[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100553690":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":29,"locations":35,"responsibleParty":51,"collaborators":25,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":57,"acronym":25,"eligibilityCriteria":58,"healthyVolunteers":55,"sex":59,"minAge":60,"maxAge":25,"enrollmentInfo":61,"targetDuration":25,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":71,"overallStatus":74,"whyStopped":25,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Zhongnan Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Ho: YAG lithotripsy","ACTIVE_COMPARATOR","Ho; YAG laser therapy device is used. The patient adopts lithotomy position. After general anesthesia, a semi-rigid ureteroscope is used to enter the bladder through the urethra to observe the ureteral opening, and then a hydrophilic guide wire is inserted into the ureter on the affected side. After the semi-rigid ureteroscope slowly enters along the hydrophilic guide wire and reaches the bottom of the stone, the laser optical fiber of the laser therapy device is inserted into the working channel of the ureteroscope so that the end of the optical fiber is exposed in the field of view of the ureteroscope. After the laser therapy device sets the lithotripsy parameters, the optical fiber is aimed at the stone for laser lithotripsy.",[13],"Device: Ho: YAG lithotripsy",{"label":15,"type":16,"description":17,"interventionNames":18},"Thulium Fiber laser (TFL) lithotripsy","EXPERIMENTAL","The patient adopts lithotomy position. After general anesthesia, a semi-rigid ureteroscope is used to enter the bladder through the urethra to observe the ureteral opening, and then a hydrophilic guide wire is inserted into the ureter on the affected side. After the semi-rigid ureteroscope slowly enters along the hydrophilic guide wire and reaches the bottom of the stone, the laser fiber of the laser therapy machine is inserted into the working channel of the ureteroscope so that the end of the fiber is exposed to the field of view of the ureteroscope. Using the TFL laser therapy device, after setting the lithotripsy parameters, the fiber is aimed at the stone for laser lithotripsy.",[19],"Device: Thulium Fiber laser (TFL) lithotripsy",[21,26],{"type":22,"name":15,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","Patients with proximal ureteral stones undergoing ureteroscopic lithotripsy using thulium laser lithotripsy.",[15],null,{"type":22,"name":9,"description":27,"armGroupLabels":28,"otherNames":25},"Ho:YAG laser lithotripsy was used in patients with proximal ureteral stones undergoing ureteroscopic lithotripsy.",[9],[30],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},"Xinghuan Wang","CONTACT","+86 18770426026","wangxinghuan@whu.edu.cn",[36],{"facility":37,"status":25,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Zhongnan Hospital, Wuhan University,","Wuhan","Hubei","430071","China","CN",{"type":44,"coordinates":45},"Point",[46,47],114.26667,30.58333,{"lat":47,"lon":46},[50],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},{"type":52,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100553690","efficacy-of-semi-rigid-ureteroscopic-laser-lithotripsy-in-the-treatment-of-proximal-ureteral-stones-a-randomized-controlled-trial-100553690",false,"NCT06489366","Efficacy of Semi-rigid Ureteroscopic Laser Lithotripsy in the Treatment of Proximal Ureteral Stones: a Randomized Controlled Trial","Inclusion Criteria:\n\n1. ≥18 years old;\n2. patients diagnosed with unilateral proximal ureteral stones ≤2cm by computed tomography (CT)\u002FKidney and upper bladder (KUB) radiography who required surgery;\n3. patients who volunteered to participate in this study.\n\nExclusion Criteria:\n\n1. Unable to give informed consent;\n2. Untreated urinary tract infection;\n3. Pregnant women;\n4. Known anatomical abnormalities (such as urinary diversion or ureteral stenosis);\n5. Urothelial tumors, transplanted kidney stones, irreversible coagulopathy;\n6. The semi-rigid ureteroscope cannot reach the stone site, ureteroscopy-negative stones, and stones can be removed directly without laser lithotripsy;\n7. The researchers believe that they are not suitable for participation in this study.","ALL","18 Years",{"count":62,"type":63},138,"ESTIMATED","INTERVENTIONAL",[66],"NA","The efficacy of Ho: YAG and TFL combined with semirigid ureteroscopic treatment of proximal ureteral stones will be compared.",[69,70],"Urolithiasis","Proximal Ureteral Stone",[72,9,15,73],"Proximal ureteral stones","Semirigid ureteroscopic lithotripsy","NOT_YET_RECRUITING","2024-06-28",{"date":77,"type":78},"2024-07-05","ACTUAL",{"date":80,"type":63},"2024-06-26",{"date":82,"type":63},"2025-02-26",{"name":5,"class":6},1]