[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100615935":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":30,"locations":36,"responsibleParty":232,"collaborators":25,"id":234,"slug":235,"hasResults":236,"nctId":237,"briefTitle":238,"officialTitle":239,"acronym":240,"eligibilityCriteria":241,"healthyVolunteers":236,"sex":242,"minAge":243,"maxAge":25,"enrollmentInfo":244,"targetDuration":25,"studyType":247,"phases":248,"briefSummary":250,"conditions":251,"keywords":255,"overallStatus":177,"whyStopped":25,"lastUpdateSubmitDate":259,"lastUpdatePostDateStruct":260,"startDateStruct":263,"completionDateStruct":264,"leadSponsor":266,"locationsCount":267},{"fullName":5,"class":6},"University Hospital, Bordeaux","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Standard colonoscopy","PLACEBO_COMPARATOR","Patients will be enrolled after a pre-colonoscopy consultation and risk-assessment for colorectal cancer. The screening colonoscopy will be performed by an investigator. Patients will be randomized in the endoscopy room after confirmed cecal intubation and quality of bowel preparation. Patient has standard colonoscopy",[13],"Procedure: Standard colonoscopy",{"label":15,"type":16,"description":17,"interventionNames":18},"Colonoscopy with CADe","ACTIVE_COMPARATOR","Patients will be enrolled after a pre-colonoscopy consultation and risk-assessment for colorectal cancer. The screening colonoscopy will be performed by an investigator. Patients will be randomized in the endoscopy room after confirmed cecal intubation and quality of bowel preparation. Patient has colonoscopy with CADe (CAD EYE or GENIUS)",[19],"Procedure: Colonoscopy CADe",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Colonoscopy standard (without CADe)",[9],null,{"type":22,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Colonoscopy CADe","colonoscopy with CADe",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Arthur BERGER, MD","CONTACT","+335 57 67 49 31","arthur.berger@chu-bordeaux.fr",[37,58,73,88,103,118,133,148,163,175,188,203,217],{"facility":38,"status":39,"city":40,"state":25,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"CH de la Côte Basque","NOT_YET_RECRUITING","Bayonne","64100","France","FR",{"type":45,"coordinates":46},"Point",[47,48],-1.473,43.49316,{"lat":48,"lon":47},[51,55],{"name":52,"role":33,"phone":53,"phoneExt":25,"email":54},"Felix GOUTORBE, MD","+33 5.59.44.31.36","f.goutorbe@ch-cotebasque.fr",{"name":56,"role":57,"phone":25,"phoneExt":25,"email":25},"Félix GOUTORBE, MD","PRINCIPAL_INVESTIGATOR",{"facility":59,"status":39,"city":60,"state":25,"zip":61,"country":42,"countryCode":43,"cosmosGeoPoint":62,"geoPoint":66,"contacts":67},"CHU Brest la Cavale Blanche","Brest","29200",{"type":45,"coordinates":63},[64,65],-4.48628,48.39029,{"lat":65,"lon":64},[68,72],{"name":69,"role":33,"phone":70,"phoneExt":25,"email":71},"Lucille QUENEHERVE, MD","+332.98.34.71.16","lucille.queneherve@chu-brest.fr",{"name":69,"role":57,"phone":25,"phoneExt":25,"email":25},{"facility":74,"status":39,"city":75,"state":25,"zip":76,"country":42,"countryCode":43,"cosmosGeoPoint":77,"geoPoint":81,"contacts":82},"Clinique Paris Bercy","Charenton-le-Pont","94220",{"type":45,"coordinates":78},[79,80],2.41217,48.82209,{"lat":80,"lon":79},[83,87],{"name":84,"role":33,"phone":85,"phoneExt":25,"email":86},"David KARSENTI, MD","+331.43.96.78.34","karsenti.paris@gmail.com",{"name":84,"role":57,"phone":25,"phoneExt":25,"email":25},{"facility":89,"status":39,"city":90,"state":25,"zip":91,"country":42,"countryCode":43,"cosmosGeoPoint":92,"geoPoint":96,"contacts":97},"CHU de Limoges","Limoges","87042",{"type":45,"coordinates":93},[94,95],1.24759,45.83362,{"lat":95,"lon":94},[98,102],{"name":99,"role":33,"phone":100,"phoneExt":25,"email":101},"Rémi COLLIN, MD","+335.55.05.55.55","remi.collin@chu-limoges.com",{"name":99,"role":57,"phone":25,"phoneExt":25,"email":25},{"facility":104,"status":39,"city":105,"state":25,"zip":106,"country":42,"countryCode":43,"cosmosGeoPoint":107,"geoPoint":111,"contacts":112},"Institut Paoli Calmettes","Marseille","13009",{"type":45,"coordinates":108},[109,110],5.38107,43.29695,{"lat":110,"lon":109},[113,117],{"name":114,"role":33,"phone":115,"phoneExt":25,"email":116},"Jean-Philippe RATONE, MD","+334 91 22 35 68","ratonej@ipc.unicancer.fr",{"name":114,"role":57,"phone":25,"phoneExt":25,"email":25},{"facility":119,"status":39,"city":120,"state":25,"zip":121,"country":42,"countryCode":43,"cosmosGeoPoint":122,"geoPoint":126,"contacts":127},"Clinique Jules Verne","Nantes","44300",{"type":45,"coordinates":123},[124,125],-1.55336,47.21725,{"lat":125,"lon":124},[128,132],{"name":129,"role":33,"phone":130,"phoneExt":25,"email":131},"Bertrand BRIEAU, MD","+332.51.17.34.00","bertrand.brieau@gmail.com",{"name":129,"role":57,"phone":25,"phoneExt":25,"email":25},{"facility":134,"status":39,"city":135,"state":25,"zip":136,"country":42,"countryCode":43,"cosmosGeoPoint":137,"geoPoint":141,"contacts":142},"CHU Nîmes","Nîmes","30029",{"type":45,"coordinates":138},[139,140],4.35788,43.83665,{"lat":140,"lon":139},[143,147],{"name":144,"role":33,"phone":145,"phoneExt":25,"email":146},"Ludovic CAILLO, MD","+334.66.68.31.83","ludovic.caillo@chu-nimes.fr",{"name":144,"role":57,"phone":25,"phoneExt":25,"email":25},{"facility":149,"status":39,"city":150,"state":25,"zip":151,"country":42,"countryCode":43,"cosmosGeoPoint":152,"geoPoint":156,"contacts":157},"APHP - Hôpital Saint Antoine","Paris","75012",{"type":45,"coordinates":153},[154,155],2.3488,48.85341,{"lat":155,"lon":154},[158,162],{"name":159,"role":33,"phone":160,"phoneExt":25,"email":161},"Xavier DRAY, MD","+331.49.28.27.10","xavier.dray@aphp.fr",{"name":159,"role":57,"phone":25,"phoneExt":25,"email":25},{"facility":164,"status":39,"city":150,"state":25,"zip":165,"country":42,"countryCode":43,"cosmosGeoPoint":166,"geoPoint":168,"contacts":169},"Aphp-Hegp","75015",{"type":45,"coordinates":167},[154,155],{"lat":155,"lon":154},[170,174],{"name":171,"role":33,"phone":172,"phoneExt":25,"email":173},"Guillaume PERROD, MD","+331.56.09.57.00","guillaume.perrod@aphp.fr",{"name":171,"role":57,"phone":25,"phoneExt":25,"email":25},{"facility":176,"status":177,"city":178,"state":25,"zip":179,"country":42,"countryCode":43,"cosmosGeoPoint":180,"geoPoint":184,"contacts":185},"CHU Bordeaux - Hôpital Haut Lévêque","RECRUITING","Pessac","33604",{"type":45,"coordinates":181},[182,183],-0.6324,44.80565,{"lat":183,"lon":182},[186,187],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},{"name":32,"role":57,"phone":25,"phoneExt":25,"email":25},{"facility":189,"status":39,"city":190,"state":25,"zip":191,"country":42,"countryCode":43,"cosmosGeoPoint":192,"geoPoint":196,"contacts":197},"CHU de Rennes","Rennes","35000",{"type":45,"coordinates":193},[194,195],-1.67431,48.11109,{"lat":195,"lon":194},[198,202],{"name":199,"role":33,"phone":200,"phoneExt":25,"email":201},"Timothée WALLENHORST, MD","+332.99.28.43.21","timothee.wallenhorst@chu-rennes.fr",{"name":199,"role":57,"phone":25,"phoneExt":25,"email":25},{"facility":204,"status":39,"city":205,"state":25,"zip":206,"country":42,"countryCode":43,"cosmosGeoPoint":207,"geoPoint":211,"contacts":212},"Clinique Pasteur","Toulouse","31076",{"type":45,"coordinates":208},[209,210],1.44367,43.60426,{"lat":210,"lon":209},[213,216],{"name":214,"role":33,"phone":160,"phoneExt":25,"email":215},"Mathieu GUIVARCH, MD","mguivarch@clinique-pasteur.com",{"name":214,"role":57,"phone":25,"phoneExt":25,"email":25},{"facility":218,"status":39,"city":219,"state":25,"zip":220,"country":42,"countryCode":43,"cosmosGeoPoint":221,"geoPoint":225,"contacts":226},"CHRU de Nancy - Hôpital Brabois Adultes","Vandœuvre-lès-Nancy","54511",{"type":45,"coordinates":222},[223,224],6.17114,48.66115,{"lat":224,"lon":223},[227,231],{"name":228,"role":33,"phone":229,"phoneExt":25,"email":230},"Marion SCHAEFER, MD","+333.83.15.41.49","m.schaefer@chru-nancy.fr",{"name":228,"role":57,"phone":25,"phoneExt":25,"email":25},{"type":233,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100615935","efficacy-of-cad-in-screening-colonoscopy-to-reduce-the-risk-of-advanced-adenoma-at-3-years-100615935",false,"NCT07299071","Efficacy of CAD in Screening Colonoscopy to Reduce the Risk of Advanced Adenoma at 3 Years.","Randomized Controlled Trial Evaluating the Efficacy of CAD in Screening Colonoscopy to Reduce the Risk of Advanced Adenoma at 3 Years.","IA-COLO 2","Inclusion Criteria:\n\n* Patients over 18 years of age with indication for colonoscopy as part of a screening program, after a positive immunological (FIT) test, and\u002For for personal or family history of colorectal cancer and\u002For personal history of colonic adenomas,\n* Written informed consent signed\n* Patients covered by a health-care insurance.\n\nExclusion Criteria:\n\n* Failed complete colonoscopy, defined by the absence of cecal intubation and\u002For the absence of terminal ileum cauterization\n* Inadequate bowel preparation (Boston bowel preparation score \\\u003C 6, and\u002For least at one part of colon with score ≤ 1)\n* An infiltrative tumor was diagnosed during colonoscope insertion time, not accessible to endoscopic resection and likely to require surgical management (a procedure where part of the colon may need to be removed).\n* Patient under guardianship or protection\n* Pregnant women\n* Not fluent in French or illiterate\n* Personal history of inflammatory bowel disease\n* Personal history of genetic predisposition of CRC\n* Personal history of colonic surgery","ALL","18 Years",{"count":245,"type":246},592,"ESTIMATED","INTERVENTIONAL",[249],"NA","The occurrence of interval cancers after colonoscopy raises the possibility of missed lesions. High- performance computer aided diagnosis (CAD) systems have been specially designed for the detection of colorectal lesions (CAD for detection is named CADe). The use of CADe improves adenoma detection in screening colonoscopy. The potential of CADe system in reducing the rate of progression to advanced polyps or interval cancer between two colonoscopies remains still uncertain.",[252,253,254],"Colonoscopy","Colorectal Neoplasms","Intestinal Polyps",[256,257,258],"colonoscopy","colorectal neoplasms","computer aided diagnosis","2026-03-13",{"date":261,"type":262},"2026-03-16","ACTUAL",{"date":259,"type":262},{"date":265,"type":246},"2031-03",{"name":5,"class":6},13]