[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100611685":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":34,"centralContacts":35,"locations":41,"responsibleParty":58,"collaborators":34,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":66,"eligibilityCriteria":67,"healthyVolunteers":62,"sex":68,"minAge":69,"maxAge":34,"enrollmentInfo":70,"targetDuration":34,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":79,"overallStatus":86,"whyStopped":34,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"National Taiwan University Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Recent Ejaculation Group","EXPERIMENTAL","Participants in this group will be instructed to have at least one ejaculation within 36 hours before surgery. Under anesthesia, they will undergo transrectal ultrasound (TRUS) to measure seminal vesicle volume prior to radical prostatectomy. Intraoperative dissection time, difficulty, and visual clarity will also be recorded.",[13],"Behavioral: Recent Ejaculation",{"label":15,"type":16,"description":17,"interventionNames":18},"Abstinence Group","ACTIVE_COMPARATOR","Participants in this group will be instructed to abstain from ejaculation for at least 72 hours before surgery. Under anesthesia, they will undergo transrectal ultrasound (TRUS) to measure seminal vesicle volume prior to radical prostatectomy. Intraoperative dissection time, difficulty, and visual clarity will also be recorded.",[19],"Behavioral: Preoperative Abstinence",[21,28],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Recent Ejaculation","Participants are instructed to ejaculate at least once within 36 hours prior to radical prostatectomy. This behavioral intervention is used to evaluate its effect on seminal vesicle volume and intraoperative dissection parameters.",[9],[27],"Ejaculation within 36 hours before surgery",{"type":22,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"Preoperative Abstinence","Participants are instructed to abstain from ejaculation for at least 72 hours prior to radical prostatectomy. This behavioral intervention is used to assess whether prolonged seminal vesicle filling affects intraoperative anatomy and dissection.",[15],[33],"Ejaculatory Abstinence ≥72 hours",null,[36],{"name":37,"role":38,"phone":39,"phoneExt":34,"email":40},"Yen Ho, M.D.","CONTACT","+886933092258","yenho.md@gmail.com",[42],{"facility":43,"status":34,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"National Taiwan University Cancer Center","Taipei","Outside U.S.\u002FCanada","106","Taiwan","TW",{"type":50,"coordinates":51},"Point",[52,53],121.52639,25.05306,{"lat":53,"lon":52},[56],{"name":37,"role":38,"phone":57,"phoneExt":34,"email":40},"886933092258",{"type":59,"investigatorFullName":34,"investigatorTitle":34,"investigatorAffiliation":34,"oldNameTitle":34,"oldOrganization":34},"SPONSOR","100611685","ejaculatory-behavior-and-seminal-vesicle-size-during-radical-prostatectomy-100611685",false,"NCT07243795","Ejaculatory Behavior and Seminal Vesicle Size During Radical Prostatectomy","Impact of Preoperative Ejaculation or Abstinence on Seminal Vesicle Size and Intraoperative Dissection Parameters During Radical Prostatectomy: A Randomized Controlled Trial","PreRP-EJAC","Inclusion Criteria:\n\n* Male patients aged 18 years or older\n* Histologically confirmed prostate cancer\n* Scheduled for radical prostatectomy\n* Able and willing to comply with assigned ejaculation or abstinence protocol\n* Willing to complete preoperative questionnaire\n* Willing to undergo transrectal ultrasound (TRUS) 12-14 hours before surgery\n* Able to understand and sign informed consent\n\nExclusion Criteria:\n\n* Prior bilateral seminal vesicle resection or congenital absence of seminal vesicles\n* Anatomical abnormalities preventing SV identification\n* Hormone therapy within 6 months before surgery\n* Inability to recall ejaculation history in the past 3 days\n* Inability to follow behavioral instructions or TRUS protocol\n* Severe anorectal disease or history of anorectal surgery preventing TRUS\n* Cognitive or psychiatric conditions impairing informed consent\n* Incomplete data or poor-quality imaging\n* Prior prostate cancer treatment\n* Belonging to a vulnerable population (e.g., minors, prisoners, pregnant individuals, cognitively impaired, etc.)","MALE","18 Years",{"count":71,"type":72},40,"ESTIMATED","INTERVENTIONAL",[75],"NA","The goal of this clinical trial is to learn if recent ejaculation or abstinence before surgery affects seminal vesicle size and dissection-related surgical factors in adult men with prostate cancer undergoing radical prostatectomy. The main questions it aims to answer are:\n\nDoes ejaculation within 36 hours before surgery reduce seminal vesicle size compared to abstinence of 72 hours or more?\n\nDoes seminal vesicle size affect the ease or difficulty of surgical dissection during radical prostatectomy?\n\nResearchers will compare an ejaculation group to an abstinence group to see if seminal vesicle volume and intraoperative surgical parameters differ between them.\n\nParticipants will:\n\nFollow specific instructions to either ejaculate or abstain before surgery\n\nUndergo a transrectal ultrasound (TRUS) to measure seminal vesicle size after anesthesia but before surgery\n\nHave their surgical dissection time and difficulty rated by the operating surgeon",[78],"Prostate Cancer Patients Undergoing Radical Prostatectomy",[80,81,82,83,84,85],"Prostate Cancer","Radical Prostatectomy","Seminal Vesicle","Ejaculation","Abstinence","Surgical Dissection","NOT_YET_RECRUITING","2025-11-25",{"date":89,"type":90},"2025-12-03","ACTUAL",{"date":92,"type":72},"2025-12-01",{"date":94,"type":72},"2026-10-09",{"name":5,"class":6},1]