[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100600243":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":26,"responsibleParty":37,"collaborators":26,"id":40,"slug":41,"hasResults":42,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":26,"eligibilityCriteria":46,"healthyVolunteers":42,"sex":47,"minAge":48,"maxAge":49,"enrollmentInfo":50,"targetDuration":26,"studyType":53,"phases":54,"briefSummary":56,"conditions":57,"keywords":26,"overallStatus":60,"whyStopped":26,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":26},{"fullName":5,"class":6},"Seoul National University Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"SVF-treated side","EXPERIMENTAL","Intradermal injection of autologous stromal vascular fraction (SVF) on one side of the face.",[13],"Biological: stromal vascular fraction (SVF)",{"label":15,"type":16,"description":17,"interventionNames":18},"Saline-treated side","PLACEBO_COMPARATOR","Intradermal injection of normal saline (NS) on the contralateral side of the face.",[19],"Other: Normal Saline (NS)",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BIOLOGICAL","stromal vascular fraction (SVF)","Autologous stromal vascular fraction (SVF) isolated from adipose tissue was injected intradermally into one side of the face to evaluate its efficacy in treating atrophic acne scars. SVF was freshly prepared on the same day of injection using enzymatic digestion and centrifugation.",[9],null,{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Normal Saline (NS)","Normal saline (NS) was injected intradermally into the contralateral side of the face and served as a placebo comparator to SVF in this split-face study on atrophic acne scars.",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Dae Hun Suh","CONTACT","82+2-2072-2714","daehun@snu.ac.kr",{"type":38,"investigatorFullName":33,"investigatorTitle":39,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Professor","100600243","efficacy-of-stromal-vascular-fraction-on-acne-scar-correction-100600243",false,"NCT07094958","Efficacy of Stromal Vascular Fraction on Acne Scar Correction","Efficacy of Intradermal Stromal Vascular Fraction Injection in the Treatment of Atrophic Acne Scar","Inclusion Criteria:\n\n* Age between 19 and 45 years\n* Presence of bilateral atrophic acne scars (boxcar, rolling, or icepick types) on the face\n* Willingness to undergo fat harvesting procedure\n* Ability to comply with study visits and follow-up\n* Written informed consent obtained\n\nExclusion Criteria:\n\n* Active acne lesions on the treatment area\n* History of keloid or hypertrophic scarring\n* Prior treatment for acne scars (e.g., laser, filler, microneedling) within the past 6 months\n* History of systemic immunosuppressive therapy within the past 3 months\n* Pregnant or breastfeeding women\n* Any systemic disease that may interfere with wound healing or safety assessment (e.g., uncontrolled diabetes, collagen vascular disease)","ALL","19 Years","45 Years",{"count":51,"type":52},16,"ESTIMATED","INTERVENTIONAL",[55],"NA","This study aims to evaluate the efficacy and safety of intradermal injection of autologous stromal vascular fraction (SVF) in the treatment of atrophic acne scars. SVF is a heterogeneous cell population derived from adipose tissue, containing various regenerative and immunomodulatory cells, including mesenchymal stem cells, endothelial progenitor cells, and pericytes.\n\nIn this prospective, randomized, split-face clinical trial, participants with atrophic acne scars will receive SVF injections on one side of the face and normal saline (NS) injections on the contralateral side as a control. Clinical efficacy will be assessed through blinded scar counts, digital imaging, and histological evaluations including epidermal and dermal regenerative markers. The study is designed to investigate whether SVF provides superior clinical improvement compared to placebo.",[58,59],"Acne Scars","Acne Scars - Atrophic","NOT_YET_RECRUITING","2025-07-29",{"date":63,"type":64},"2025-07-31","ACTUAL",{"date":66,"type":52},"2025-07",{"date":68,"type":52},"2026-07",{"name":5,"class":6}]