biomarkers.","2025-03-05",{"date":75,"type":76},"2025-03-10","ACTUAL",{"date":78,"type":76},"2024-07-25",{"date":80,"type":62},"2028-04-30",{"name":5,"class":6},1]