[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100604598":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":37,"locations":43,"responsibleParty":63,"collaborators":25,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":25,"eligibilityCriteria":72,"healthyVolunteers":68,"sex":73,"minAge":74,"maxAge":75,"enrollmentInfo":76,"targetDuration":25,"studyType":79,"phases":80,"briefSummary":82,"conditions":83,"keywords":85,"overallStatus":46,"whyStopped":25,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"University of Nove de Julho","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Microneedling","ACTIVE_COMPARATOR","Microneedling performed with an electronic pen and sterile disposable cartridge of 12 needles at 2mm depth",[13],"Device: Microneedling",{"label":15,"type":16,"description":17,"interventionNames":18},"Fractionated Er:Glass and Thulium Lasers","EXPERIMENTAL","Fractional Erbium:Glass laser is applied first, focused on scarred areas, followed immediately by fractional Thulium 1927 nm over the full face.",[19],"Device: Fractionated Er:Glass Laser combined to Fractionated Thulium Laser",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","Microneedling performed with an electronic pen and sterile disposable cartridge with 12 needles and 2mm depth, three treatment sessions at four-week intervals.",[9],null,{"type":22,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Fractionated Er:Glass Laser combined to Fractionated Thulium Laser","Fractional Erbium:Glass laser will be applied first, focused on scarred areas (50 mJ, 15 ms e 100 PPA) , followed immediately by fractional Thulium 1927 nm over the full face (10 mJ, 1 ms e 100 PPA), three treatment sessions at four-week intervals.",[15],[31,34],{"name":32,"affiliation":5,"role":33},"Christiane Pavani, PhD","STUDY_CHAIR",{"name":35,"affiliation":5,"role":36},"Luciana Khachikian, Master Student","PRINCIPAL_INVESTIGATOR",[38],{"name":39,"role":40,"phone":41,"phoneExt":25,"email":42},"Luciana Khachikian, Master student","CONTACT","+5511989969924","lucianacamargo@uni9.edu.br",[44],{"facility":45,"status":46,"city":47,"state":25,"zip":25,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"Espaço Conceito Medical San","RECRUITING","São Paulo","Brazil","BR",{"type":51,"coordinates":52},"Point",[53,54],-46.63611,-23.5475,{"lat":54,"lon":53},[57,61],{"name":58,"role":40,"phone":59,"phoneExt":25,"email":60},"Luciana C Khachikian","+5511983313093","mestrado.lucianakha@gmail.com",{"name":62,"role":36,"phone":25,"phoneExt":25,"email":25},"Luciana Camargo Khachikian",{"type":36,"investigatorFullName":64,"investigatorTitle":65,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Christiane Pavani","Randomized Controlled Trial Comparing Combined Fractional Erbium:Glass and Thulium Lasers Versus Microneedling for the Treatment of Atrophic Acne Scars","100604598","efficacy-of-combined-fractional-erglass-and-thulium-lasers-versus-microneedling-for-atrophic-acne-scars-100604598",false,"NCT07151599","Efficacy of Combined Fractional Er:Glass and Thulium Lasers Versus Microneedling for Atrophic Acne Scars","Randomized Controlled Trial Comparing Fractional Erbium:Glass (1540-1550 nm) and Thulium (1927 nm) Lasers Versus Microneedling for the Treatment of Atrophic Acne Scars","Inclusion Criteria:\n\n* Fitzpatrick skin phototypes I to VI\n* Presence of atrophic acne scars on the face\n\nExclusion Criteria:\n\n* Decompensated systemic diseases\n* Any active infection (e.g., viral such as herpes, bacterial, or fungal)\n* Pregnant or breastfeeding women\n* Presence of hypertrophic or keloid scars\n* Current use of anticoagulant or antiplatelet medications\n* History of hemophilia or coagulation disorders\n* Current use of anti-inflammatory drugs or corticosteroids\n* Use of retinoids, including isotretinoin, within the past 6 months\n* Exposure to sunlight within the past 15 days\n* Undergoing any aesthetic facial treatment or having undergone scar treatments in the facial region within 180 days prior to study initiation\n* Presence of active acne (occasional isolated lesions will not be considered exclusion criteria)","ALL","18 Years","45 Years",{"count":77,"type":78},84,"ESTIMATED","INTERVENTIONAL",[81],"NA","The purpose of this study is to compare two treatments for acne scars on the face. The study will test whether fractional lasers (Erbium:Glass and Thulium) lead to better improvement in acne scars than microneedling.",[84],"Acne Scars",[86,87,9,88,84],"Fractionated Erbium Glass Laser","Fractionated Thulium Laser","Percutaneous Induction of Collagen","2025-11-24",{"date":91,"type":92},"2025-11-26","ACTUAL",{"date":94,"type":92},"2025-10-16",{"date":96,"type":78},"2026-07",{"name":5,"class":6},1]