[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100626516":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":36,"centralContacts":37,"locations":43,"responsibleParty":58,"collaborators":36,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":36,"eligibilityCriteria":68,"healthyVolunteers":64,"sex":69,"minAge":36,"maxAge":70,"enrollmentInfo":71,"targetDuration":36,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":80,"overallStatus":46,"whyStopped":36,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"Ain Shams University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"High power laser therapy group","EXPERIMENTAL","Pediatric bone marrow transplantation patients with oral mucositis will receive high-power laser therapy once daily for four consecutive days. The laser parameters will be a wavelength of 660 to 970 nm, of power 3.2 w, pulsed at 50% duty cycle, spot size of 1 cm2, for 230 sec, defocused mode.",[13],"Device: high power laser therapy",{"label":15,"type":16,"description":17,"interventionNames":18},"Basic oral care group","ACTIVE_COMPARATOR","Pediatric bone marrow transplantation patients with oral mucositis will receive standard basic oral care. Local methods: mouth rinse chlorohexidine three times a day, sodium bicarbonate mouthwash.",[19],"Drug: Basic oral care",[21,29],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","high power laser therapy","high power laser therapy once daily for four consecutive days with wavelength 660 to 970 nm, power 3.2 w, and duration of 230 seconds at 50% duty cycle",[9],[27,28],"Laser biostimulation","Photobiomodulation therapy",{"type":30,"name":31,"description":32,"armGroupLabels":33,"otherNames":34},"DRUG","Basic oral care","patients will receive local methods: cholorohexidine mouthwash as well sodium bicarbonate mouthwash",[15],[35],"conventional therapy",null,[38],{"name":39,"role":40,"phone":41,"phoneExt":36,"email":42},"Asmaa Ayman Gabr, Teaching Assistant","CONTACT","+2 01095692889","Asmaagabr@dent.asu.edu.eg",[44],{"facility":45,"status":46,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":36},"Oncology and Bone marrow transplant unit, Children's hospital, Ain Shams University","RECRUITING","Cairo","Cairo Governorate","+2","Egypt","EG",{"type":53,"coordinates":54},"Point",[55,56],31.24967,30.06263,{"lat":56,"lon":55},{"type":59,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":36,"oldOrganization":36},"PRINCIPAL_INVESTIGATOR","Asmaa Ayman Mohammed Gabr","Teaching Assistant","100626516","efficacy-of-high-level-laser-therapy-in-managing-oral-mucositis-among-pediatric-patients-undergoing-hematopoietic-stem-cell-transplantation-100626516",false,"NCT07436650","Efficacy of High-Level Laser Therapy in Managing Oral Mucositis Among Pediatric Patients Undergoing Hematopoietic Stem Cell Transplantation","Efficacy of High-Level Laser Therapy in Managing Oral Mucositis Among Pediatric Patients Undergoing Hematopoietic Stem Cell Transplantation: A Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* Children under the age of 18 years undergoing bone marrow transplantation during the phase of oral mucositis.\n* Oral mucositis starting from grade II on the WHO scale for OM.\n* Willingness to undergo treatment for four consecutive days and to return for evaluation 7 and 11 days after enrolment.\n\nExclusion Criteria:\n\n* Previous treatment with photobiomodulation for oral mucositis.\n* Limited mouth opening less than 2 cm.\n* Presence of dysplastic oral lesions.\n* Radiotherapy in the head and neck area.\n* Vulnerable groups of patients or decision-impaired individuals as prisoners, handicapped and mentally retarded individuals","ALL","18 Years",{"count":72,"type":73},14,"ESTIMATED","INTERVENTIONAL",[76],"NA","The goal of this clinical trial is to learn if high-level laser therapy can manage oral mucositis in pediatric patients undergoing hematopoietic bone marrow transplantation. The main question it aims to answer is :\n\nIs high-level laser therapy effective as a treatment for oral mucositis in pediatric hemopoietic stem cell transplant patients? Researchers will compare patients receiving basic oral care to see the effect on the WHO oral mucositis scale.\n\nParticipants will be subjected to high level laser on lesion sites .",[79],"Oral Mucositis",[79,81,82],"High Level Laser Therapy","Hematopoietic Stem cell Transplant","2026-03-17",{"date":85,"type":86},"2026-03-19","ACTUAL",{"date":88,"type":86},"2025-06-15",{"date":90,"type":73},"2030-12",{"name":5,"class":6},1]