[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100623289":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":30,"locations":25,"responsibleParty":36,"collaborators":25,"id":40,"slug":41,"hasResults":42,"nctId":43,"briefTitle":44,"officialTitle":44,"acronym":25,"eligibilityCriteria":45,"healthyVolunteers":42,"sex":46,"minAge":47,"maxAge":48,"enrollmentInfo":49,"targetDuration":25,"studyType":52,"phases":53,"briefSummary":55,"conditions":56,"keywords":25,"overallStatus":58,"whyStopped":25,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":25},{"fullName":5,"class":6},"Capital Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"IH group","ACTIVE_COMPARATOR","Participants will receive 10 times intermittent hypoxia (oxygen concentration: 13%) intervention.",[13],"Other: Intermittent Hypoxia",{"label":15,"type":16,"description":17,"interventionNames":18},"Control group","SHAM_COMPARATOR","Participants will receive 10 times sham-hypoxia (oxygen concentration: 21%) intervention in 5 days.",[19],"Other: Sham Intermittent Hypoxia",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Intermittent Hypoxia","The intermittent hypoxia protocol refers to four cycles of 5 minutes hypoxia inhaling interval by 5 minutes normoxia, which is performed twice a day (at least 6 hours apart) in 7 days.",[9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Sham Intermittent Hypoxia","The sham intermittent hypoxia protocol refers to 45 minutes normoxia inhaling, which is performed twice a day (at least 6 hours apart) in 7 days.",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Yuan Wang","CONTACT","+86-13581567815","wilma0106@163.com",{"type":37,"investigatorFullName":38,"investigatorTitle":39,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Ji Xunming,MD,PhD","Principal Investigator","100623289","efficiency-of-intermittent-hypoxia-intervention-in-primary-insomnia-100623289",false,"NCT07394699","Efficiency of Intermittent Hypoxia Intervention in Primary Insomnia","Inclusion Criteria:\n\n* Subjects are diagnosed with primary insomnia between 18 and 60 years old，gender is not limited.\n* Patients who are not taking sedative-hypnotic drugs or have stopped taking drugs for more than 2 weeks.\n* Residing in the plains all year round and not having been above 1500 meters above sea level in the past 30 days.\n* Quiet state SaO2 ≥ 90%, cerebral oxygen saturation 58-82%, heart rate 60-100 beats\u002Fmin, blood pressure 90-140\u002F60-90 mmHg, respiratory rate 16-20 times\u002Fmin.\n* No functional drinks, caffeine-containing beverages, or sleep-disturbing medications during the study period.\n\nExclusion Criteria:\n\n* Stroke onset in the past 3 months, other severe neurological diseases, such as epilepsy, intracranial infectious diseases or demyelination.\n* Uncontrolled hypertension (systolic blood pressure ≥200mmHg) with antihypertensive drugs before enrollment, other cardiovascular diseases.\n* History of pulmonary, hepatic, dermatologic, or hematologic diseases.\n* History of substance abuse.\n* Pregnancy, Severe sleep apnea and neurological disorders.","ALL","18 Years","60 Years",{"count":50,"type":51},30,"ESTIMATED","INTERVENTIONAL",[54],"NA","The purpose of this study was to understand the effectiveness of intermittent hypoxia in the treatment of primary insomnia.",[57],"Insomnia, Primary","NOT_YET_RECRUITING","2026-02-05",{"date":61,"type":62},"2026-02-06","ACTUAL",{"date":64,"type":51},"2026-04-01",{"date":66,"type":51},"2028-12-31",{"name":5,"class":6}]