[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100630163":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":29,"locations":38,"responsibleParty":64,"collaborators":66,"id":69,"slug":70,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":75,"eligibilityCriteria":76,"healthyVolunteers":71,"sex":77,"minAge":78,"maxAge":25,"enrollmentInfo":79,"targetDuration":25,"studyType":82,"phases":83,"briefSummary":85,"conditions":86,"keywords":90,"overallStatus":95,"whyStopped":25,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":105},{"fullName":5,"class":6},"Tampere University Hospital","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Proximal median nerve release","EXPERIMENTAL","Operative treatment: proximal median nerve release",[13,14],"Procedure: Proximal median nerve release","Other: Physiotherapy",{"label":16,"type":17,"description":18,"interventionNames":19},"Physiotherapy","ACTIVE_COMPARATOR","Conservative treatment: physiotherapy",[14],[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Participants randomized to operative treatment will be scheduled for surgery. During surgery, the proximal median nerve compression will be released in a manner deemed best by the treating surgeon. Patients randomized to surgery will also receive conservative management following surgery.",[9],null,{"type":6,"name":16,"description":27,"armGroupLabels":28,"otherNames":25},"Participants randomized to conservative treatment will receive information about median nerve compression and written instructions for self-directed nerve stretching exercises. There will be one supervision visit with a physiotherapist at the beginning of the treatment period.",[16,9],[30,35],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},"Jarkko Jokihaara","CONTACT","+3583311611","jarkko.jokihaara@pirha.fi",{"name":36,"role":32,"phone":33,"phoneExt":25,"email":37},"Henrikki Rönkkö","henrikki.ronkko@pirha.fi",[39,55],{"facility":40,"status":25,"city":41,"state":25,"zip":25,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Seinäjoki Central Hospital","Seinäjoki","Finland","FI",{"type":45,"coordinates":46},"Point",[47,48],22.82822,62.79446,{"lat":48,"lon":47},[51],{"name":52,"role":32,"phone":53,"phoneExt":25,"email":54},"Pekka Löppönen","+3586 4154111","pekka.lopponen@hyvaep.fi",{"facility":5,"status":25,"city":56,"state":25,"zip":25,"country":42,"countryCode":43,"cosmosGeoPoint":57,"geoPoint":61,"contacts":62},"Tampere",{"type":45,"coordinates":58},[59,60],23.78712,61.49911,{"lat":60,"lon":59},[63],{"name":36,"role":32,"phone":33,"phoneExt":25,"email":37},{"type":65,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR",[67],{"name":68,"class":6},"Seinajoki Central Hospital","100630163","efficacy-of-proximal-median-nerve-release-100630163",false,"NCT07484100","Efficacy of Proximal Median Nerve Release","Efficacy of Operative Versus Conservative Treatment in Proximal Median Nerve Compression","PROMER","Inclusion Criteria:\n\n1. Clinically diagnosed PMNC\n2. If the patient has clinically and electrodiagnostically confirmed carpal tunnel syndrome, at least 6 months must have passed since surgical treatment\n3. Age 18 or over\n4. Ability to understand Finnish\n5. Ability to complete electronic questionnaires independently\n6. Willingness to participate in research and follow research instructions\n7. Provision of informed consent from the participant\n\nExclusion Criteria:\n\n1. Nerve root disorder findings in ENMG\n2. Thoracic outlet syndrome, TOS\n3. Other neurological condition that causes upper limb symptoms such as MS, previous nerve injury\n4. Active rheumatoid arthritis or any other active inflammatory joint disease that affects hand function\n5. Significant compression symptoms of another peripheral nerve in association with PMNC\n6. Other upper extremity operation performed less than 6 months ago\n7. Another disease or condition that accounts for most of the patient's symptoms\n8. Other known reasons that may prevent participation or implementation of treatment during the study","ALL","18 Years",{"count":80,"type":81},160,"ESTIMATED","INTERVENTIONAL",[84],"NA","A multi-center randomized controlled clinical trial which determines the efficacy of proximal median nerve release in patients with persistent proximal median nerve compression. The primary outcome is patient reported improvement of symptoms on a 7-point Likert scale at 6 months after the randomization to treatment group.",[87,88,89],"Carpal Tunnel Surgery","Median Nerve Compression","Median Nerve Entrapment",[91,92,93,94],"proximal median nerve entrapment","proximal median nerve compression","proximal median nerve release","randomized controlled trial","NOT_YET_RECRUITING","2026-03-17",{"date":98,"type":99},"2026-03-19","ACTUAL",{"date":101,"type":81},"2026-03-01",{"date":103,"type":81},"2041-07",{"name":5,"class":6},2]