[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100557921":3},{"organization":4,"armGroups":7,"interventions":26,"overallOfficials":41,"centralContacts":46,"locations":53,"responsibleParty":67,"collaborators":32,"id":69,"slug":70,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":75,"eligibilityCriteria":76,"healthyVolunteers":71,"sex":77,"minAge":78,"maxAge":79,"enrollmentInfo":80,"targetDuration":32,"studyType":83,"phases":84,"briefSummary":86,"conditions":87,"keywords":89,"overallStatus":93,"whyStopped":32,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":103},{"fullName":5,"class":6},"Clinica Gema Leon","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients receiving non invasive neuromodulation treatment.","EXPERIMENTAL","Patients without previous pathology of any kind who have passed the Covid19 and have respiratory, neurological or musculoskeletal sequelae; who will receive non invasive neuromodulation treatment.",[13],"Device: Non invasive neuromodulation therapy",{"label":15,"type":16,"description":17,"interventionNames":18},"Patients receiving traditional treatment.","ACTIVE_COMPARATOR","Patients receiving only traditional therapy. Patients without previous pathology of any kind who have passed the Covid19 and have respiratory, neurological or musculoskeletal sequelae; who will receive treatment of traditional therapy.",[19],"Other: Manual therapy",{"label":21,"type":22,"description":23,"interventionNames":24},"Patients receiving placebo treatment.","PLACEBO_COMPARATOR","Patients receiving placebo. Patients without previous pathology of any kind who have passed the Covid19 and have respiratory, neurological or musculoskeletal sequelae; to those who will be administered placebo (device off, without emitting).",[25],"Device: Placebo with non invasive neuromodulation",[27,33,37],{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"DEVICE","Non invasive neuromodulation therapy","In the 4 studies, the intervention consisted of 15 sessions spread over 5 weeks.\n\nEach intervention lasted 60 minutes. The intensity will be programmed in all sessions at Low, following the Arndt-Schulz law. The treatment was distributed in 3 phases: phase 1 of preparation, phase 2 to reduce fatigue and phase 3 to enhance autonomic improvement.",[9],null,{"type":6,"name":34,"description":35,"armGroupLabels":36,"otherNames":32},"Manual therapy","Common manual therapy administered for said pathology by traditional physiotherapy and therapeutic exercise.",[15],{"type":28,"name":38,"description":39,"armGroupLabels":40,"otherNames":32},"Placebo with non invasive neuromodulation","In the 4 studies, the intervention consisted of 15 sessions spread over 5 weeks.\n\nEach intervention lasted 60 minutes. The treatment was carried out with the machine turned off.",[21],[42],{"name":43,"affiliation":44,"role":45},"GEMA LEÓN BRAVO","Departamento de Enfermería, Farmacología y Fisioterapia de la Universidad de Córdoba","PRINCIPAL_INVESTIGATOR",[47,51],{"name":43,"role":48,"phone":49,"phoneExt":32,"email":50},"CONTACT","+34667401116","gemafisio@gmail.com",{"name":43,"role":48,"phone":49,"phoneExt":32,"email":52},"gemaleonbravo@icloud.com",[54],{"facility":55,"status":32,"city":56,"state":57,"zip":58,"country":59,"countryCode":60,"cosmosGeoPoint":61,"geoPoint":66,"contacts":32},"Gema León Physiotherapy and Rehabilitation Clinic","Córdoba","Andalusia","14011","Spain","ES",{"type":62,"coordinates":63},"Point",[64,65],-4.77275,37.89155,{"lat":65,"lon":64},{"type":45,"investigatorFullName":43,"investigatorTitle":68,"investigatorAffiliation":5,"oldNameTitle":32,"oldOrganization":32},"Principal Investigator","100557921","efficacy-of-non-invasive-neuromodulation-treatments-for-covid-19-sequelae-100557921",false,"NCT06544395","Efficacy of Non-invasive Neuromodulation Treatments for COVID-19 Sequelae","Efficacy of Non-invasive Neuromodulation Treatments for Post-COVID-19 Sequelae in Patients With Musculoskeletal, Respiratory and Neurological Conditions Due to Impaired Taste and Smell.","COVID-19","Inclusion Criteria:\n\n* Patients between the ages of 18 and 60.\n* Patients with a positive diagnosis of COVID-19.\n* Patients with post-COVID-19 sequelae with musculoskeletal, respiratory or neurological symptoms due to taste or smell lasting at least 30 days, with no history of respiratory and\u002For neurological and\u002For musculoskeletal diseases.\n* Patients who signed the informed consent.\n\nExclusion criteria:\n\n* Patients aged before 18 years and after 60 years.\n* Healthy people with no history of neurological, neurological and\u002For respiratory and\u002For musculoskeletal diseases\n* Patients with secondary diseases that could directly affect the systems to be evaluated who were not diagnosed positive for COVID-19.","ALL","18 Years","60 Years",{"count":81,"type":82},104,"ESTIMATED","INTERVENTIONAL",[85],"NA","The goal of this clinical trial is to demonstrate the effectiveness of non-invasive Neuromodulation as a therapy in neurological, respiratory and musculoskeletal pathologies derived from the consequences of Covid-19. It will also estimate the impact of non-invasive neuromodulation treatment on the functionality and quality of life of patients with COVID-19 sequelae.The main question it aim to answer is:\n\n\\- Is non-invasive neuromodulation effective as a therapy in neurological, respiratory and musculoskeletal pathologies derived from the consequences of Covid-19.\n\nResearchers will compare non-invasive neuromodulation to a placebo (treatment with the machine turned off).\n\nParticipants will:\n\n* Be evaluated before starting treatment.\n* Be evaluated 3 weeks after.\n* Be evaluated at 5 weeks, or 15 sessions or completion of treatment.\n* Be evaluated 6 weeks after finishing the treatment or 11 weeks after starting treatment.",[88],"Covid-19 Recurrent",[90,91,92],"Covid-19","Non Invasive Neuromodulation","Smell","NOT_YET_RECRUITING","2025-09-17",{"date":96,"type":97},"2025-09-18","ACTUAL",{"date":99,"type":82},"2026-01-01",{"date":101,"type":82},"2026-12-30",{"name":5,"class":6},1]