[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100643353":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":30,"locations":38,"responsibleParty":54,"collaborators":20,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":60,"acronym":20,"eligibilityCriteria":61,"healthyVolunteers":58,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":20,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":77,"overallStatus":41,"whyStopped":20,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"Marmara University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients with ankylosing spondylitis and resistant persistent back pain who underwent erector spinae","ACTIVE_COMPARATOR","Patients with ankylosing spondylitis whose disease activity is adequately controlled under medical treatment but who are referred due to persistent back pain will undergo erector spinae plane block. All assessments, including pain severity, disease activity, general functional status, and spinal mobility, will be performed at baseline (T0), 2 weeks after the procedure (T1), and 2 months after the procedure (T2).",[13],"Procedure: Erector spinae plane block(ESBP)",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"PROCEDURE","Erector spinae plane block(ESBP)","The procedure will be performed in the prone position under sterile conditions and ultrasound guidance. Using a 22-gauge needle at the T5-T7 vertebral levels, the fascial plane between the deep fascia of the erector spinae muscle group and the transverse process of the vertebra will be accessed. A combination consisting of 5 cc of 0.5% bupivacaine, 4 cc of 0.9% normal saline, and 1 cc dexamethasone (8 mg\u002F2 mL) will then be injected into the targeted plane.\n\nThe procedure will be performed by experienced algology specialists with more than 15 years of experience in ultrasound-guided interventional procedures and will be administered in two sessions within one week.",[9],null,[22,26],{"name":23,"affiliation":24,"role":25},"Fatma B Akdağ, Research Assistant","Marmara University Faculty of Medicine ,Marmara University, Department of Physical Medicine and Rehabilitation","PRINCIPAL_INVESTIGATOR",{"name":27,"affiliation":28,"role":29},"Savaş Şencan, Associate Professor","Algology Division, Department of Physical Medicine and Rehabilitation, Marmara University Faculty of Medicine","STUDY_DIRECTOR",[31,35],{"name":23,"role":32,"phone":33,"phoneExt":20,"email":34},"CONTACT","+90 537 452 96 60","fatma.betul820@gmail.com",{"name":27,"role":32,"phone":36,"phoneExt":20,"email":37},"+90 537 066 57 13","savas-44@hotmail.com",[39],{"facility":40,"status":41,"city":42,"state":43,"zip":20,"country":44,"countryCode":20,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Marmara University Faculty of Medicine Pendik Training and Research Hospital","RECRUITING","Istanbul","Pendik","Turkey (Türkiye)",{"type":46,"coordinates":47},"Point",[48,49],28.94966,41.01384,{"lat":49,"lon":48},[52],{"name":23,"role":32,"phone":53,"phoneExt":20,"email":34},"+905374529660",{"type":55,"investigatorFullName":20,"investigatorTitle":20,"investigatorAffiliation":20,"oldNameTitle":20,"oldOrganization":20},"SPONSOR","100643353","efficacy-of-the-erector-spinae-plane-block-for-persistent-back-pain-in-patients-with-ankylosing-spondylitis-100643353",false,"NCT07633730","Efficacy of the Erector Spinae Plane Block for Persistent Back Pain in Patients With Ankylosing Spondylitis","Inclusion Criteria:\n\n* Age between 18 and 65 years\n* Diagnosis of ankylosing spondylitis according to the Modified New York Criteria\n* Patients receiving ongoing treatment with controlled disease activity but persistent back pain\n* Willingness to participate in the study\n\nExclusion Criteria:\n\n* Body mass index (BMI) greater than 35 kg\u002Fm²\n* History of thoracic surgery\n* Intellectual disability or mental retardation\n* Presence of major psychiatric comorbidity\n* Congenital spinal anomaly\n* Pregnancy\n* History of bleeding diathesis\n* Presence of active local and\u002For systemic infection\n* Known allergy to the medications to be injected\n* Hemodynamic instability\n* Active phase of the disease (elevated acute phase reactants, active arthritis findings, etc.)","ALL","18 Years","65 Years",{"count":66,"type":67},15,"ESTIMATED","INTERVENTIONAL",[70],"NA","Despite adequate control of disease activity with standard medical therapies, there remains an ongoing need for complementary and interventional approaches for the management of persistent back pain in patients with ankylosing spondylitis. Although the erector spinae plane block has been described in the literature as a safe and effective analgesic intervention for chronic back pain in various patient populations, to the best of our knowledge, no clinical study has specifically evaluated its use for persistent back pain in patients with ankylosing spondylitis receiving medical treatment. Therefore, the present study aims to evaluate the effects of erector spinae plane block on pain severity and clinical outcomes in patients with ankylosing spondylitis whose disease activity is controlled under treatment but who continue to experience persistent back pain.",[73,74,75,76],"Ankylosing Spondylitis (AS)","Back Pain","ESPB","Regional Anesthesia",[75,78,74,79,80,81],"Erector Spinae Plane Block","Ankylosing Spondylitis","Persistent back pain","Regional anesthesia","2026-06-02",{"date":84,"type":85},"2026-06-08","ACTUAL",{"date":82,"type":85},{"date":88,"type":67},"2027-06-02",{"name":5,"class":6},1]