[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100524047":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":27,"centralContacts":32,"locations":42,"responsibleParty":59,"collaborators":24,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":24,"eligibilityCriteria":67,"healthyVolunteers":63,"sex":68,"minAge":69,"maxAge":24,"enrollmentInfo":70,"targetDuration":24,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":79,"overallStatus":45,"whyStopped":24,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"National Cheng-Kung University Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Control group","SHAM_COMPARATOR","Mandibular advancement device",[13],"Other: Mandibular advancement device",{"label":15,"type":16,"description":17,"interventionNames":18},"Intervention group","EXPERIMENTAL","Participants will received 1-2 times a week, 12-week-intervention of Oropharyngeal Exercises and Mandibular advancement device.",[19,13],"Other: Oropharyngeal Exercises",[21,25],{"type":6,"name":22,"description":22,"armGroupLabels":23,"otherNames":24},"Oropharyngeal Exercises",[15],null,{"type":6,"name":11,"description":11,"armGroupLabels":26,"otherNames":24},[9,15],[28],{"name":29,"affiliation":30,"role":31},"Ching-Hsia Hung, PhD","National Cheng Kung University","PRINCIPAL_INVESTIGATOR",[33,38],{"name":34,"role":35,"phone":36,"phoneExt":24,"email":37},"Man-Hui Chooi, MS","CONTACT","+886-9-23127284","amymanhui@gmail.com",{"name":29,"role":35,"phone":39,"phoneExt":40,"email":41},"+886-6-2353535","5939","chhung@mail.ncku.edu.tw",[43],{"facility":44,"status":45,"city":46,"state":24,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"National Cheng Kung University Hospital","RECRUITING","Tainan","704","Taiwan","TW",{"type":51,"coordinates":52},"Point",[53,54],120.21333,22.99083,{"lat":54,"lon":53},[57],{"name":29,"role":35,"phone":58,"phoneExt":40,"email":41},"06-2353535",{"type":60,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR","100524047","efficacy-of-oropharyngeal-exercises-for-patients-with-obstructive-sleep-apnea-using-mandibular-advancement-device-100524047",false,"NCT06103630","Efficacy of Oropharyngeal Exercises for Patients With Obstructive Sleep Apnea Using Mandibular Advancement Device","Efficacy of Oropharyngeal Exercises for Patients With Residual Obstructive Sleep Apnea Using Mandibular Advancement Device","Inclusion Criteria:\n\n* OSA patients\n* Aged over 20 years\n* Wearing MAD (The amount of MAD is at least 50% of the maximum amount that the patient can achieve.)\n\nExclusion Criteria:\n\n* Body Mass Index (BMI) ≧ 35\n* Pregnancy\n* Severe obstructive or restrictive lung disease\n* Exercise with high-risk cardiovascular disease\n* History of central or peripheral neurological disease resulting in an inability to perform exercise prescriptions\n* Musculoskeletal or psychological disorders that prevent the performance of exercise prescriptions\n* Chronic illnesses that are ongoing or not yet controlled","ALL","20 Years",{"count":71,"type":72},20,"ESTIMATED","INTERVENTIONAL",[75],"NA","Oropharyngeal muscle training has emerged as a novel adjunctive treatment approach, involving training of the swallowing muscle group and tongue muscles to prevent tongue collapse, reduce tongue base volume during sleep, and strengthen muscle tension.\n\nTherefore, the objective is to assess changes in oropharyngeal muscle strength, ultrasonographic tongue morphology, severity of sleep related breathing interruptions, clinical symptoms, and correlations among these factors. Oropharyngeal muscle training for patients with residual OSA using MAD can significantly 1. increase muscle strength and endurance. 2. reduce the severity of sleep-related breathing interruptions. 3. decrease clinical symptoms. 4. improve tongue morphology.",[78],"Obstructive Sleep Apnea of Adult",[80,81,82],"Obstructive Sleep Apnea","Mandibular Advancement Device therapy","Oropharyngeal muscle training","2024-03-20",{"date":85,"type":86},"2024-03-21","ACTUAL",{"date":88,"type":86},"2023-11-02",{"date":90,"type":72},"2027-12-31",{"name":5,"class":6},1]