[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100455238":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":33,"centralContacts":37,"locations":42,"responsibleParty":62,"collaborators":24,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":24,"eligibilityCriteria":71,"healthyVolunteers":67,"sex":72,"minAge":73,"maxAge":24,"enrollmentInfo":74,"targetDuration":24,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":83,"overallStatus":44,"whyStopped":24,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"University of Las Palmas de Gran Canaria","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Non-invasive Neuromodulation","EXPERIMENTAL","Intervention with microcurrents: application of 6 electrodes per extremity and an adhesive electrode at C7 level and and in the popliteal fossa.",[13],"Device: Non-invasive Neuromodulation",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo Non-invasive Neuromodulation","SHAM_COMPARATOR","Placebo microcurrents Intervention with microcurrents: application of 6 electrodes per extremity and an adhesive electrode at C7 level and in the popliteal fossa.",[19],"Device: Placebo Non-invasive Neuromodulation",{"label":21,"type":22,"description":23,"interventionNames":24},"Control","NO_INTERVENTION","Participant will maintain the conventional rehabilitation treatment",null,[26,30],{"type":27,"name":9,"description":28,"armGroupLabels":29,"otherNames":24},"DEVICE","The electrodes will be placed with the help of gloves and adapted socks for 1 hour, twice a week, until 10 intervention sessions are completed. In addition, depending on the session, an adhesive electrode will be placed at the level of C7. Characteristics of microcurrents: pulsed monophasic rectangular wave with a pulse of 1.3 s and pause of 300 ms, voltage 3 millivolt and intensity 0.5 μA.",[9],{"type":27,"name":15,"description":31,"armGroupLabels":32,"otherNames":24},"The same protocol described for the experimental group will be applied, but microcurrents device which will be previously manipulated and tested with an oscilloscope so that they do not emit electrical currents",[15],[34],{"name":35,"affiliation":5,"role":36},"Aníbal Báez Suárez, PhD","PRINCIPAL_INVESTIGATOR",[38],{"name":35,"role":39,"phone":40,"phoneExt":24,"email":41},"CONTACT","652077692","anibal.baez@ulpgc.es",[43],{"facility":5,"status":44,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"RECRUITING","Las Palmas de Gran Canaria","Las Palmas","35016","Spain","ES",{"type":51,"coordinates":52},"Point",[53,54],-15.41573,28.10178,{"lat":54,"lon":53},[57,60],{"name":58,"role":39,"phone":59,"phoneExt":24,"email":41},"Anibal Báez, Professor","+34652077692",{"name":61,"role":36,"phone":24,"phoneExt":24,"email":24},"Aníbal Báez Suárez, Professor",{"type":36,"investigatorFullName":63,"investigatorTitle":64,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"Aníbal Báez Suárez","Principal Investigator","100455238","efficacy-of-the-nxsignal-device-for-the-treatment-of-anterior-cruciate-ligament-injuries-100455238",false,"NCT05207943","Efficacy of the NXSignal Device for the Treatment of Anterior Cruciate Ligament Injuries","Efficacy of the NXSignal Device for the Treatment of Anterior Cruciate Ligament Injuries. Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* Over 16 years old\n* In normal conditions and mentally competent to participate in the study.\n* Not having previous knee surgeries.\n* In condition to complete the study questionnaires.\n\nExclusion Criteria:\n\n* Present some of the contraindications for a treatment with NESA XSIGNAL®: pacemakers, internal bleeding, do not apply electrodes on skin in poor condition, with ulcerations or wounds, acute febrile processes, acute thrombophlebitis and \u002F or electricity phobia.\n* Not having signed the informed consent.\n* Urgent surgical interventions.","ALL","16 Years",{"count":75,"type":76},40,"ESTIMATED","INTERVENTIONAL",[79],"NA","Injury to the anterior cruciate ligament (ACL) is very common among sports professionals and the general population \\[. Unlike other joint injuries, it is reversible, but it can damage adjacent tissues, particularly the meniscus, and catalyze knee osteoarthritis.\n\nACL injury produces instability, joint mechanical alteration, which can lead to degenerative joint diseases. The goal of treating the injury will be to prevent symptomatic instability, restore normal knee kinematics, and prevent degenerative joint disease .\n\nIts usual treatment is surgical and therefore contributes to a significant cost for the health system, both for the surgeries themselves, and for the rehabilitation and subsequent recovery processes.\n\nWithin recovery therapies, in some cases, and given their popularity within the world of physiotherapy, electrotherapy techniques are proposed, primarily transcutaneous electrical nerve stimulation-type techniques with action on the muscular system and analgesia.\n\nAn early intervention with neuromuscular electrostimulation electrotherapy (NMES) combined with repeated exercises is effective for the recovery of strength and restoration of the biomechanical symmetry of the limb.\n\nThere is a diversity of opinions and disparate results regarding the use of this type of technique , in any case, it has been shown that electrical stimulation favors cell migration and joint tissue regeneration.",[82],"Anterior Cruciate Ligament Injuries",[84,85,86],"physical therapy modality","Electric Stimulation Therapy","Anterior Cruciate Ligament","2025-08-21",{"date":89,"type":90},"2025-08-28","ACTUAL",{"date":92,"type":90},"2021-05-25",{"date":94,"type":76},"2025-12-25",{"name":5,"class":6},1]