[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100600371":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":35,"locations":42,"responsibleParty":77,"collaborators":18,"id":80,"slug":81,"hasResults":82,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":18,"eligibilityCriteria":86,"healthyVolunteers":82,"sex":87,"minAge":88,"maxAge":89,"enrollmentInfo":90,"targetDuration":18,"studyType":93,"phases":94,"briefSummary":96,"conditions":97,"keywords":18,"overallStatus":44,"whyStopped":18,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":109},{"fullName":5,"class":6},"Zhongshan Ophthalmic Center, Sun Yat-sen University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"intervention group","EXPERIMENTAL","Participants in the intervention group will undergo refraction at baseline and be prescribed appropriately powered spectacles based on the refraction results, which they will wear full-time. Following instruction from a trainer, they will receive training via the online platform of the visual perceptual training therapy software (HVT, Version: V1.0.10000) for 30 minutes daily for a total duration of 3 months. Follow-up visits and ophthalmic examinations will be conducted at 1, 2, and 3 months after trial initiation.",[13],"Device: perceptual learning visual treatment,HVT",{"label":15,"type":16,"description":17,"interventionNames":18},"compare group","NO_INTERVENTION","Participants in the control group will undergo refraction at baseline and be prescribed appropriately powered spectacles based on the refraction results, which they will wear full-time. They will receive occlusion therapy in accordance with the Amblyopia Preferred Practice Pattern (2024) issued by the American Academy of Ophthalmology for a total duration of 3 months. Follow-up visits and ophthalmic examinations will be conducted at 1, 2, and 3 months after trial initiation.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"DEVICE","perceptual learning visual treatment,HVT","After receiving guidance from a trainer, treatment was conducted using the visual perception training therapy software (HVT, version number: V1.0.10000) on a network platform for 30 minutes per day, totaling 3 months.",[9],[26,30,33],{"name":27,"affiliation":28,"role":29},"Guangming Jin, M.D.","Guangdong Provincial Clinical Research Center for Ocular Diseases, State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, Guangdong","PRINCIPAL_INVESTIGATOR",{"name":31,"affiliation":28,"role":32},"Zhenzhen Liu, M.D.","STUDY_CHAIR",{"name":34,"affiliation":28,"role":32},"Danying Zheng, M.D.",[36],{"name":37,"role":38,"phone":39,"phoneExt":40,"email":41},"Guangming Jin, Ph.D.","CONTACT","+86 02066604125","13560035613","jinguangming@gzzoc.com",[43,62],{"facility":28,"status":44,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"RECRUITING","Guangzhou","Guangdong","510060","China","CN",{"type":51,"coordinates":52},"Point",[53,54],113.25,23.11667,{"lat":54,"lon":53},[57,61],{"name":58,"role":38,"phone":59,"phoneExt":18,"email":60},"Haotian Lin, M.D.","+86 020-66607666","gddlht@aliyun.com",{"name":27,"role":29,"phone":18,"phoneExt":18,"email":18},{"facility":63,"status":64,"city":65,"state":46,"zip":66,"country":48,"countryCode":49,"cosmosGeoPoint":67,"geoPoint":71,"contacts":72},"Qingyuan Hospital Affiliated to Guangzhou Medical University (Qingyuan People's Hospital)","NOT_YET_RECRUITING","Qingyuan","511500",{"type":51,"coordinates":68},[69,70],113.03333,23.7,{"lat":70,"lon":69},[73],{"name":74,"role":38,"phone":75,"phoneExt":18,"email":76},"Tingting Yang","13620507831","qyrykyb@163.com",{"type":29,"investigatorFullName":78,"investigatorTitle":79,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Guangming Jin","Associate Chief Physician, Cataract Department","100600371","efficacy-of-visual-and-perceptual-training-on-visual-function-for-operative-congenital-ectopia-lentis-children-100600371",false,"NCT07096622","Efficacy of Visual and Perceptual Training on Visual Function for Operative Congenital Ectopia Lentis Children","Efficacy of Visual and Perceptual Training on Visual Function for Operative Congenital Ectopia Lentis Children: A Randomized Controlled Clinical Trial","Inclusion Criteria\n\n1. Aged 4-12 years, with no gender restriction;\n2. Diagnosed with congenital ectopia lentis;\n3. Underwent bilateral lensectomy combined with IOL scleral fixation, and within 1 month ± 1 week after the second-eye surgery;\n4. Best-corrected visual acuity (BCVA) of unilateral or bilateral eyes is no worse than 20\u002F200 but below the normal level for the corresponding age: for 4-year-old children, BCVA ≤ 20\u002F40; for children aged 5 years and above, BCVA ≤ 20\u002F30;\n5. Written informed consent signed by the patient and their parents or legal guardians.\n\nExclusion Criteria\n\n1. History of ocular trauma or previous ocular surgery other than the study-related procedure;\n2. Unable to cooperate with treatment, examinations, and follow-up assessments;\n3. Complicated with recurrent lens dislocation, severe cataract (dense, axial, opacity diameter \\>3 mm and affecting central vision), secondary glaucoma, corneal endothelial decompensation, retinal detachment, or other conditions requiring urgent surgical intervention;\n4. Presence of diplopia in either eye;\n5. Known history of neurological disorders (e.g., photosensitive epilepsy);\n6. Participation in other clinical trials within the postoperative period that may affect the outcomes of the present study;\n7. Use of topical or systemic medications that may cause visual impairment, or other vision therapies other than refractive correction in the past 3 months (e.g., atropine penalization, occlusion therapy, digital therapy, Bangerter filters, optical suppression, VR training, etc.).","ALL","4 Years","12 Years",{"count":91,"type":92},82,"ESTIMATED","INTERVENTIONAL",[95],"NA","This is a multi-centre, open-label, parallel-group randomized controlled trial with the following objectives: Firstly, the investigators aim to evaluate the efficacy of web-based visual and perceptual training therapy on visual function in children with postoperative congenital ectopia lentis. Secondly, the investigators target to investigate the in stereoacuity, quality of life scores, and treatment compliance following visual and perceptual training intervention. Thirdly, to explore the safety profile of visual and perceptual training therapy software in this specific patient population. Lastly, this study aims to provide evidence-based recommendations for visual rehabilitation training strategies in children with postoperative congenital ectopia lentis in the Chinese population.",[98,99],"Ectopia Lentis","Lens Subluxation or Dislocation","2026-04-21",{"date":102,"type":103},"2026-04-27","ACTUAL",{"date":105,"type":92},"2026-06-01",{"date":107,"type":92},"2029-06-30",{"name":5,"class":6},2]