[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100643481":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":28,"locations":34,"responsibleParty":50,"collaborators":12,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":12,"eligibilityCriteria":59,"healthyVolunteers":60,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":12,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":74,"overallStatus":36,"whyStopped":12,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Northwestern University","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Standard HoLEP","NO_INTERVENTION","HoLEP procedure performed using standard care technique.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"ES-HoLEP","ACTIVE_COMPARATOR","HoLEP procedure performed using ejaculatory-sparing HoLEP technique.",[18],"Other: Ejaculatory-sparing (ES-sparing) HoLEP",[20],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":12},"Ejaculatory-sparing (ES-sparing) HoLEP","The ejaculatory sparing technique involves sparing the distal apex of the prostate in particular the anterior portion of the prostate which will allow for coaptation necessary for antegrade ejaculation.",[14],[25],{"name":26,"affiliation":5,"role":27},"Amy E Krambeck, MD","PRINCIPAL_INVESTIGATOR",[29],{"name":30,"role":31,"phone":32,"phoneExt":12,"email":33},"Alyssa McDonald, MPH","CONTACT","312-695-8146","alyssa.mcdonald@northwestern.edu",[35],{"facility":5,"status":36,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"RECRUITING","Chicago","Illinois","60611","United States","US",{"type":43,"coordinates":44},"Point",[45,46],-87.65005,41.85003,{"lat":46,"lon":45},[49],{"name":26,"role":27,"phone":12,"phoneExt":12,"email":12},{"type":27,"investigatorFullName":51,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":12,"oldOrganization":12},"Amy Krambeck","Director of the Endourology\u002FStone Division","100643481","ejaculatory-sparing-holep-vs-standard-holep-100643481",false,"NCT07631286","Ejaculatory-Sparing HoLEP vs Standard HoLEP","Ejaculatory-sparing Holmium Laser Enucleation of the Prostate (HoLEP) vs Standard HoLEP: a Randomized Controlled Trial","Inclusion Criteria:\n\n\\- Patients who are sexually active with antegrade ejaculation who are undergoing HoLEP for the treatment of bothersome lower urinary tract symptoms.\n\nExclusion Criteria:\n\n* Patients with pre-existing retrograde ejaculation\n* Patients who are not sexually active\n* Patients with indwelling urinary catheter prior to surgery, neurological disease, or history of prior prostatic\u002Furethral surgery that may impact ejaculation\n* Patients who lack decisional capacity\n* Patients unable to read\u002Fspeak English",true,"MALE","18 Years","100 Years",{"count":65,"type":66},48,"ESTIMATED","INTERVENTIONAL",[69],"NA","The objective of this study is to compare a new surgical technique for HoLEP that will allow for sparing of ejaculation post-HoLEP.",[72,73],"Enlarged Prostate (BPH)","Enlarged Prostate With Lower Urinary Tract Symptoms",[75],"HoLEP","2026-06-05",{"date":78,"type":79},"2026-06-09","ACTUAL",{"date":81,"type":66},"2026-06",{"date":83,"type":66},"2028-05",{"name":5,"class":6},1]