[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100636021":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":29,"locations":38,"responsibleParty":55,"collaborators":12,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":12,"eligibilityCriteria":65,"healthyVolunteers":61,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":12,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":80,"overallStatus":40,"whyStopped":12,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Bangladesh Medical University","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Control Group: Conventional Pain Management","NO_INTERVENTION","This group will receive general anesthesia along with conventional pain management techniques, including opioid analgesics and other standard interventions typically used in postoperative nephrectomy care",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Intervention Group: Ultrasound-Guided Erector Spinae Plane Block","EXPERIMENTAL","Patients in this group will receive general anesthesia in combination with the ultrasound-guided erector spinae plane (ESP) block, administered before the induction of anesthesia. The block targets the erector spinae muscle fascial plane, aiming to reduce postoperative pain and opioid consumption.",[18],"Procedure: Ultrasound-Guided Erector Spinae Plane (ESP) Block",[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":12},"PROCEDURE","Ultrasound-Guided Erector Spinae Plane (ESP) Block","The Ultrasound-Guided Erector Spinae Plane (ESP) Block is a regional anesthesia technique used to provide postoperative pain relief. In this study, the intervention involves the administration of a local anesthetic (0.25% bupivacaine) into the fascial plane between the erector spinae muscle and the transverse process of the vertebra using ultrasound guidance. The procedure is performed immediately before the induction of general anesthesia in patients undergoing open nephrectomy. The goal of the ESP block is to reduce postoperative pain, minimize opioid consumption, and improve recovery outcomes while maintaining hemodynamic stability. This intervention is compared to conventional pain management methods, which primarily rely on systemic opioids and other standard analgesics.",[14],[26],{"name":27,"affiliation":5,"role":28},"AKM Akhtaruzzaman, MD","STUDY_DIRECTOR",[30,35],{"name":31,"role":32,"phone":33,"phoneExt":12,"email":34},"Kazi Mahzabin Arin, MD","CONTACT","+8801754057689","kazimahzabinarin@bsmmu.edu.bd",{"name":27,"role":32,"phone":36,"phoneExt":12,"email":37},"+8801819220195","akm.akhtaruzzaman@bmu.ac.bd",[39],{"facility":5,"status":40,"city":41,"state":12,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"RECRUITING","Dhaka","1000","Bangladesh","BD",{"type":46,"coordinates":47},"Point",[48,49],90.40744,23.7104,{"lat":49,"lon":48},[52,54],{"name":53,"role":32,"phone":36,"phoneExt":12,"email":37},"AKM Mahzabin Akhtaruzzaman, MD",{"name":31,"role":32,"phone":33,"phoneExt":12,"email":34},{"type":56,"investigatorFullName":57,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":12,"oldOrganization":12},"PRINCIPAL_INVESTIGATOR","Kazi Mahzabin Arin","Assistant Professor","100636021","efficacy-of-ultrasound-guided-erector-spinae-block-for-postoperative-pain-management-in-nephrectomy-100636021",false,"NCT07560267","Efficacy of Ultrasound-Guided Erector Spinae Block for Postoperative Pain Management in Nephrectomy","Efficacy of Ultrasound-Guided Erector Spinae Plane Block in Postoperative Pain Management in Nephrectomy: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Adult patients aged 18 to 64 years\n* Scheduled for open nephrectomy (radical or partial) under general anesthesia\n* ASA physical status I-II (American Society of Anesthesiologists classification)\n\nExclusion Criteria:\n\n* Allergy to local anesthetics.\n* Local infection or inflammation at the site of the Block placement.\n* Presence of anatomical deformities in the spine\n* Coagulopathy or any bleeding disorder.\n* Pregnancy or breastfeeding women.\n* History of severe chronic pain syndrome","ALL","18 Years","64 Years",{"count":70,"type":71},66,"ESTIMATED","INTERVENTIONAL",[74],"NA","This clinical trial aims to evaluate the effectiveness of the ultrasound-guided erector spinae plane (ESP) block in managing postoperative pain for patients undergoing open nephrectomy (kidney removal surgery). The study will compare this new technique to traditional pain management methods, such as opioid medications, to assess whether the ESP block reduces pain and the need for opioids after surgery.\n\nPatients will be randomly assigned to one of two groups:\n\nGroup C will receive conventional pain relief methods, including opioids. Group E will receive the ultrasound-guided ESP block in addition to general anesthesia.\n\nThe main goals are to determine:\n\nHow much pain relief each method provides, measured using a visual analog scale (VAS).\n\nThe total amount of opioids required during the first 24 hours post-surgery.\n\nAdditional measurements will include monitoring vital signs like heart rate, blood pressure, and oxygen levels.\n\nThis study will help find safer and more effective ways to manage pain after nephrectomy, reducing the reliance on opioids and improving patient recovery",[77,78,79],"Erector Spinae Plane Block","Nephrectomy","Postoperative Pain",[81,82,83,78],"Erector Spinae Plane Block (ESP)","Postoperative Pain Management","Opioid Consumption","2026-04-24",{"date":86,"type":87},"2026-05-01","ACTUAL",{"date":89,"type":87},"2025-09-01",{"date":91,"type":71},"2026-07-30",{"name":5,"class":6},1]